Patterns of failure in patients with resected stage I and II non-small-cell carcinoma of the lung. The Ludwig Lung Cancer Study Group.

Abstract:

:The pattern of failure was studied in 1012 patients with resected Stage I or II non-small-cell carcinoma of the lung. Initial intrathoracic failure (41%) was more common than initial extrathoracic failure (34%) even though a complete resection was the intent in all patients. The most frequent sites of initial failure were the bronchial resection line (16%) and the central nervous system (CNS) (15%). The site distribution of initial failure does not appear to depend on TNM stage or pattern of nodal involvement. Patients with poorly differentiated disease had a greater rate of initial extrathoracic failure (p less than 0.01), predominantly bone or CNS. Implications for therapy and future research are discussed.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

doi

10.1097/00000658-198701000-00012

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

67-71

issue

1

eissn

0003-4932

issn

1528-1140

journal_volume

205

pub_type

杂志文章
  • Parietal cell vagotomy as an emergency procedure for bleeding peptic ulcer.

    abstract::Twenty-three selected patients presenting with massive bleeding from peptic ulcers underwent emergency parietal cell vagotomy (PCV). Nineteen patients had a duodenal ulcer, two a prepyloric ulcer, and one a gastric ulcer. The patients were studied retrospectively with regard to postoperative mortality and morbidity, e...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198711000-00005

    authors: Hoffmann J,Devantier A,Koelle T,Jensen HE

    更新日期:1987-11-01 00:00:00

  • The influence of mechanical bowel preparation in elective lower colorectal surgery.

    abstract:OBJECTIVE:This study evaluates the effects of mechanical bowel preparation (MBP) on anastomosis below the peritoneal verge and questions the influence of MBP on anastomotic leakage in combination with a diverting ileostomy in lower colorectal surgery. SUMMARY BACKGROUND DATA:In a previous large multicenter randomized ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181c0e75c

    authors: Van't Sant HP,Weidema WF,Hop WC,Oostvogel HJ,Contant CM

    更新日期:2010-01-01 00:00:00

  • Metabolic changes in patients severely affected by tetanus.

    abstract::Metabolic changes in six severely affected tetanus patients suffering from characteristic labile hypertension (maximum systolic blood pressure greater than 200 mmHG, maximum diurnal change in systolic pressure greater than 100 mmHg) were investigated. Daily urinary excretion of urea nitrogen increased gradually from t...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199101000-00011

    authors: Hiraide A,Katayama M,Sugimoto H,Yoshioka T,Sugimoto T

    更新日期:1991-01-01 00:00:00

  • Long-term follow-up of a randomized trial comparing the beger and frey procedures for patients suffering from chronic pancreatitis.

    abstract:OBJECTIVE:To report on the long-term follow-up of a randomized clinical trial comparing pancreatic head resection according to Beger and limited pancreatic head excision combined with longitudinal pancreatico-jejunostomy according to Frey for surgical treatment of chronic pancreatitis. SUMMARY BACKGROUND DATA:Resectio...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.sla.0000157268.78543.03

    authors: Strate T,Taherpour Z,Bloechle C,Mann O,Bruhn JP,Schneider C,Kuechler T,Yekebas E,Izbicki JR

    更新日期:2005-04-01 00:00:00

  • Sentinel node skills verification and surgeon performance: data from a multicenter clinical trial for early-stage breast cancer.

    abstract:OBJECTIVE:Marked variations in sentinel lymph node dissection (SLND) technique have been identified, and definitive qualifications for SLND performance remain controversial. Based on previous reports and expert opinion, we predicted that 20 to 30 cases of SLND with axillary lymph node dissection (ALND) would enable sur...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/01.sla.0000184210.68646.77

    authors: Posther KE,McCall LM,Blumencranz PW,Burak WE Jr,Beitsch PD,Hansen NM,Morrow M,Wilke LG,Herndon JE 2nd,Hunt KK,Giuliano AE

    更新日期:2005-10-01 00:00:00

  • Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients.

    abstract:OBJECTIVES:Recent data from Iraq supporting early aggressive use of fresh frozen plasma (FFP) in a 1:1 ratio to packed red blood cells (PRBCs) has led many civilian trauma centers to adopt this resource intensive strategy. METHODS:Prospective data were collected on 806 consecutive trauma patients admitted to the inten...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31818990ed

    authors: Scalea TM,Bochicchio KM,Lumpkins K,Hess JR,Dutton R,Pyle A,Bochicchio GV

    更新日期:2008-10-01 00:00:00

  • Multicenter Canadian study of prehospital trauma care.

