Abstract:
:The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information archives and freely distributes high-throughput molecular abundance data, predominantly gene expression data generated by DNA microarray technology. The database has a flexible design that can handle diverse styles of both unprocessed and processed data in a Minimum Information About a Microarray Experiment-supportive infrastructure that promotes fully annotated submissions. GEO currently stores about a billion individual gene expression measurements, derived from over 100 organisms, submitted by over 1500 laboratories, addressing a wide range of biological phenomena. To maximize the utility of these data, several user-friendly web-based interfaces and applications have been implemented that enable effective exploration, query, and visualization of these data at the level of individual genes or entire studies. This chapter describes how data are stored, submission procedures, and mechanisms for data retrieval and query. GEO is publicly accessible at http://www.ncbi.nlm.nih.gov/projects/geo/.
journal_name
Methods Enzymoljournal_title
Methods in enzymologyauthors
Barrett T,Edgar Rdoi
10.1016/S0076-6879(06)11019-8subject
Has Abstractpub_date
2006-01-01 00:00:00pages
352-69eissn
0076-6879issn
1557-7988pii
S0076-6879(06)11019-8journal_volume
411pub_type
杂志文章,评审abstract::The Omega class of cytosolic glutathione transferases was initially recognized by bioinformatic analysis of human sequence databases, and orthologous sequences were subsequently discovered in mouse, rat, pig, Caenorhabditis elegans, Schistosoma mansoni, and Drosophila melanogaster. In humans and mice, two GSTO genes h...
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journal_title:Methods in enzymology
pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章,评审
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