A systematic study of host defense processes in badly injured patients.

Abstract:

:A prospective study of factors predisposing to infection in badly injured patients has disclosed: the dominant roles of two specific parameters: monocyte antigen presenting capacity, and opsonic capacity of diluted serum; the potential value of further assessment of: the predictive value of plots of activated T-cells/total T-cells versus monocyte antigen presenting capacity, the apparent protective effect of the ability to sharply increase specific IgM in response to infection, and the apparent protective effect of cytomegalovirus (CMV) infection in the first 28 days after injury against major bacterial infection; the lack of value of analysis of other T- and B-cell subsets in such patients; and the need to clarify CMV and transfusion status with respect to interpretation of such data. The specific role of variable transfusion and of specific serum immunoglobulins will require further and more discriminating study.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Polk HC Jr,George CD,Wellhausen SR,Cost K,Davidson PR,Regan MP,Borzotta AP

subject

Has Abstract

pub_date

1986-09-01 00:00:00

pages

282-99

issue

3

eissn

0003-4932

issn

1528-1140

journal_volume

204

pub_type

杂志文章
  • Do differences in hospital and surgeon quality explain racial disparities in lower-extremity vascular amputations?

    abstract:OBJECTIVE:To understand whether racial disparities in surgery for lower-extremity arterial disease are minimized by high-quality providers, or instead, differential treatment of otherwise similar patients pervades all settings. SUMMARY BACKGROUND DATA:Black patients are substantially more likely than whites to undergo...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181b41d53

    authors: Regenbogen SE,Gawande AA,Lipsitz SR,Greenberg CC,Jha AK

    更新日期:2009-09-01 00:00:00

  • Interferon regulatory factor expression in human breast cancer.

    abstract:OBJECTIVE:To investigate the expression of interferon regulatory factors 1 and 2 (IRF-1 and IRF-2) in human breast cancer. SUMMARY BACKGROUND DATA:Interferon regulatory factors 1 and 2 are transcription factors in the interferon gamma signal transduction pathway. IRF-1 acts as the effector arm of the interferon gamma ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200105000-00005

    authors: Doherty GM,Boucher L,Sorenson K,Lowney J

    更新日期:2001-05-01 00:00:00

  • Controlled clinical trial of selective decontamination for the treatment of severe acute pancreatitis.

    abstract:OBJECTIVE:A randomized, controlled, multicenter trial was undertaken in 102 patients with objective evidence of severe acute pancreatitis to evaluate whether selective decontamination reduces mortality. SUMMARY BACKGROUND DATA:Secondary pancreatic infection is the major cause of death in patients with acute necrotizin...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00000658-199507000-00010

    authors: Luiten EJ,Hop WC,Lange JF,Bruining HA

    更新日期:1995-07-01 00:00:00

  • Human umbilical veins and autogenous veins as canine arterial bypass grafts.

    abstract::Glutaraldehyde treated human umbilical veins (Dardik Biograft) were used to bypass short segments of the femoral artery in 15 dogs and were compared to autogenous jugular veins placed in the contralateral femoral artery of each animal. All 15 autogenous jugular veins remained patent for the four month period of observ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197808000-00005

    authors: Oblath RW,Buckley FO Jr,Donnelly WA,Green RM,Deweese JA

    更新日期:1978-08-01 00:00:00

  • A prospective, randomized, controlled trial of preoperative transarterial chemoembolization for resectable large hepatocellular carcinoma.

    abstract:OBJECTIVE:To evaluate the effect of preoperative transarterial chemoembolization (TACE) for resectable large hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA:Resection of HCC is potentially curative, but local recurrence is very common. There is currently no effective neoadjuvant or adjuvant therapy. METHODS:F...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e3181961c16

    authors: Zhou WP,Lai EC,Li AJ,Fu SY,Zhou JP,Pan ZY,Lau WY,Wu MC

    更新日期:2009-02-01 00:00:00

  • Arginine transport in human liver. Characterization and effects of nitric oxide synthase inhibitors.

    abstract:OBJECTIVE:Arginine transport was characterized and studied in human liver. SUMMARY BACKGROUND DATA:Plasma arginine uptake may regulate hepatocyte intracellular availability and the subsequent biosynthesis of nitric oxide (NO), but little is known about arginine transport across the human hepatocyte plasma membrane. M...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199309000-00014

    authors: Inoue Y,Bode BP,Beck DJ,Li AP,Bland KI,Souba WW

    更新日期:1993-09-01 00:00:00

  • Effect of proximal gastric vagotomy on feeding stimulated Heidenhain pouch acid secretion and gastrin release.