    abstract:OBJECTIVE:To evaluate whether the type of on-site care a trauma patient receives affects outcome. SUMMARY BACKGROUND DATA:The controversy regarding the prehospital care of trauma patients between Advanced Life Support (ALS) and Basic Life Support (BLS) is ongoing. Due to this unresolved controversy, as well as histori...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.SLA.0000048374.46952.10

    authors: Liberman M,Mulder D,Lavoie A,Denis R,Sampalis JS

    更新日期:2003-02-01 00:00:00

  • Surgical approach to bismuth Type I and II hilar cholangiocarcinomas: audit of 54 consecutive cases.

    abstract:OBJECTIVE:To clarify the optimal surgical strategy for Bismuth type I and II hilar cholangiocarcinomas. SUMMARY BACKGROUND DATA:Local or hilar resections is often performed for Bismuth type I and II tumors; however, reported outcomes have been unsatisfactory with a high recurrence and low survival rate. To improve sur...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318142d97e

    authors: Ikeyama T,Nagino M,Oda K,Ebata T,Nishio H,Nimura Y

    更新日期:2007-12-01 00:00:00

  • Primary Open Versus Closed Implantation Strategy for Totally Implantable Venous Access Ports: The Multicentre Randomized Controlled PORTAS-3 Trial (DRKS 00004900).

    abstract:OBJECTIVES:PORTAS-3 was designed to compare the frequency of pneumothorax or haemothorax in a primary open versus closed strategy for port implantation. BACKGROUND DATA:The implantation strategy for totally implantable venous access ports with the optimal benefit/risk ratio remains unclear. METHODS:PORTAS-3 was a mul...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003705

    authors: Hüttner FJ,Bruckner T,Hackbusch M,Weitz J,Bork U,Kotschenreuther P,Heupel O,Kümmel S,Schlitt HJ,Mattulat M,Pintér L,Seiler CM,Gutt CN,Nottberg HS,Pohl A,Ghanem F,Meyer T,Imdahl A,Neudecker J,Müller VA,Gehrig T,R

    更新日期:2020-12-01 00:00:00

  • Management of external gastrointestinal fistulas.

    abstract::We analyzed the course of 186 patients with external gastrointestinal fistulas treated at the University of California Medical Center, San Francisco from 1968 to 1977. There were 82 patients in the earlier group (1968-1971) and 104 patients in the later group (1972-1977). The groups differed in that 35% of patients in...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197810000-00003

    authors: Reber HA,Roberts C,Way LW,Dunphy JE

    更新日期:1978-10-01 00:00:00

  • Duodenum-preserving resection of the head of the pancreas in chronic pancreatitis. A prospective, randomized trial.

    abstract:OBJECTIVE:Two techniques of duodenum-preserving resection of the head of the pancreas were compared in a prospective, randomized trial. The technical feasibility and effects on quality of life were assessed. SUMMARY BACKGROUND DATA:Drainage and resection are the principles of surgery in chronic pancreatitis. The techn...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-199504000-00004

    authors: Izbicki JR,Bloechle C,Knoefel WT,Kuechler T,Binmoeller KF,Broelsch CE

    更新日期:1995-04-01 00:00:00

  • National Trends in Readmission Following Inpatient Surgery in the Hospital Readmissions Reduction Program Era.

    abstract:OBJECTIVE:The aim of this study was to investigate whether the Hospital Readmissions Reduction Program, a national program that introduced financial penalties for high readmission rates for certain medical conditions, had a "spillover" effect on surgical conditions. SUMMARY BACKGROUND DATA:During the past decade, ther...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002350

    authors: Mehtsun WT,Papanicolas I,Zheng J,Orav EJ,Lillemoe KD,Jha AK

    更新日期:2018-04-01 00:00:00

  • Failure-to-pursue rescue: explaining excess mortality in elderly emergency general surgical patients with preexisting "do-not-resuscitate" orders.

    abstract:OBJECTIVE:To describe the outcomes of elderly patients with do-not-resuscitate (DNR) status who undergo emergency general surgery and to improve understanding of the relationship between preoperative DNR status and postoperative mortality. BACKGROUND:Preoperative DNR status has previously been shown to predict increas...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31826578fb

    authors: Scarborough JE,Pappas TN,Bennett KM,Lagoo-Deenadayalan S

    更新日期:2012-09-01 00:00:00

  • Innovation in surgery: a historical perspective.

    abstract:OBJECTIVE:To describe the field of surgical innovation from a historical perspective, applying new findings from research in technology innovation. BACKGROUND:While surgical innovation has a rich tradition, as a field of study it is embryonic. Only a handful of academic centers of surgical innovation exist, all of whi...

