Sampling procedures in estrogen receptor determinations.

Abstract:

:To determine the significance of proteolysis and delayed freezing of tumor samples on estrogen receptor levels, values from 19 of 31 biopsy specimens were compared with that in remaining tumor at the completion of mastectomy. There was a 15-100% decrease in receptor content. Time-decay studies on selected postmastectomy samples showed a further decrease in estrogen receptor content inversely proportional to the time it was exposed to room temperature. Factors that govern the valid measurement of receptor levels include tumor cell concentration, tumor necrosis, and time between devascularization of the specimen to freezing. A carefully procured histologically confirmed sample of fresh tumor is necessary for reliable estrogen receptor values.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Newsome JF,Avis FP,Hammond JE,Sherwood S

doi

10.1097/00000658-198105000-00003

subject

Has Abstract

pub_date

1981-05-01 00:00:00

pages

549-54

issue

5

eissn

0003-4932

issn

1528-1140

journal_volume

193

pub_type

杂志文章
  • Use of transcutaneous oxygen sensors to titrate PEEP.

    abstract::The relationship of transcutaneous oxygen tension (PtcO2) to arterial oxygen tension (PaO2), pulmonary shunt (Qsp/Qt), mixed venous oxygen tension (PVO2), and O2 delivery was determined in patients with respiratory failure in order to explore the possible usefulness of PtcO2 to titrate the level of positive end expira...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00014

    authors: Tremper KK,Waxman K,Shoemaker WC

    更新日期:1981-02-01 00:00:00

  • Elevated plasma transforming growth factor-beta 1 levels in breast cancer patients decrease after surgical removal of the tumor.

    abstract:OBJECTIVE:The authors determined whether untreated breast cancer patients have elevated plasma levels of transforming growth factor-beta 1 (TGF-beta 1). SUMMARY BACKGROUND DATA:Increased plasma TGF-beta 1 levels recently were found after chemotherapy in patients with advanced breast cancer. However, it currently is un...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199508000-00007

    authors: Kong FM,Anscher MS,Murase T,Abbott BD,Iglehart JD,Jirtle RL

    更新日期:1995-08-01 00:00:00

  • Low degree of formal education and musical experience predict degree of music-induced stress reduction in relatives and friends of patients: a single-center, randomized controlled trial.

    abstract:OBJECTIVE:To determine the factors that may predict music-induced relaxation in friends and family of patients in the emergency department. BACKGROUND:It remains unclear to date which demographic and experiential factors predict the effectiveness of music-induced relaxation. Furthermore, in-hospital stressors for frie...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e31828ee1da

    authors: Tilt AC,Werner PD,Brown DF,Alam HB,Warshaw AL,Parry BA,Jazbar B,Booker A,Stangenberg L,Fricchione GL,Benson H,Lillemoe KD,Conrad C

    更新日期:2013-05-01 00:00:00

  • Adrenergic control of adipocyte lipolysis in trauma and sepsis.

    abstract::Adipocyte lipolysis and its adrenergic control were studied in vitro from normal patients and those with trauma and sepsis. The adrenergic receptors were studied in terms of their responsiveness, a measure of the postreceptor mechanism, and their sensitivity, a measure of the receptor number or affinity. With early tr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198712000-00010

    authors: Forse RA,Leibel R,Askanazi J,Hirsch J,Kinney JM

    更新日期:1987-12-01 00:00:00

  • Improved surgical results for hilar cholangiocarcinoma with procedures including major hepatic resection.

    abstract:OBJECTIVE:To evaluate the long-term outcome of aggressive surgery incorporating hepatic resection and systematic nodal dissection for advanced carcinoma involving the hepatic hilus. SUMMARY BACKGROUND DATA:Few long-term results are available regarding radical surgery incorporating major hepatectomy and nodal dissectio...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000658-199911000-00008

    authors: Kosuge T,Yamamoto J,Shimada K,Yamasaki S,Makuuchi M

    更新日期:1999-11-01 00:00:00

  • Evaluation of splenic injury by computed tomography and its impact on treatment.

    abstract::We reviewed 37 consecutive, hemodynamically stable patients (16 adults, 21 children) who had splenic injuries diagnosed by computed tomography (CT) scan to compare the CT evaluation with operative assessment of injury and eventual treatment. Computed tomographic scans and operative findings were graded by a splenic in...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199005000-00009

    authors: Malangoni MA,Cué JI,Fallat ME,Willing SJ,Richardson JD

    更新日期:1990-05-01 00:00:00

  • Reperfusion inhibits elevated splanchnic prostanoid production after hemorrhagic shock.

