Clinically important immunological processes in acute and fulminant hepatitis, mainly due to hepatitis B virus.

abstract：:An usually high rate of both tuberculosis infection and active disease is reported in 11 of 38 nursery children in contact with a case of smear positive pulmonary tuberculosis, emphasising the susceptibility of young children to this disease. This report also underlines some important principles in case finding and di...

journal_title：Archives of disease in childhood

authors： Milburn HJ,Gibilaro J,Atkinson H,Heathcock R

更新日期：2000-05-01 00:00:00

abstract：STUDY OBJECTIVES:To present diagnosis and treatment modalities of children with interstitial lung disease associated with frequent or rare surfactant protein C gene (SFTPC) mutation. PATIENTS:Twenty-two children with chronic lung disease associated with SFTPC mutation in a heterozygous form. RESULTS:Mutations located...

journal_title：Archives of disease in childhood

authors： Thouvenin G,Abou Taam R,Flamein F,Guillot L,Le Bourgeois M,Reix P,Fayon M,Counil F,Depontbriand U,Feldmann D,Pointe HD,de Blic J,Clement A,Epaud R

更新日期：2010-06-01 00:00:00

abstract：:The availability of resource (staffing and services) in all 21 paediatric diabetes services in Yorkshire and Humber Strategic Health Authority, UK was surveyed and this information was combined with demographic and clinical data on 2683 children and young people with diabetes (aged 0-23 years) to assess whether level ...

journal_title：Archives of disease in childhood

authors： Harron KL,McKinney PA,Feltbower RG,Holland P,Campbell FM,Parslow RC

更新日期：2012-06-01 00:00:00

abstract：:19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors w...

journal_title：Archives of disease in childhood

authors： Rizzoni G,Malekzadeh MH,Pennisi AJ,Ettenger RB,Uittenbogaart CH,Fine RN

更新日期：1980-07-01 00:00:00

abstract：:Two infants presented with a salt-losing syndrome, the presenting features of which were subtle. One case appeared to be transient. Deficient production of aldosterone was shown by plasma renin activity and plasma aldosterone profile. Gas chromatography-mass spectrometry of urine indicated a defect in 18-dehydrogenati...

journal_title：Archives of disease in childhood

authors： Milla PJ,Trompeter R,Dillon MJ,Robins D,Shackleton C

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Following recent reports of increased numbers of adolescents being diagnosed with the adult or type 2 form of diabetes we aimed to describe the prevalence of both type 2 and other forms of diabetes in an urban population of children and young people in northern England. METHODS:A hospital based cro...

journal_title：Archives of disease in childhood

authors： Feltbower RG,McKinney PA,Campbell FM,Stephenson CR,Bodansky HJ

更新日期：2003-08-01 00:00:00

abstract：:Forty-seven cases of prune belly syndrome in children born between 1948 and 1977 are described. They have been classified into three groups according to the state of the urinary tract in the neonatal period. The results achieved in these cases form the basis of our present management. In group I, the most severely aff...

journal_title：Archives of disease in childhood

authors： Woodhouse CR,Ransley PG,Innes-Williams D

更新日期：1982-11-01 00:00:00

abstract：:Metabolic rhythms were studied over 24 hours in eight adolescent diabetic patients during treatment with porcine insulin and after transfer to human insulin. Despite an increase in dose with human insulin no significant changes were found in fasting blood glucose, 24h mean blood glucose, or glycosylated haemoglobin co...

journal_title：Archives of disease in childhood

authors： Hocking MD,Crase J,Rayner PH,Nattrass M

更新日期：1986-04-01 00:00:00

abstract：:Clinical observations and findings on imaging are reported in six newborns with symmetrical thalamic lesions (STL). In three cases the diagnosis was confirmed by postmortem examination. Characteristic observations in this series and 17 previously reported cases include no evidence of perinatal asphyxia, high incidence...

journal_title：Archives of disease in childhood

authors： Eicke M,Briner J,Willi U,Uehlinger J,Boltshauser E

更新日期：1992-01-01 00:00:00

abstract：AIMS:To test the hypothesis that oxygen free radicals are mediators of excessive protein permeability in steroid responsive nephrotic syndrome. DESIGN:Case control study. SUBJECTS: PATIENTS:20 children with steroid responsive nephrotic syndrome; controls: 20 children admitted for elective surgery. SETTING:The paedi...

