Abstract：
OBJECTIVE:The diagnostic criteria of chronic fatigue syndrome (CFS) define a heterogeneous population composed of several subgroups. Past efforts to identify subgroup markers have met with mixed success. This study was designed to examine natural killer cell activity (NKCA) as a potential subgroup marker by comparing the clinical presentations of CFS patients with and without clinically reduced NKCA. METHODS:Forty-one female CFS patients were classified into having either low or normal NKCA levels. These subgroups were then compared on objective measures of cognitive functioning and subjective assessments of fatigue, vigor, cognitive impairment, and daytime dysfunction. RESULTS:Relative to CFS patients in the normal-NKCA subgroup, low-NKCA patients reported less vigor, more daytime dysfunction, and more cognitive impairment. In addition, low-NKCA patients performed less on objective measures of cognitive functioning relative to normal-NKCA patients. CONCLUSIONS:The results are offered as preliminary evidence in support of using NKCA as an immunological subgroup marker in CFS. Findings are also discussed in terms of known associations between dysregulated immune functions, somatic symptoms, and psychological stress.
journal_name
J Psychosom Resjournal_title
Journal of psychosomatic researchauthors
Siegel SD,Antoni MH,Fletcher MA,Maher K,Segota MC,Klimas Ndoi
10.1016/j.jpsychores.2006.03.001subject
Has Abstractpub_date
2006-06-01 00:00:00pages
559-66issue
6eissn
0022-3999issn
1879-1360pii
S0022-3999(06)00097-3journal_volume
60pub_type
杂志文章abstract：BACKGROUND:We examined whether a program combining cognitive-behavioural therapy (CBT), vestibular rehabilitation (VR) and psychoeducation is equally effective in improving psychometric measures in patients with dizziness independent of a balance deficit. Measures of patients with dizziness only (DO) were compared to t...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2017.11.020
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:Medically unsubstantiated 'intolerances' to foods, chemicals and environmental toxins are common and are frequently discussed in the media. Idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) is one such condition and is characterized by symptoms that are attributed to exposure...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jpsychores.2012.12.002
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:Atrial fibrillation (AF) is associated with a varying symptom burden, which ranges from completely unawareness to disabling conditions. The present cross-sectional study tried to assess if neuroticism is associated with a greater degree of perception of AF related symptoms. METHODS:162 patients who were cons...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2020.110225
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:The current study focused on the role of trait mindfulness in asthma-related quality of life (QoL) and asthma control in adolescent asthma patients. Furthermore, potential underlying mechanisms (general and asthma-specific stress) of this relationship were investigated. METHODS:In this cross-sectional study,...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2017.06.014
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:It is hypothesized that somatic symptom alleviation is a significant predictor of overall outcome in depressed primary care patients. METHODS:Depressed primary care patients (N=205) meeting DSM-IV-TR criteria received open-label antidepressant therapy. The primary symptom measurement tool used was the 17-it...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2005.09.010
更新日期：2006-03-01 00:00:00
abstract：:Cardiovascular and other responses of stress of subjects considered to be at risk for coronary heart disease (CHD) were studied in order to evaluate two hypothesized pathways in the link between CHD risk factors and the disease process. Forty-seven male subjects with and without a parental history of CHD and with eith...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(82)90013-7
更新日期：1982-01-01 00:00:00
abstract：:The predictive validity of subjects' self-reports of the severity of four groups of symptoms associated with the premenstrual syndrome (PMS) was assessed by canonical correlation of retrospective self-reports of usual symptom severities with prospectively obtained symptom severity scores from the next two cycles. Pros...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(87)90075-4
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Multiple chemical sensitivity (MCS) is characterized by a variety of symptoms in response to nontoxic concentrations of chemicals. To further test a laboratory model of MCS based on symptom learning, we used a stronger respiratory challenge in this study than in previous studies to induce symptoms (20% CO(2)-...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2009.03.009
更新日期：2010-01-01 00:00:00
abstract：:The effects of the resistance resources of personality hardiness, exercise, and social support, taken singly and in combination, on concurrent and prospective levels, and probability of illness were studied. In 1980, 85 male business executives identified as high in stressful events were tested for the three resistanc...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(85)90086-8
更新日期：1985-01-01 00:00:00
abstract：:Due to the fact that oral contraceptives (OCs) can alter the pain threshold and since evidence of possible concomitant changes in the cardiovascular response to pain is still missing, an investigation of the response of heart rate (HR), blood pressure (BP), and systolic time interval (STI) to ischemic pain in OC users...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(81)90113-6
更新日期：1981-01-01 00:00:00
abstract：OBJECTIVE:Multiple physical symptoms not attributable to known organic disease are common in all medical fields and associated with major personal and social consequences. This study investigated multiple physical symptoms according to the construct of bodily distress syndrome (BDS) and associated individual characteri...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2020.109941
更新日期：2020-01-28 00:00:00
abstract：:The Pittsburgh Sleep Quality Index (PSQI) measures sleep quality and disturbance retrospectively over a 1-month period using self-reports. Although the PSQI has been used in a variety of populations, published psychometric data are limited. The goal of this study was to examine psychometric properties of the PSQI amon...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(97)00298-5
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:This semiprospective case-control study was performed to investigate the relationship between harmony-seeking personality and the occurrence of prostate cancer. METHODS:Out of 217 consecutive participants admitted to hospital for biopsy, 86 and 81 were classified into the case and control groups, respectivel...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2005.04.006
更新日期：2005-09-01 00:00:00
abstract：:The purpose of the present study was to analyze the factor structure of the Coping Strategies Questionnaire (CSQ). In order to find factors that are reproducible across samples and to evaluate their relationship to pain, disability, and depressive mood, the subjects used were a group of 224 patients with congenital co...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(95)00645-1
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVES:Glandular fever is associated with an approximate fivefold increase in fatigue at 6 months. Reduced levels of fitness and illness beliefs may be important predictors of fatigue following glandular fever. We therefore developed a brief psycho-educational intervention aimed at improving recovery from infectiou...
