Resting energy expenditure in controls and cancer patients with localized and diffuse disease.

Abstract:

:Resting energy expenditure (REE), nutritional parameters, and substrate levels were measured using a technique to minimize artifacts in 11 control patients, nine patients with localized, and four patients with diffuse neoplastic disease. Patients with diffuse disease had significantly increased percentage preillness weight loss (15.4 +/- 7.0%), decreased arm muscle circumference (21.9 +/- 2.1 vs. 26.2 +/- 3.5 cm), serum albumin (3.6 +/- 0.6 vs. 4.4 +/- 0.2 g/dl), total lymphocyte count (1024 +/- 613 vs. 1796 +/- 495 cells/mm3), and creatinine-height index (0.68 +/- 0.16 vs. 1.18 +/- 0.37) compared to controls. Both groups of cancer patients had significantly increased REE compared to controls: 25.6 +/- 3.7 (diffuse), 21.4 +/- 3.7 (localized), vs. 18.1 +/- 2.9 kcal/kg/d (controls). However, when REE was expressed as a function of metabolic body size, the significant difference persisted only in the patients with diffuse disease compared to controls: 71.8 +/- 16.4 vs. 53.9 +/- 8.1 kcal/kg3/4/d. Patients studied pre- and posttumor resection all had a postoperative drop in their REE, which was significantly correlated with the measured tumor volume. In this homogeneous, select group of patients, the tumor-bearing state exerts a moderate impact on nutritional and metabolic parameters, which are probably related to the extent of disease.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Arbeit JM,Lees DE,Corsey R,Brennan MF

doi

10.1097/00000658-198403000-00008

subject

Has Abstract

pub_date

1984-03-01 00:00:00

pages

292-8

issue

3

eissn

0003-4932

issn

1528-1140

journal_volume

199

pub_type

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    authors: Mearadji A,Breeman W,Hofland L,van Koetsveld P,Marquet R,Jeekel J,Krenning E,van Eijck C

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    authors: Tsang WW,Chung CC,Kwok SY,Li MK

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    journal_title:Annals of surgery

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    pub_type: 杂志文章,实务指引

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    authors: Stain SC,Guthrie CR,Yellin AE,Donovan AJ

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    pub_type: 杂志文章

    doi:10.1097/00000658-199401000-00012

    authors: Pereira JA,Torregrosa MA,Martínez-Ródenas F,Clària J,Pallarés L,Gubern JM,Ruano-Gil D,Sitges-Serra A

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  • Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial.

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    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/SLA.0000000000001487

    authors: Ziegler TR,May AK,Hebbar G,Easley KA,Griffith DP,Dave N,Collier BR,Cotsonis GA,Hao L,Leong T,Manatunga AK,Rosenberg ES,Jones DP,Martin GS,Jensen GL,Sax HC,Kudsk KA,Galloway JR,Blumberg HM,Evans ME,Wischmeyer PE

    更新日期:2016-04-01 00:00:00