journal_title：Archives of disease in childhood

authors： Kinra S,Rath B,Kabi BC

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To examine the value of neurodevelopmental examination, fragile X testing, iron studies, and other screening procedures in children with mild to moderate learning difficulties. DESIGN:A cross sectional case-control study. SUBJECTS:A 34% random sample (n = 130) of children with mild to moderate learning diff...

journal_title：Archives of disease in childhood

authors： Corrigan N,Stewart M,Scott M,Fee F

更新日期：1997-03-01 00:00:00

abstract：:Thirty jaundiced neonates with diarrhoea who were being treated with phototherapy and 30 matched control infants were studied to try and find out the cause of the diarrhoea. Faecal osmolality and electrolyte concentrations were measured, which gave clear evidence that the diarrhoea arose from intestinal secretion. Rec...

journal_title：Archives of disease in childhood

authors： De Curtis M,Guandalini S,Fasano A,Saitta F,Ciccimarra F

更新日期：1989-08-01 00:00:00

abstract：:Ten patients with biotinidase deficiency were studied. Clinical findings at presentation varied with dermatological signs (dermatitis and alopecia), neurological abnormalities (fits, hypotonia, and ataxia), and recurrent infections being the most common features, although none of these occurred in every case. Biochemi...

journal_title：Archives of disease in childhood

authors： Wastell HJ,Bartlett K,Dale G,Shein A

更新日期：1988-10-01 00:00:00

abstract：:The first case of collagenous colitis in a child with protracted watery diarrhoea and abdominal pain is reported. Small bowel investigations and the macroscopic appearances were normal, but histological examination of the colon showed collagenous colitis. Steroids temporarily relieved the diarrhoea and induced transie...

journal_title：Archives of disease in childhood

authors： Perisic VN,Kokai G

更新日期：1989-06-01 00:00:00

abstract：:Obesity is becoming a common clinical headache for child health professionals, as the increase in professional and media concern has not been matched by effective clinical solutions. Added to this is considerable confusion about both the definitions of obesity and about which groups of children and adolescents actuall...

journal_title：Archives of disease in childhood

authors： Viner R,Nicholls D

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The Coventry Consensus in 1998 recommended a single height measurement of all children at school entry or around the age of 5 years and prompt referral of children with height <0.4th centile for further assessment, in order to identify undetected and treatable asymptomatic growth disorders. AIM:To determine...

journal_title：Archives of disease in childhood

authors： Banerjee S,Morgan RJ,Rees SA,Latif AH

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To examine information needs and preferences of parents regarding food allergy. DESIGN:Qualitative study including in-depth semi-structured interviews and focus group discussions. Data were audio-recorded, transcribed verbatim and analysed using the constant comparative method, aided by participant checking ...

journal_title：Archives of disease in childhood

authors： Hu W,Grbich C,Kemp A

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Despite immunisation, antibiotics and intensive care management, infection with Streptococcus pneumoniae remains a major cause of morbidity and mortality in children. The WHO currently recommends vaccinating infants with either a 3+0 schedule (6 weeks, 3-4 and 4-6 months of age) or 2+1 schedule (2 doses be...

journal_title：Archives of disease in childhood

authors： Zimmermann P,Perrett KP,Berbers G,Curtis N

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Congenital lymphoedema is a lifelong condition that has detrimental physical and psychosocial outcomes for young patients and burdensome treatment responsibilities that may hamper patients' motivation for self-management. There is limited research from the perspective of young people with primary lymphoedema...

journal_title：Archives of disease in childhood

authors： Hanson CS,Newsom J,Singh-Grewal D,Henschke N,Patterson M,Tong A

更新日期：2018-07-01 00:00:00

abstract：:Lung function measurements with and without a disposable bacterial filter were compared in 60 children. Although statistically significant, the reduction of lung function measurements caused by using bacterial filters was small and clinically irrelevant (2-4% of predicted for forced expiratory volume in one second and...

journal_title：Archives of disease in childhood

authors： Kamps AW,Vermeer K,Roorda RJ,Brand PL

更新日期：2001-10-01 00:00:00

abstract：:Three children with cystic fibrosis developed steatorrhoea unresponsive to changes in pancreatic supplements. The final diagnoses were chronic giardiasis, stagnant loop syndrome, and Crohn's disease. Refractory intestinal symptoms in cystic fibrosis merit further investigation. ...