    abstract::The effect of reperfusion following hemorrhagic shock on splanchnic prostanoid release was studied. Anesthetized male rats were bled to a mean arterial blood pressure of 30 mmHg for 30 minutes and either killed or treated with shed blood for 60 minutes and then killed. The superior mesenteric arterial bed was cannulat...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199012000-00006

    authors: Myers SI,Taylor BJ,Stanislawska M

    更新日期:1990-12-01 00:00:00

  • A systematic study of host defense processes in badly injured patients.

    abstract::A prospective study of factors predisposing to infection in badly injured patients has disclosed: the dominant roles of two specific parameters: monocyte antigen presenting capacity, and opsonic capacity of diluted serum; the potential value of further assessment of: the predictive value of plots of activated T-cells/...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:

    authors: Polk HC Jr,George CD,Wellhausen SR,Cost K,Davidson PR,Regan MP,Borzotta AP

    更新日期:1986-09-01 00:00:00

  • Lead poisoning from retained missiles. An experimental study.

    abstract::The problem of lead poisoning from bullets has been investigated by surgically implanting discs of lead, each enriched in a different natural isotope, into the tissue of two mongrel dogs and monitoring by mass spectrometry the release of the lead into each animal's blood over the course of 3 years. Lead placed in the ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198611000-00014

    authors: Manton WI,Thal ER

    更新日期:1986-11-01 00:00:00

  • Improving continuing medical education for surgical techniques: applying the lessons learned in the first decade of minimal access surgery.

    abstract:OBJECTIVE:To examine the first decade of experience with minimal access surgery, with particular attention to issues of training surgeons already in practice, and to provide a set of recommendations to improve technical training for surgeons in practice. SUMMARY BACKGROUND DATA:Concerns about the adequacy of training ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000658-200102000-00003

    authors: Rogers DA,Elstein AS,Bordage G

    更新日期:2001-02-01 00:00:00

  • Resting energy expenditure in controls and cancer patients with localized and diffuse disease.

    abstract::Resting energy expenditure (REE), nutritional parameters, and substrate levels were measured using a technique to minimize artifacts in 11 control patients, nine patients with localized, and four patients with diffuse neoplastic disease. Patients with diffuse disease had significantly increased percentage preillness w...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198403000-00008

    authors: Arbeit JM,Lees DE,Corsey R,Brennan MF

    更新日期:1984-03-01 00:00:00

  • Hospital length of stay after admission for traumatic injury in Canada: a multicenter cohort study.

    abstract:OBJECTIVE:To describe acute care length of stay (LOS) over all consecutive hospitalizations for the injury and according to level of care [intensive care unit (ICU), intermediate care, general ward], compare observed and expected LOS, and identify predictors of LOS. BACKGROUND:Prolonged LOS has important consequences ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000000624

    authors: Moore L,Stelfox HT,Turgeon AF,Nathens A,Bourgeois G,Lapointe J,Gagné M,Lavoie A

    更新日期:2014-07-01 00:00:00

  • Weekday of Esophageal Cancer Surgery and Its Relation to Prognosis.

    abstract:OBJECTIVE:To assess whether weekday of surgery influences long-term survival in esophageal cancer. BACKGROUND:Increased 30-day mortality rates have been reported in patients undergoing elective surgery later compared with earlier in the week. METHODS:This population-based cohort study included 98% of all esophageal c...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001324

    authors: Lagergren J,Mattsson F,Lagergren P

    更新日期:2016-06-01 00:00:00

  • Acute hand burns in children: management and long-term outcome based on a 10-year experience with 698 injured hands.

    abstract:OBJECTIVE:To document long-term results associated with an coordinated plan of care for acutely burned hands in children. SUMMARY AND BACKGROUND DATA:Optimal hand function is a crucial component of a high-quality survival after burn injury. This can be achieved only with a coordinated approach to the injuries. Long-te...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199904000-00016

    authors: Sheridan RL,Baryza MJ,Pessina MA,O'Neill KM,Cipullo HM,Donelan MB,Ryan CM,Schulz JT,Schnitzer JJ,Tompkins RG

    更新日期:1999-04-01 00:00:00

  • Caustic burns and carcinoma of the esophagus.