    abstract::Truncal vagotomy (TV) is known to increase the feeding stimulated acid output of Heidenhain pouches. A series of experiments were performed in dogs to see if proximal gastric vagotomy (PGV) also had this effect. Dogs were prepared with gastric fistulas (GF) and Heidenhain pouches (HP). Gastric function testing include...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197811000-00011

    authors: Harmon JW,Trout HH 3rd

    更新日期:1978-11-01 00:00:00

  • Prophylactic Mesh Placement During Formation of an End-colostomy Reduces the Rate of Parastomal Hernia: Short-term Results of the Dutch PREVENT-trial.

    abstract:OBJECTIVE:The aim of this study was to investigate the incidence of parastomal hernias (PSHs) after end-colostomy formation using a polypropylene mesh in a randomized controlled trial versus conventional colostomy formation. BACKGROUND:A PSH is the most frequent complication after stoma formation. Symptoms may range f...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000001903

    authors: Brandsma HT,Hansson BM,Aufenacker TJ,van Geldere D,Lammeren FM,Mahabier C,Makai P,Steenvoorde P,de Vries Reilingh TS,Wiezer MJ,de Wilt JH,Bleichrodt RP,Rosman C,Dutch Prevent Study group.

    更新日期:2017-04-01 00:00:00

  • Brochial stump closure techniques following pneumonectomy: A serial comparative study.

    abstract::Three methods of closing bronchial stumps were evaluated in 90 dogs undergoing left pneumonectomy:interrupted 3-0 silk sutures, interrupted 3-0 nylon sutures, and stapling with an automatic device. The dogs were sacrificed at 24 hours, 3, 5, 7, 10, and 14 days after pneumonectomy. Brochial stump leakage pressures and ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197608000-00012

    authors: Scott RN,Faraci RP,Hough A,Chretien PB

    更新日期:1976-08-01 00:00:00

  • Minimally invasive esophagectomy: outcomes in 222 patients.

    abstract:OBJECTIVE:To assess our outcomes after minimally invasive esophagectomy (MIE). SUMMARY BACKGROUND DATA:Esophagectomy has traditionally been performed by open methods. Results from most series include mortality rates in excess of 5% and hospital stays frequently greater than 10 days. MIE has the potential to improve th...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000089858.40725.68

    authors: Luketich JD,Alvelo-Rivera M,Buenaventura PO,Christie NA,McCaughan JS,Litle VR,Schauer PR,Close JM,Fernando HC

    更新日期:2003-10-01 00:00:00

  • A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation.

    abstract:PURPOSE:Surgical resection provides the only possibility of cure for pancreas cancer. A standard adjuvant approach has not been established. We tested the safety and efficacy of a granulocyte-macrophage colony-stimulating factor (GM-CSF)-based immunotherapy administered in patients with resected pancreatic adenocarcino...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181fd271c

    authors: Lutz E,Yeo CJ,Lillemoe KD,Biedrzycki B,Kobrin B,Herman J,Sugar E,Piantadosi S,Cameron JL,Solt S,Onners B,Tartakovsky I,Choi M,Sharma R,Illei PB,Hruban RH,Abrams RA,Le D,Jaffee E,Laheru D

    更新日期:2011-02-01 00:00:00

  • Variceal recurrence, rebleeding, and survival after endoscopic injection sclerotherapy in 287 alcoholic cirrhotic patients with bleeding esophageal varices.

    abstract:OBJECTIVE:This study tested the validity of the hypothesis that eradication of esophageal varices by repeated injection sclerotherapy would reduce recurrent variceal bleeding and death from bleeding varices in a high-risk cohort of alcoholic patients with cirrhosis. SUMMARY BACKGROUND DATA:Although banding of esophage...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000231704.45005.4e

    authors: Krige JE,Kotze UK,Bornman PC,Shaw JM,Klipin M

    更新日期:2006-11-01 00:00:00

  • Short-term surgical outcomes from a randomized controlled trial to evaluate laparoscopic and open D3 dissection for stage II/III colon cancer: Japan Clinical Oncology Group Study JCOG 0404.

    abstract:OBJECTIVE:A randomized controlled trial to confirm the non-inferiority of laparoscopic surgery to open surgery in terms of overall survival was conducted, and short-term surgical outcomes are demonstrated. BACKGROUND:The efficacy and safety outcome of laparoscopic surgery for clinical stages II/III colon cancer underg...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/SLA.0000000000000499

    authors: Yamamoto S,Inomata M,Katayama H,Mizusawa J,Etoh T,Konishi F,Sugihara K,Watanabe M,Moriya Y,Kitano S,Japan Clinical Oncology Group Colorectal Cancer Study Group.

