[Lipid profile and nutrition counseling effects in adolescents with family history of premature coronary artery disease].

Abstract:

OBJECTIVE:To assess lipid profile and nutritional parameters from adolescents with family history of premature coronary artery disease (CAD) and assess the effects of nutritional counseling. METHODS:The study included 48 adolescents of both gender and with ages ranging from 10 and 19 years old (case group, n=18; control group, n=30). RESULTS:Offspring of young individuals with coronary artery disease showed higher values of total cholesterol (189 +/- 30 vs. 167 +/- 26 mg/dl, p < 0.01), LDL-C (144 +/- 20 vs. 100 +/- 27 mg/dl, p < 0.001) and apoB (80 +/- 15 vs. 61 +/- 18 mg/dl, p = 0.001) and lower values of HDL-C (45 +/- 9 vs. 51 +/- 13 mg/dl, p < 0.02) than control young individuals. Differences were not found for triglycerides and apoA-I. With a dietotherapeutic counseling, we obtained a reduction in alimentary consumption of saturated fatty acids (pre: 15.5 +/- 4.7% vs. post: 6.6 +/- 3.7%, p = 0.003) and an improvement in lipid profile: TC (-8%, p = 0.033), LDL-C (-18.2%, p = 0.001), TG (-53%, p = 0.002) rates in offspring of premature CAD patients who showed hyperlipidemia. CONCLUSION:The presence of dyslipidemia was more prevalent among offspring adolescents of premature CAD patients, but it was responsive to nutritional intervention.

journal_name

Arq Bras Cardiol

authors

Mendes GA,Martinez TL,Izar MC,Amancio OM,Novo NF,Matheus SC,Bertolami MC,Fonseca FA

doi

10.1590/s0066-782x2006000500006

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

361-5

issue

5

eissn

0066-782X

issn

1678-4170

pii

S0066-782X2006000500006

journal_volume

86

pub_type

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