journal_title：Archives of disease in childhood

authors： Baxter PS,Dickson JA,Variend S,Taylor CJ

更新日期：1988-12-01 00:00:00

abstract：:Parent reported pulse rates could provide important information on a child's clinical condition. The agreement between the parent's measurement of their child's pulse and a pulse oximeter was assessed following a brief educational intervention. Parents can be taught to measure the pulse of school age children, but hav...

journal_title：Archives of disease in childhood

authors： White J,Shepperd S,Yudkin P,Harnden A,Mant D

更新日期：2004-03-01 00:00:00

abstract：:We describe a prospective study in which we investigated why children fail to get vaccinated against whooping cough, including an assessment of the attitudes of parents and professionals and the impact of different views of the contraindications. There was considerable disagreement among the professionals on the inter...

journal_title：Archives of disease in childhood

authors： Stevens D,Baker R,Hands S

更新日期：1986-04-01 00:00:00

abstract：:During June and July 1977 5 junior boys in a boarding school for 800 pupils became ill with a mild infection caused by Coxsackie B1. The school had been taking part in a vaccine trial, and paired blood samples had been taken from new entrants in October 1976 and October 1977. 18% of the boys susceptible to the infecti...

journal_title：Archives of disease in childhood

authors： Hoskins TW,Davies JR,Smith AJ,Collingham K,Chamberlain RN

更新日期：1979-04-01 00:00:00

abstract：:Interferon is becoming the standard treatment in adults for chronic hepatitis C. Twenty one children with histologically proved chronic hepatitis C (10 boys, range 2.5-13 years), who were otherwise healthy, were enrolled in a randomised controlled study to test their response to interferon alfa. Eleven children were t...

journal_title：Archives of disease in childhood

authors： Iorio R,Pensati P,Porzio S,Fariello I,Guida S,Vegnente A

更新日期：1996-02-01 00:00:00

abstract：AIM:To assess the value and safety of fasts for investigating hypoglycaemia or suspected metabolic disease. STUDY DESIGN:Review of all diagnostic fasts performed over a 2.5 year period. SETTING:The neonatal intensive care unit and programmed investigation unit at a tertiary referral centre for endocrinology and metab...

journal_title：Archives of disease in childhood

authors： Morris AA,Thekekara A,Wilks Z,Clayton PT,Leonard JV,Aynsley-Green A

更新日期：1996-08-01 00:00:00

abstract：:Blood lead concentrations and body iron status were investigated in 279 children. Blood lead concentrations showed no increase during iron depletion phase (stage I) but markedly increased from the phase of iron deficient erythropoiesis (stage II). Increased blood lead concentrations in anaemic subjects significantly d...

journal_title：Archives of disease in childhood

authors： Choi JW,Kim SK

更新日期：2003-09-01 00:00:00

abstract：:Three children with Reye's syndrome are described. One child died, the second had mild and transient illness, and the third had recurrent episodes. In all 3 children a muscle biopsy showed pronounced infiltration of the myofibres with fat microdroplets as shown by the oil red O stain and by electron microscopical exam...

journal_title：Archives of disease in childhood

authors： Shapira Y,Deckelbaum R,Statter M,Tennenbaum A,Aker M,Yarom R

更新日期：1981-04-01 00:00:00

abstract：:Doppler ultrasound measurements of pulmonary blood flow in 20 babies with severe respiratory distress syndrome treated in a randomised controlled trial of surfactant replacement showed that the immediate improvement of oxygenation was not associated with a significant increase in pulmonary blood flow. Reduction in ven...

journal_title：Archives of disease in childhood

authors： Halliday HL,McCord FB,McClure BG,Reid MM

更新日期：1989-01-01 00:00:00

abstract：AIMS:To investigate how parents report children's respiratory sounds on video compared to a clinical "gold standard". METHODS:Five clinicians agreed on 10 video clips of children with audible breathing. These responses were the "gold standard". The clips were shown to parents of children: (a) with asthma/wheeze; (b) w...

journal_title：Archives of disease in childhood

authors： Cane RS,McKenzie SA

更新日期：2001-01-01 00:00:00