Effects of theophylline on breathlessness and exercise tolerance in patients with chronic airflow obstruction.

abstract：:The incidence of distal esophageal adenocarcinoma and primary proximal gastric carcinoma has increased substantially in the past 15 years, particularly in North America and in some European countries. Patients with curatively resected cancer consistently have a 10 to 20% 5-year survival rate. Radiation therapy alone s...

journal_title：Chest

authors： Ajani JA

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Patients with COPD are at risk for cardiovascular events. This is attributed to increased systemic inflammation. The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined. METHODS:We a...

journal_title：Chest

authors： Donaldson GC,Hurst JR,Smith CJ,Hubbard RB,Wedzicha JA

更新日期：2010-05-01 00:00:00

abstract：STUDY OBJECTIVES:Significant morbidity and mortality offset the benefits of lung volume reduction surgery (LVRS) for emphysema. By contributing to distal lung collapse, bronchoscopic placement of valved prostheses has the potential to noninvasively replicate the beneficial effects of LVRS. The purpose of this study was...

journal_title：Chest

authors： Snell GI,Holsworth L,Borrill ZL,Thomson KR,Kalff V,Smith JA,Williams TJ

更新日期：2003-09-01 00:00:00

abstract：:A 60-pack-year smoker presented with cough, dyspnea and orthopnea of three months' duration. Spirometry revealed severe reduction in maximal expiratory flow; CT of the chest and bronchoscopy demonstrated expiratory collapse of a mid-tracheal segment, and a presumptive diagnosis of tracheomalacia was made. A right late...

journal_title：Chest

authors： Dunn WF,Hubmayr RD,Pairolero PC,Sheedy PF,Edell ES,Nelson SB

更新日期：1990-04-01 00:00:00

abstract：:Arrhythmias that may accompany myocardial reperfusion have generated significant clinical interest. First, there were concerns, based on animal studies, that high-grade ventricular tachyarrhythmias would pose a serious threat following thrombolytic therapy to treat an evolving myocardial infarction. Second, lower-grad...

journal_title：Chest

authors： Krumholz HM,Goldberger AL

更新日期：1991-04-01 00:00:00

abstract：STUDY OBJECTIVE:To determine if a training session using videotaped metered dose inhaler (MDI) performances can result in high interrater and intrarater reliability of five evaluators assessing MDI technique. DESIGN:Five evaluators (three pharmacists, two pulmonary fellows) were trained to evaluate MDI technique durin...

journal_title：Chest

authors： Gray SL,Nance AC,Williams DM,Pulliam CC

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To determine the utility of inhaled hypertonic saline solution to treat infants hospitalized with viral bronchiolitis. DESIGN:Randomized, double-blind, controlled trial. Fifty-two hospitalized infants (mean +/- SD age, 2.9 +/- 2.1 months) with viral bronchiolitis received either inhalation of epinephrine, 1....

journal_title：Chest

authors： Mandelberg A,Tal G,Witzling M,Someck E,Houri S,Balin A,Priel IE

更新日期：2003-02-01 00:00:00

abstract：:Unresectable carcinoma of the lung has traditionally been recognized as a contraindication to surgery in massive hemoptysis. A 60-year-old man had massive hemoptysis. At surgery an unresectable neoplastic mass invading the mediastinum and great vessels was encountered. Subtotal resection was accomplished using a stapl...

journal_title：Chest

authors： Hargrove WC 3rd,Harken AH

更新日期：1979-08-01 00:00:00

abstract：:To facilitate the studies in cell biology and drug sensitivity of non-small cell lung cancer, cell samples from 55 patients have been used to establish cell lines in culture using a chemically defined medium (ACL-4). A total of 20 cell lines (36 percent) were directly established and characterized: 14 (44 percent) fro...

journal_title：Chest

authors： Masuda N,Fukuoka M,Takada M,Kudoh S,Kusunoki Y

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Whether proadrenomedullin (ProADM) improves the performance of the Risk of Early Admission to ICU (REA-ICU) score in predicting early, severe community-acquired pneumonia (ESCAP) has not been demonstrated. METHODS:Secondary analysis was completed of the original data from 877 consecutive patients with commu...