    journal_title:Annals of surgery

    pub_type: 历史文章,杂志文章,评审

    doi:10.1097/01.sla.0000242706.91771.ce

    authors: Riskin DJ,Longaker MT,Gertner M,Krummel TM

    更新日期:2006-11-01 00:00:00

  • Brush border transport of glutamine and other substrates during sepsis and endotoxemia.

    abstract::The effects of severe infection on luminal transport of amino acids and glucose by the small intestine were investigated. Studies were done in endotoxin-treated rats and in septic patients who underwent resection of otherwise normal small bowel. In rats the kinetics of the brush border glutamine transporter and the gl...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199105000-00004

    authors: Salloum RM,Copeland EM,Souba WW

    更新日期:1991-05-01 00:00:00

  • Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer.

    abstract:OBJECTIVE:This study aimed at: (1) documenting the evolution of surgical results of esophagectomy in a high-volume center, (2) identifying predictive factors of pulmonary complications and mortality, and (3) examining whether preoperative chemoradiation therapy would complicate postoperative recovery. SUMMARY BACKGROU...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000143123.24556.1c

    authors: Law S,Wong KH,Kwok KF,Chu KM,Wong J

    更新日期:2004-11-01 00:00:00

  • Donating a Kidney to a Stranger: A Review of the Benefits and Controversies of Unspecified Kidney Donation.

    abstract:OF BACKGROUND DATA:Unspecified kidney donation (UKD) describes living donation of a kidney to a stranger. The practice is playing an increasingly important role within the transplant programme in the United Kingdom, where these donors are commonly used to trigger a chain of transplants; thereby amplifying the benefit d...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SLA.0000000000003855

    authors: Maple H,Draper H,Gogalniceanu P,Burnapp L,Chilcot J,Mamode N

    更新日期:2020-07-01 00:00:00

  • Minimally invasive cardiac valve surgery improves patient satisfaction while reducing costs of cardiac valve replacement and repair.

    abstract:OBJECTIVE:This study compares the quality of valve replacement and repair performed through minimally invasive incisions as compared to the standard operation for aortic and mitral valve replacement. SUMMARY BACKGROUND DATA:With the advent of minimally invasive laparoscopic approaches to orthopedic surgery, urology, g...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199710000-00003

    authors: Cohn LH,Adams DH,Couper GS,Bichell DP,Rosborough DM,Sears SP,Aranki SF

    更新日期:1997-10-01 00:00:00

  • Timing But Not Patterns of Recurrence Is Different Between Node-negative and Node-positive Resected Pancreatic Cancer.

    abstract:OBJECTIVE:Our aim was to evaluate recurrence patterns of surgically resected PDAC patients with negative (pN0) or positive (pN1) lymph nodes. SUMMARY BACKGROUND DATA:Pancreatic ductal adenocarcinoma (PDAC) is predicted to become the second leading cause of cancer death by 2030. This is mostly due to early local and di...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000003123

    authors: Honselmann KC,Pergolini I,Castillo CF,Deshpande V,Ting D,Taylor MS,Bolm L,Qadan M,Wellner U,Sandini M,Bausch D,Warshaw AL,Lillemoe KD,Keck T,Ferrone CR

    更新日期:2020-08-01 00:00:00

  • Intragastric microbial colonization in common disease states of the stomach and duodenum.

    abstract::Forty-nine patients undergoing elective or emergent gastric surgery have been included in this study. Gastric needle aspiration was performed at the time of surgery in each case, followed by qualitative aerobic and anaerobic bacteriologic analysis. In 18 patients undergoing elective operation for chronic nonobstructin...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197511000-00004

    authors: Nichols RL,Smith JW

    更新日期:1975-11-01 00:00:00

  • Abdominal aortic aneurysm in high-risk patients. Outcome of selective management based on size and expansion rate.

    abstract::Low mortality rates for elective surgical treatment of abdominal aortic aneurysms justify an aggressive approach in most patients. However, in high-risk patients with small aneurysms and no symptoms, the decision to operate remains a delicate balance of risk and benefit. Our observations include 99 high-risk patients ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198409000-00003

    authors: Bernstein EF,Chan EL

    更新日期:1984-09-01 00:00:00

  • The role of tumor necrosis factor and nitric oxide in the acute cardiovascular response to endotoxin.

    abstract:OBJECTIVE:This study was designed to examine the differential effects of tumor necrosis factor (TNF) and nitric oxide on the acute cardiovascular changes that occur in response to endotoxemia. SUMMARY BACKGROUND DATA:Recent studies have suggested that some, if not all, of the cardiovascular effects of TNF are mediated...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199601000-00009

    authors: Fahey TJ 3rd,Yoshioka T,Shires GT,Fantini GA

    更新日期:1996-01-01 00:00:00

  • Use of transcutaneous oxygen sensors to titrate PEEP.