    abstract::A history of caustic injury was obtained in 12 of 846 patients with squamous cell carcinoma of the esophagus. The average age was 52.8 years; the interval from injury to development of carcinoma was 45.8 years. Nine of the 12 carcinomas were in the midthoracic segment. Resection was possible in nine patients, with two...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198108000-00005

    authors: Hopkins RA,Postlethwait RW

    更新日期:1981-08-01 00:00:00

  • Additional resection of an intraoperative margin-positive proximal bile duct improves survival in patients with hilar cholangiocarcinoma.

    abstract:OBJECTIVE:To assess the survival benefit of additional resection of an intraoperative positive proximal bile duct margin (BD(Marg)) in patients undergoing hepatectomy for hilar cholangiocarcinoma (HCCA). SUMMARY BACKGROUND DATA:Intraoperative evidence of invasive cancer at the proximal (BD(Marg)) is associated with a ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182368f85

    authors: Ribero D,Amisano M,Lo Tesoriere R,Rosso S,Ferrero A,Capussotti L

    更新日期:2011-11-01 00:00:00

  • Is childhood thyroid cancer a lethal disease?

    abstract::The clinical, pathological, surgical, postoperative findings and survivorship of 58 patients younger and 513 patients older than 21 years at the time of diagnosis with thyroid neoplasms are reported. The younger patients have a predominance of well differentiated carcinomas which are more likely to be follicular. The ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197505000-00018

    authors: Buckwalter JA,Thomas CG,Freeman JB

    更新日期:1975-05-01 00:00:00

  • Endovascular stent graft repair of abdominal and thoracic aortic aneurysms: a ten-year experience with 817 patients.

    abstract:OBJECTIVE:On November 23, 1992, the first endovascular stent graft (ESG) repair of an aortic aneurysm was performed in North America. Following the treatment of this patient, we have continued to evaluate ESG over the past 10 years in the treatment of 817 patients. SUMMARY AND BACKGROUND DATA:Abdominal (AAA) or thorac...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.sla.0000090473.63393.e9

    authors: Marin ML,Hollier LH,Ellozy SH,Spielvogel D,Mitty H,Griepp R,Lookstein RA,Carroccio A,Morrissey NJ,Teodorescu VJ,Jacobs TS,Minor ME,Sheahan CM,Chae K,Oak J,Cha A

    更新日期:2003-10-01 00:00:00

  • A manometric study of anal fissure treated by subcutaneous lateral internal sphincterotomy.

    abstract::A prospective, manometric trial of anal fissure treated by subcutaneous lateral internal sphincterotomy (SLIS) was designed to elucidate the pathophysiology of this condition. Anorectal manometry with a closed, precalibrated, water-filled microballoon using the station pull-through technique was performed on 13 patien...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199002000-00017

    authors: McNamara MJ,Percy JP,Fielding IR

    更新日期:1990-02-01 00:00:00

  • Career decisions and the structure of training: an American Board Of Colon and Rectal Surgery survey of colorectal residents.

    abstract:OBJECTIVE:To investigate potential impacts of restructuring general surgery training on colorectal (CR) surgery recruitment and expertise. SUMMARY BACKGROUND DATA:In response to the American Surgical Association Blue Ribbon Committee report on surgical education (2004), the American Board of Colon and Rectal Surgery, ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181ad64f1

    authors: Schmitz CC,Rothenberger DA,Trudel JL,Wolff BG

    更新日期:2009-07-01 00:00:00

  • Use of Prophylactic Mesh When Creating a Colostomy Does Not Prevent Parastomal Hernia: A Randomized Controlled Trial-STOMAMESH.

    abstract:OBJECTIVE:The aim of this study was to determine whether parastomal hernia (PSH) rate can be reduced by using synthetic mesh in the sublay position when constructing permanent end colostomy. The secondary aim was to investigate possible side-effects of the mesh. BACKGROUND:Prevention of PSH is important as it often ca...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/SLA.0000000000002542

    authors: Odensten C,Strigård K,Rutegård J,Dahlberg M,Ståhle U,Gunnarsson U,Näsvall P

    更新日期:2019-03-01 00:00:00

  • New technique for liver resection using heat coagulative necrosis.

    abstract:OBJECTIVE:To assess a new bloodless technique using radiofrequency energy for segmental liver resection of hepatic tumors. SUMMARY BACKGROUND DATA:Liver resection remains a formidable surgical procedure; safe performance requires a high level of training and skill. Intraoperative blood loss during liver resection rema...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200211000-00004

    authors: Weber JC,Navarra G,Jiao LR,Nicholls JP,Jensen SL,Habib NA

    更新日期:2002-11-01 00:00:00

  • Recurrent carotid stenosis. A five-year series of 65 reoperations.