journal_title：Chest

authors： Renaud B,Schuetz P,Claessens YE,Labarère J,Albrich W,Mueller B

更新日期：2012-12-01 00:00:00

abstract：:This report describes a 25-year follow-up of angiographically proven bilateral functioning Vineberg grafts. This represents the longest angiographic follow-up found in the literature. The relevance of these grafts in present-day revascularization procedures is discussed. ...

journal_title：Chest

authors： Hughes MM

更新日期：1997-03-01 00:00:00

abstract：STUDY OBJECTIVES:Pneumonia during chemotherapy-induced leukocytopenia is a major cause of overall treatment failure in patients with hematologic malignancies. To improve outcome in these high-risk patients, early diagnosis of pulmonary infiltrates and institution of adequate antimicrobial treatment are mandatory. To id...

journal_title：Chest

authors： Kiehl MG,Ostermann H,Thomas M,Birkfellner T,Kienast J

更新日期：1997-11-05 00:00:00

abstract：BACKGROUND:Disease-specific patient-reported outcome (PRO) instruments are important in assessing the impact of disease and treatment. The Pulmonary Arterial Hypertension-Symptoms and Impact Questionnaire is the first instrument for quantifying pulmonary arterial hypertension (PAH) symptoms and impacts developed accord...

journal_title：Chest

authors： Chin KM,Gomberg-Maitland M,Channick RN,Cuttica MJ,Fischer A,Frantz RP,Hunsche E,Kleinman L,McConnell JW,McLaughlin VV,Miller CE,Zamanian RT,Zastrow MS,Badesch DB

更新日期：2018-10-01 00:00:00

abstract：:Radiation therapy has been the usual initial treatment for mediastinal seminoma in the past. However, 25 to 40 percent of patients are not cured by this therapy, and other therapy is needed. Review of case reports show that vinblastine, bleomycin, and cis-platinum are effective therapy for metastatic disease, advanced...

journal_title：Chest

authors： Clamon GH

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...

journal_title：Chest

authors： Sato M,Saito Y,Endo C,Sakurada A,Feller-Kopman D,Ernst A,Kondo T

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Both pulmonary hypertension and pulmonary overflow are associated with functional and structural changes of the pulmonary arterial wall. Current techniques to evaluate the pulmonary vasculature neglect the pulsatile nature of pulmonary flow. STUDY OBJECTIVES:To determine whether the dynamic properties of th...

journal_title：Chest

authors： Berger RM,Cromme-Dijkhuis AH,Hop WC,Kruit MN,Hess J

更新日期：2002-08-01 00:00:00

abstract：:Bitolterol mesylate (WIN 37284) is alpha-[tert-butylaminomethyl]-3,4-dihydroxybenzyl alcohol 3,4-di(p-toluate) methanesulfonate, a diester sympathomimetic amine bronchodilator. Bitolterol mesylate represents a new concept in sympathomimetic amine therapy. It is "prodrug" which is inactive until altered in the body. Th...

journal_title：Chest

authors： Kass I,Mingo TS

更新日期：1980-08-01 00:00:00

abstract：STUDY OBJECTIVE:Lung transplantation is now available for patients with cystic fibrosis (CF) and end-stage lung disease. While pulmonary graft function is often considered the major priority following transplantation, the nonpulmonary complications of this systemic disease also continue. We examined the GI complication...

journal_title：Chest

authors： Gilljam M,Chaparro C,Tullis E,Chan C,Keshavjee S,Hutcheon M

更新日期：2003-01-01 00:00:00

abstract：:We tested the response characteristics of a dual transcutaneous (tc) PO2/PCO2 monitoring system in healthy subjects who breathed various gas mixtures, and we compared steady-state tc readings to simultaneous arterial blood gas analysis in 20 stable respiratory outpatients. The electrodes were simple to apply, required...

journal_title：Chest

authors： Kesten S,Chapman KR,Rebuck AS

更新日期：1991-05-01 00:00:00

abstract：:We report a case of primary pulmonary hypertension in an adult man with CD8/T-cell large granulocyte leukemia. Successful treatment of his leukemia with cladribine resulted in dramatic and sustained improvement of his pulmonary hypertension. ...