    abstract::The relationship of transcutaneous oxygen tension (PtcO2) to arterial oxygen tension (PaO2), pulmonary shunt (Qsp/Qt), mixed venous oxygen tension (PVO2), and O2 delivery was determined in patients with respiratory failure in order to explore the possible usefulness of PtcO2 to titrate the level of positive end expira...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00014

    authors: Tremper KK,Waxman K,Shoemaker WC

    更新日期:1981-02-01 00:00:00

  • Distal splenorenal shunt (DSS) in children: analysis of the first 21 consecutive cases.

    abstract::Twenty-one children from the ages of 4 to 12 years old were treated for esophageal hemorrhage by distal splenorenal shunt (DSS). In four patients, thrombosis of the shunt occurred within the first 24 hours after operation. In the other 17 children, long-term shunt patency was verified. Only one thrombosis has occurred...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198204000-00004

    authors: Maksoud JG,Mies S

    更新日期:1982-04-01 00:00:00

  • Outcome following surgical management of corrosive strictures of the esophagus.

    abstract:OBJECTIVE:To analyze the short- and long-term outcomes following surgical treatment for corrosive stricture of the esophagus. BACKGROUND:Surgery is a well-established treatment for corrosive strictures of the esophagus and involves either resection or bypass of the damaged esophagus and replacement by a conduit. The n...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182125ce7

    authors: Javed A,Pal S,Dash NR,Sahni P,Chattopadhyay TK

    更新日期:2011-07-01 00:00:00

  • Prolonged continuous or intermittent vascular inflow occlusion during hemihepatectomy in pigs.

    abstract:OBJECTIVE:To assess ischemia and reperfusion (I/R) injury in a hemihepatectomy model in pigs after prolonged continuous or intermittent vascular inflow occlusion in the liver. SUMMARY BACKGROUND DATA:Massive intraoperative blood loss during liver resections can be prevented by temporary vascular inflow occlusion, cons...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199903000-00011

    authors: van Wagensveld BA,van Gulik TM,Gelderblom HC,Scheepers JJ,Bosma A,Endert E,Gouma DJ

    更新日期:1999-03-01 00:00:00

  • Sciatic and Femoral Nerve Resection During Extended Radical Surgery for Advanced Pelvic Tumours: Long-term Survival, Functional, and Quality-of-life Outcomes.

    abstract:OBJECTIVE:To report survival, functional, and quality-of-life (QoL) outcomes after extended radical resection for advanced pelvic tumors with en bloc sciatic or femoral nerve resection. BACKGROUND:Advanced pelvic tumors involving the sciatic or femoral nerve have traditionally been considered inoperable. Small studies...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003390

    authors: Brown KGM,Solomon MJ,Lau YC,Steffens D,Austin KKS,Lee PJ

    更新日期:2019-06-07 00:00:00

  • Restoration of normal distensive characteristics of the esophagogastric junction after fundoplication.

    abstract:OBJECTIVE:To study the mechanical characteristics of the esophagogastric junction (EGJ) of postfundoplication patients and compare them with previously reported data on normal subjects and GERD patients. METHODS:Eight normal subjects, 9 GERD patients, and 8 fundoplication patients were studied with concurrent manometr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000167868.44211.f0

    authors: Pandolfino JE,Curry J,Shi G,Joehl RJ,Brasseur JG,Kahrilas PJ

    更新日期:2005-07-01 00:00:00

  • Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma.

    abstract:OBJECTIVE:To evaluate the current knowledge on the risk factors for recurrence, efficacy of adjuvant therapy in preventing recurrence, and the optimal management of recurrence after resection of hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA:The long-term prognosis after resection of HCC remains unsatisfactor...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000658-200007000-00003

    authors: Tung-Ping Poon R,Fan ST,Wong J

    更新日期:2000-07-01 00:00:00

  • General surgical complications can be predicted after cardiopulmonary bypass.

    abstract:OBJECTIVE:The authors review the general surgical complications of cardiopulmonary bypass, including newer procedures such as heart and lung transplantation, to identify patients at higher risk. SUMMARY BACKGROUND DATA:Although rare, the general surgical complications of cardiopulmonary bypass are associated with high...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199505000-00006

    authors: Spotnitz WD,Sanders RP,Hanks JB,Nolan SP,Tribble CG,Bergin JD,Zacour RK,Abbott RD,Kron IL

    更新日期:1995-05-01 00:00:00