    更新日期:2014-07-01 00:00:00

  • Hyperthermic pelvic perfusion with tumor necrosis factor-α for locally advanced cancers: encouraging results of a phase II study.

    abstract:PURPOSE:To assess the efficacy of isolated pelvic perfusion (IPP) with tumor necrosis factor (TNF)-α and melphalan in patients with locally advanced cancers in the pelvic and groin area requiring mutilating surgery. METHODS:A total of 27 patients were enrolled (carcinoma, n = 17; sarcoma/melanoma, n = 4; and endocrine...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318242ebe7

    authors: Bonvalot S,de Baere T,Mendiboure J,Paci A,Farace F,Drouard-Troalen L,Bonnet L,Hakime A,Bonniaud G,Raynard B,Israel P,Le Cesne A,Eggermont AM,Laplanche A,Muret J

    更新日期:2012-02-01 00:00:00

  • Surgical management of bleeding chronic peptic ulcer. A 10-year prospective study.

    abstract::Analysis of experience with chronic bleeding peptic ulcer in 504 patients, admitted from 1960 to 1971, shows a hospital mortality of 12%. This retrospective review suggested that early endoscopic diagnosis, adequate resuscitation and a policy of early selective surgery was necessary if mortality was to be reduced. Wit...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198401000-00008

    authors: Hunt PS

    更新日期:1984-01-01 00:00:00

  • In-hospital Surgical Delay Does Not Increase the Risk for Perforated Appendicitis in Children: A Single-center Retrospective Cohort Study.

    abstract:OBJECTIVE:To investigate the correlation between in-hospital surgical delay before appendectomy for suspected appendicitis and the finding of perforated appendicitis in children. METHODS:All children undergoing acute appendectomy for suspected acute appendicitis at Karolinska University Hospital, Stockholm, Sweden fro...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001694

    authors: Almström M,Svensson JF,Patkova B,Svenningsson A,Wester T

    更新日期:2017-03-01 00:00:00

  • Renal blood flow and intrarenal distribution of blood flow after decapsulation in the postischemic kidney.

    abstract::Previous reports suggest the value of renal decapsulation in the prevention of renal failure after acute ischemia. It has been suggested that this response is due to a release of "compartmental" pressure resulting in increased blood flow to the decapsulated kidney. Ten dogs were evaluated following 90 minutes of renal...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198004000-00011

    authors: Stothert JC Jr

    更新日期:1980-04-01 00:00:00

  • The Objective Structured Clinical Examination. The new gold standard for evaluating postgraduate clinical performance.

    abstract:OBJECTIVE:The authors determine the reliability, validity, and usefulness of the Objective Structured Clinical Examination (OSCE) in the evaluation of surgical residents. SUMMARY BACKGROUND DATA:Interest is increasing in using the OSCE as a measurement of clinical competence and as a certification tool. However, conce...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199512000-00007

    authors: Sloan DA,Donnelly MB,Schwartz RW,Strodel WE

    更新日期:1995-12-01 00:00:00

  • Comparison of Postoperative Outcomes Between Donation After Circulatory Death and Donation After Brain Death Liver Transplantation Using the Comprehensive Complication Index.

    abstract:OBJECTIVE:To test the total burden of complications in the early postoperative period after liver transplantation (LT) between donation after circulatory death (DCD) and donation after brain death (DBD) grafts with the novel Comprehensive Complication Index (CCI). BACKGROUND:LT is complex surgery and the increasing us...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002419

    authors: Kalisvaart M,de Haan JE,Polak WG,Metselaar HJ,Wijnhoven BPL,IJzermans JNM,de Jonge J

    更新日期:2017-11-01 00:00:00

  • Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters.

    abstract:OBJECTIVE:To determine the long-term results of liver transplantation for hepatocellular carcinoma (HCC) measuring 5 cm or larger treated in a multimodality adjuvant protocol. SUMMARY BACKGROUND DATA:Transplant has been established as a viable treatment of HCC measuring less than 5 cm, but the results for larger tumor...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-200204000-00012

    authors: Roayaie S,Frischer JS,Emre SH,Fishbein TM,Sheiner PA,Sung M,Miller CM,Schwartz ME

    更新日期:2002-04-01 00:00:00

  • Adrenergic control of adipocyte lipolysis in trauma and sepsis.

    abstract::Adipocyte lipolysis and its adrenergic control were studied in vitro from normal patients and those with trauma and sepsis. The adrenergic receptors were studied in terms of their responsiveness, a measure of the postreceptor mechanism, and their sensitivity, a measure of the receptor number or affinity. With early tr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198712000-00010

    authors: Forse RA,Leibel R,Askanazi J,Hirsch J,Kinney JM

    更新日期:1987-12-01 00:00:00

  • Effect of a prior portasystemic shunt on subsequent liver transplantation.

    abstract::Fifteen patients who had a prior portasystemic shunt underwent orthotopic liver transplantation. Shunt types were portacaval in six patients, H-graft mesocaval in six, distal splenorenal in two, and proximal splenorenal in one. Mean blood loss and hospital stay were highest in the portacaval group. Retransplants (two ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198901000-00008

    authors: Brems JJ,Hiatt JR,Klein AS,Millis JM,Colonna JO,Quinones-Baldrich WJ,Ramming KP,Busuttil RW