journal_title：Chest

authors： Rossoff LJ,Genovese J,Coleman M,Dantzker DR

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Epidemiologic investigations of acute lung injury (ALI) and ARDS have focused on mechanically ventilated patients in ICUs, and have reported high mortality rates. We sought to determine the incidence and lethality of these syndromes in the respiratory isolation areas of general wards, a non-ICU setting that ...

journal_title：Chest

authors： Quartin AA,Campos MA,Maldonado DA,Ashkin D,Cely CM,Schein RMH

更新日期：2009-02-01 00:00:00

abstract：:Unidirectional endobronchial valves, originally studied for potential treatment of emphysema, have emerged as a useful intervention for patients with persistent air leak from the lung. The procedure is accomplished via bronchoscopy in a patient who already has a chest tube in place for management of the air leak. It u...

journal_title：Chest

authors： Kovitz KL,French KD

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Cigarette smoking is associated with worse symptoms in asthma and abnormal segmental airways in healthy subjects. We tested the hypothesis that current symptom control in smokers with asthma is associated with altered segmental airway dimensions measured by CT scan. METHODS:In 93 subjects with mild, moderat...

journal_title：Chest

authors： Thomson NC,Chaudhuri R,Spears M,Messow CM,MacNee W,Connell M,Murchison JT,Sproule M,McSharry C

更新日期：2015-03-01 00:00:00

abstract：:The effect of smoking three cigarettes in rapid succession on maximal and partial expiratory flow rates was studied in ten healthy smokers. The mean decrease in maximal midexpiratory flow and partial midexpiratory and end-expiratory flow was statistically significant. The response was maximal after the first cigarette...

journal_title：Chest

authors： Hamosh P,Taveira Da Silva AM

更新日期：1977-11-01 00:00:00

abstract：:The clinical and histopathologic features of pulmonary amyloidosis were reviewed in 22 patients with systemic amyloidosis who came to autopsy. Eleven of 12 patients (92 percent) with primary amyloidosis had prominent interalveolar amyloid deposits. Symptoms attributable to these deposits were found in four cases (33 p...

journal_title：Chest

authors： Celli BR,Rubinow A,Cohen AS,Brody JS

更新日期：1978-11-01 00:00:00

abstract：:Sacrococcygeal teratoma is rarely diagnosed in adults. Pulmonary mass as the presenting clinical form of the malignant variety of this germ-cell tumor is exceptional. We report herein such a case with the noticeable peculiarity of showing the air meniscus sign on chest roentgenographic examination. ...

journal_title：Chest

authors： Roig J,Aguilar X,Maestre J,Domingo C,Morera J

更新日期：1991-08-01 00:00:00

abstract：:Electrocardiogram changes and pharmacologic responses were studied in 28 cases of brain death. Cardiac activity in this condition is possibly determined by the dynamic balance between the depressant action of hypothermia and the stimulating action of the sympathetic nervous system (without any vagal or central influen...

journal_title：Chest

authors： Drory Y,Ouaknine G,Kosary IZ,Kellermann JJ

更新日期：1975-04-01 00:00:00

abstract：:Pulmonary disease due to talc, a group of hydrous magnesium silicates, is almost exclusively encountered after occupational exposure. One form of this rare disorder is talc granulomatosis. In varying degrees, hypercalcemia is typical of granulomatous disease but has not yet been reported in talcosis. We report the cas...

journal_title：Chest

authors： Woywodt A,Schneider W,Goebel U,Luft FC

更新日期：2000-04-01 00:00:00

abstract：:We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...

journal_title：Chest

authors： Laube BL,Links JM,LaFrance ND,Wagner HN Jr,Rosenstein BJ

更新日期：1989-04-01 00:00:00

abstract：STUDY OBJECTIVES:To describe four patients having total anomalous pulmonary venous connection with an intrapulmonary vertical vein, rendering difficulty in diagnosis and surgery. SETTING:a tertiary referral center. PATIENTS AND METHODS:By reviewing medical records, 4 of 25 patients with right atrial isomerism and tot...

journal_title：Chest

authors： Wang JK,Chiu IS,How SW,Wu MH,Wu FF,Hung CR,Lue HC

更新日期：1996-11-01 00:00:00