    abstract::From 1979 to 1983, 1726 carotid endarterectomies were performed at the Cleveland Clinic. During this period, 39 men (mean age, 60 years) and 22 women (mean age, 63 years) required 65 reoperations (3.8%) for correction of recurrent carotid stenosis occurring 3 to 194 months (mean, 42 months) after previous endarterecto...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198507000-00004

    authors: Das MB,Hertzer NR,Ratliff NB,O'Hara PJ,Beven EG

    更新日期:1985-07-01 00:00:00

  • Very long-term objective evaluation of heller myotomy plus posterior partial fundoplication in patients with achalasia of the cardia.

    abstract:OBJECTIVE:To present the objectively assessed very long-term results of a prospective study of 149 patients with achalasia of the cardia who underwent Heller myotomy and posterior partial fundoplication. SUMMARY BACKGROUND DATA:Very few studies evaluate objectively the very long-term results to analyze whether the eff...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318159d7dd

    authors: Ortiz A,de Haro LF,Parrilla P,Lage A,Perez D,Munitiz V,Ruiz D,Molina J

    更新日期:2008-02-01 00:00:00

  • Mucosal damage in the esophageal remnant after esophagectomy and gastric transposition.

    abstract:OBJECTIVE:To assess development of mucosal damage in the esophageal remnant in regard to the level of the esophagogastrostomy reconstruction either in a right chest or in a left neck position. SUMMARY BACKGROUND DATA:Esophagectomy with gastric interposition creates an in vivo human model of pathologic esophageal reflu...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31818eec06

    authors: D'Journo XB,Martin J,Rakovich G,Brigand C,Gaboury L,Ferraro P,Duranceau A

    更新日期:2009-02-01 00:00:00

  • Challenges and Opportunities for the Academic Mission Within Expanding Health Systems: A Qualitative Study.

    abstract:OBJECTIVE:To explore challenges and opportunities for surgery departments' academic missions as they become increasingly affiliated with expanding health systems. SUMMARY BACKGROUND DATA:Academic medicine is in the midst of unprecedented change. In addition to facing intense competition, narrower margins, and decrease...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004462

    authors: Chhabra KR,Diaz A,Byrnes MA,Rajkumar A,Yang P,Dimick JB,Nathan H

    更新日期:2020-11-12 00:00:00

  • The relationship between extent of thyroid cancer surgery and use of radioactive iodine.

    abstract:UNLABELLED:By linking surgeon surveys to the National Cancer Database, we found that surgeons' tendency to perform more extensive thyroid resection is associated with greater use of radioactive iodine for stage I thyroid cancer. OBJECTIVE:To determine the relationships between surgeon recommendations for extent of res...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31826c8915

    authors: Haymart MR,Banerjee M,Yang D,Stewart AK,Doherty GM,Koenig RJ,Griggs JJ

    更新日期:2013-08-01 00:00:00

  • Hospital Volume of Antireflux Surgery in Relation to Endoscopic and Surgical Re-interventions.

    abstract:OBJECTIVE:To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. BACKGROUND:Antireflux surgery for gastro-esophageal reflux disease is followed by varying rates of re-interventions. Whether hospital volume influences re-intervention rates is...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003776

    authors: Markar S,Santoni G,Maret-Ouda J,Artama M,Färkkilä M,Lynge E,Pukkala E,Ness-Jensen E,von Euler-Chelpin M,Lagergren J

    更新日期:2020-01-06 00:00:00

  • Comparison of randomized controlled trial registry entries and content of reports in surgery journals.

    abstract:OBJECTIVE:To evaluate discrepancies between trial registry entries and final reports of randomized controlled trials (RCTs) published in major general surgical journals. BACKGROUND:Health care decisions are based on published results in peer-reviewed journals. Mandatory trial registration was introduced to increase tr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318283cf7f

    authors: Rosenthal R,Dwan K

    更新日期:2013-06-01 00:00:00

  • Pancreatic reg gene expression is inhibited during cellular differentiation.

    abstract:BACKGROUND AND OBJECTIVE:Factors that control pancreatic regenerating (reg I) gene expression are unknown, but it is believed that its expression may correspond with cellular differentiation. The authors recently demonstrated that reg I is expressed in AR42J, a rat acinar cell line whose state of differentiation can be...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199703000-00013

    authors: Zenilman ME,Magnuson TH,Perfetti R,Chen J,Shuldiner AR

    更新日期:1997-03-01 00:00:00