    更新日期:1989-01-01 00:00:00

  • Surgery for caustic injuries of the upper gastrointestinal tract.

    abstract:BACKGROUND:Surgery is the criterion standard for the treatment of severe burns and of late sequels after ingestion of corrosive agents, but long-term outcome is unknown. METHODS:Patients who underwent surgery between 1987 and 2006, for the treatment of severe caustic burns (group I, n = 268) or of late sequels (group ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182583fb2

    authors: Chirica M,Resche-Rigon M,Bongrand NM,Zohar S,Halimi B,Gornet JM,Sarfati E,Cattan P

    更新日期:2012-12-01 00:00:00

  • Factors Predicting Outcomes After a Total Pancreatectomy and Islet Autotransplantation Lessons Learned From Over 500 Cases.

    abstract:OBJECTIVE:Our objective was to analyze factors predicting outcomes after a total pancreatectomy and islet autotransplantation (TP-IAT). BACKGROUND:Chronic pancreatitis (CP) is increasingly treated by a TP-IAT. Postoperative outcomes are generally favorable, but a minority of patients fare poorly. METHODS:In our singl...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001453

    authors: Chinnakotla S,Beilman GJ,Dunn TB,Bellin MD,Freeman ML,Radosevich DM,Arain M,Amateau SK,Mallery JS,Schwarzenberg SJ,Clavel A,Wilhelm J,Robertson RP,Berry L,Cook M,Hering BJ,Sutherland DE,Pruett TL

    更新日期:2015-10-01 00:00:00

  • A simple test to identify coarctation of the aorta.

    abstract::Despite the widespread recognition of coartation of the aorta there are still many patients in whome the diagnosis is not made. A simple clinical test which is useful in making the diagnosis in infants and adults, is described. It depends upon the differential color changes between fingers and toes after releasing a m...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197611000-00014

    authors: Gerbode F

    更新日期:1976-11-01 00:00:00

  • Multiple cutaneous malignant melanomas with features of primary melanoma.

    abstract::A case report and review of the literature regarding multiple primary melanomas, and a discussion of the histologic differentiation between cutaneous primary melanomas and dermal metastases are presented. This report concerns a patient who, following wide surgical resection of a 1.3 mm thick primary melanoma with sate...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00021

    authors: Unger SW,Wanebo HJ,Cooper PH

    更新日期:1981-02-01 00:00:00

  • Accelerated partial breast irradiation after conservative surgery for breast cancer.

    abstract:OBJECTIVE:To critically review the theoretical and actual risks and benefits of accelerated partial breast irradiation (APBI) after breast-conserving surgery. SUMMARY BACKGROUND DATA:Because of rapid evolution of radiation therapy techniques related to brachytherapy and three-dimensional conformal radiation therapy, A...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/01.sla.0000114219.71899.13

    authors: Kuerer HM,Julian TB,Strom EA,Lyerly HK,Giuliano AE,Mamounas EP,Vicini FA

    更新日期:2004-03-01 00:00:00

  • K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas.

    abstract:OBJECTIVE:To evaluate clinical parameters, presurgical diagnostic tests, histologic findings, and the presence of K-ras oncogene mutations in cystic tumors of the pancreas to determine which best predict malignancy. SUMMARY BACKGROUND DATA:Because presurgical, intraoperative, and final pathologic differentiation is di...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199807000-00012

    authors: Bartsch D,Bastian D,Barth P,Schudy A,Nies C,Kisker O,Wagner HJ,Rothmund M

    更新日期:1998-07-01 00:00:00

  • Five to twenty year followup after surgery for chronic pancreatitis in 148 patients.

    abstract::One-hundred and forty eight patients operated upon for chronic pancreatitis were reviewed retrospectively in 5-20 year followup. Treatment was by drainage of the duct of Wirsung to adefunctionalized jejunal loop, distal pancreatectomy, pancreato-duodenectomy, splanchnicectomy with an operative mortality of 5%. Influen...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197408000-00010

    authors: Leger L,Lenriot JP,Lemaigre G

    更新日期:1974-08-01 00:00:00

  • Transluminal coronary angioplasty during saphenous coronary bypass surgery: a preliminary report.

    abstract::A previously described balloon tipped dilatation catheter has been used during revascularization surgery to dilate lesions which potentially could limit the runoff of the saphenous bypass grafts. A total of 34 lesions were dilated in 25 patients. Restudy of 12 patients (15 lesions) demonstrated positive results and no...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198002000-00017

    authors: Wallsh E,Franzone AJ,Clauss RH,Bruno MS,Steichen F,Stertzer SH

    更新日期:1980-02-01 00:00:00