journal_title：Journal of psychosomatic research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0022-3999(03)00370-2
更新日期：2004-07-01 00:00:00
abstract：:A total of fifty-three female patients suffering from urinary urgency and urge incontinence completed a bladder re-training programme which comprised behavioural and biofeedback treatment components. The psychological status of patients prior to treatment and at eighteen-month follow-up was compared. The role of clini...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(86)90103-0
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to test relations of physical self-concept and self-efficacy with voluntary physical activity in preadolescents enrolled in an after-school physical activity program. METHODS:Participants in the 2003 (n=41) and 2005 (n=84) versions of the Youth Fit For Life protocol and the control group (n=...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2006.04.009
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:Eating disturbances and aspects of psychological control are both repeatedly cited as significant correlates of metabolic control in diabetes mellitus (DM), yet such findings are typically discussed in separate literatures and have been criticized for overreliance on outdated constructs of psychological control...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(01)00243-4
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:Fear of progression (FoP) is a frequent symptom among cancer patients, but data among hematological cancer survivors are scarce. Furthermore, theory assumes that FoP serves as link between bodily symptoms and different aspects of quality of life. However, this model has not been tested with the bodily symptom...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2019.109844
更新日期：2019-12-01 00:00:00
abstract：:Two very different assumptions about the principles of blood pressure reactivity lead to quite different notions about hypertensive/normotensive behaviour. Both are referred to as the Law of Initial Value (LIV). Subsequent confusion about blood pressure reactivity vs resting level partly explains a number of inconsist...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(88)90053-0
更新日期：1988-01-01 00:00:00
abstract：:In order to explore hypochondriacal concerns in patients with Chronic Airflow Obstruction (CAO) the authors administered the Illness Attitude Scales and the somatization, anxiety, depression and anger-hostility scales of the Hopkins Symptom Checklist to 50 patients with CAO and to matched family practice patients. Som...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(87)90036-5
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Modern health worries (MHW) are concerns about health risks from features of modern life (e.g. additives in food, contaminated water supply, drug resistant bacteria, etc.). We investigated the role of MHW for care seeking for all purposes at the general practitioner (GP) and studied the role of neuroticism, s...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2012.07.007
更新日期：2012-10-01 00:00:00
abstract：:Governmental agencies do not systematically investigate the presence of daytime sleepiness as a determinant of driving accidents. We surveyed automobile drivers traveling on summer vacations and driving long distances on a European highway. We evaluated their subjective daytime sleepiness while driving and any sleep d...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(96)00127-4
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVES:To compare the frequency of anxiety/depressive symptoms and use of anxiolytic-hypnotics/antidepressants in smokers with and without COPD and to identify characteristics associated with having unmedicated symptoms. METHODS:Cross-sectional analysis of ambulatory, current/former smokers ≥10 pack years enrolled...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2019.01.002
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to examine the behavioral and psychological responses of pregnant women during the 2003 severe acute respiratory syndrome (SARS) outbreak in Hong Kong. METHODS:Ethnographic interviews were first conducted to identify the common psychological and behavioral responses to the ou...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2006.08.005
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to examine the relationship between alexithymia and perinatal depressive symptoms and the stability of the alexithymia construct in a sample of low-income, predominantly Latina women during pregnancy and the early postpartum period. METHODS:Seventy-seven pregnant women completed...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2006.09.012
更新日期：2007-02-01 00:00:00
abstract：:The relation of stress and family environment to symptom severity in children with atopic dermatitis (AD) was examined. Forty-four children with severe AD and their families completed questionnaires measuring life events, chronic everyday problems and family environment. Measures of symptom severity were collected dur...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(87)90016-x
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Cannabis is a widely used substance that may be becoming more socially accepted, legally tolerated, and utilized by younger individuals. This review explores the relationship between cannabis and the onset of psychosis as well as the policy ramifications of current research. METHOD:This article synthesizes p...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,评审
doi：10.1016/j.jpsychores.2010.04.002
更新日期：2010-12-01 00:00:00
abstract：:Despite that burnout presents a serious burden for modern society, there are no diagnostic criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there is a need to dispose of a burnout biomarker. Epigenetic studies suggest that DNA methylation is a possible mediator linking indiv...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,评审
doi：10.1016/j.jpsychores.2016.11.005
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:Heart failure (HF) markedly diminishes an individual's quality of life. However, little is known about how psychosocial functioning is related to heart failure physical symptom expression (e.g., chest pain or heaviness, shortness of breath) on a day-to-day basis. METHODS:Fifty-eight HF patients completed dai...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/S0022-3999(03)00041-2
更新日期：2004-01-01 00:00:00
