Abstract:
:Matings between mice carrying the heterozygous autosomal gene Steel produce 25% homozygous Sl/Sld mutants having agametic gonads composed of somatic tissue alone. Mutants show a normal 1:1 male:female sex ratio and gonadal sex corresponds to genotypic sex. Gonads from both normal and mutant male and female fetuses were obtained on a daily basis from the twelfth day of gestation to birth and morphometrically evaluated for determination of the quantitative expression of XY and XX chromosomal combinations on growth of gonadal somatic tissue. Growth of testicular soma was found to be independent of a germ cell influence throughout the entire course of gestation whereas a germ cell influence on growth of ovarian gonadal soma was apparent from day 18 and thereafter. By birth, testicular somatic growth displayed a ten-fold increase over that of the ovary. These results suggest that early gonadal somatic growth is independent of a germ cell influence. The significant impact of a Y-chromosomal influence on gonadal somatic growth may suggest that male-specific gene product(s) regulate growth as well as differentiation of the somatic elements of the fetal testis.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
McCoshen JAdoi
10.1016/0002-9378(83)90319-8subject
Has Abstractpub_date
1983-02-15 00:00:00pages
469-73issue
4eissn
0002-9378issn
1097-6868pii
0002-9378(83)90319-8journal_volume
145pub_type
杂志文章abstract:BACKGROUND:The health and economic benefits of paid parental leave have been well-documented. In 2016, the American College of Obstetricians and Gynecologists released a policy statement about recommended parental leave for trainees; however, data on adoption of said guidelines are nonexistent, and published data on pa...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2018.04.017
更新日期:2018-08-01 00:00:00
abstract::During a 12-year period, 254 cases of eclampsia were managed at this center. Eighty patients (32%) did not have edema, 58 (23%) had "relative hypertension," and 49 (19%) did not have proteinuria at the time of convulsions. Eclampsia developed at less than or equal to 20 weeks in 6 patients and beyond 48 hours post par...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(90)91123-t
更新日期:1990-09-01 00:00:00
abstract::X-ray evaluation of the pelvis plays a pivotal role in selecting term breech presentation for a possible trial of labor. Even minimal degrees of disproportion may have disastrous consequences for the aftercoming head. Our evaluation of x-ray pelvimetry by computerized tomography scanning suggests it is probably more a...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(85)90695-7
更新日期:1985-12-15 00:00:00
abstract::The effect of stress during labor on the plasma concentration of cortisol, unconjugated estriol, and human chorionic somatomammotropin was studied in 15 healthy primiparous women. According to the method of pain relief the parturients were divided into two groups. One group was given continuous epidural analgesia and ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(79)90650-1
更新日期:1979-07-15 00:00:00
abstract:OBJECTIVE:Our purpose was to determine the usefulness of deoxyribonucleic acid ploidy and S-phase fraction as prognostic factors in patients with cervical cancer. STUDY DESIGN:Paraffin-embedded tumor specimens were obtained from 123 patients with cervical cancer (mean age 51 years, range 21 to 87 years). The mean foll...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(94)90394-8
更新日期:1994-12-01 00:00:00
abstract::We report a case of splenic rupture after cesarean delivery for abruptio placentae. The diagnosis was not suspected until a laparotomy was performed. Diagnosis and management were complicated by disseminated intravascular coagulation and renal failure. The importance of early diagnosis and management modalities are di...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(95)90199-x
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the superior technique, if either, of the amniotic fluid index (AFI) vs the single deepest pocket technique in predicting an adverse pregnancy outcome among high-risk patients undergoing antenatal testing. STUDY DESIGN:Patients having modified biophysical profile (n...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ajog.2004.06.078
更新日期:2004-08-01 00:00:00
abstract::Healthy pregnant women underwent a mild exercise study to evaluate the effects of this amount of work on their fetuses. The results indicated that there were no direct correlations between exercise and fetal body or breathing movements at this particular work intensity (2.33 m). We found a relationship between the mat...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(83)90003-0
更新日期:1983-11-01 00:00:00
abstract::We report a case of placenta accreta that was managed conservatively by uterine arterial embolization and subsequently was complicated by hematuria. Ultrasound revealed a calcified mass at the posterior bladder wall. A careful resection under cystoscopy was carried out without hemorrhagic complication. Pathologic exam...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2009.08.040
更新日期:2009-11-01 00:00:00
abstract::With experience, and with the use of a 30-degree forward-oblique viewing telescope, sampling from one of the vessels of the umbilical cord produced at least 0.5 ml of pure fetal blood in 97% of the cases between 14 and 24 weeks' gestation; by aspiration through a short-tipped, 27-gauge, specially constructed needle, a...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(16)32794-6
更新日期:1980-12-15 00:00:00
abstract:OBJECTIVE:The aim of the study was to test the hypothesis that a combination of a previously devised morphologic scoring system and color flow-directed Doppler measurements would afford better discrimination between benign and malignant ovarian masses. STUDY DESIGN:The scoring system and color flow-directed Doppler me...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(12)90843-1
更新日期:1993-03-01 00:00:00
abstract::The natural history of genital herpes simplex virus (HSV) infections was investigated in 83 pregnancies in 78 women, and the information was used to determine the need for cesarean section in these women. We studied 163 recurrent episodes with HSV cultures from the cervix and from vulvar lesions every 1 to 3 days. Cer...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(83)90679-8
更新日期:1983-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the role of saline solution infusion sonohysterography in clinical practice in patients with abnormal uterine bleeding. STUDY DESIGN:A prospective case-controlled study was conducted comparing two-dimensional transvaginal imaging with saline solution infusion sonohys...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(97)70351-x
更新日期:1997-06-01 00:00:00
abstract::Women's health nurses and nurse practitioners have a unique opportunity to provide high-quality primary and preventive care and play a critical role in coordinating and delivering effective contraceptive methods. The strategies and techniques that they routinely employ during counseling and education can help improve ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.ajog.2011.07.001
更新日期:2011-10-01 00:00:00
abstract::Forty-five patients with histologically proved cervical dysplasia or carcinoma in situ were treated by the carbon dioxide-laser method. The carbon dioxide laser induces cell vaporization by causing intracellular steam combustion stimulated by the emission of a mixture of carbon dioxide, nitrogen, and helium. This meth...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(16)33126-x
更新日期:1978-08-15 00:00:00
abstract::Endometrial blood flow was measured through the menstrual cycle in nonpregnant women (28 studies of 17 women with normal menstrual cycles and 32 studies of 20 women with dysfunctional uterine bleeding) with use of a clearance technique in which 100 to 400 microCi of the gamma-emitting isotope, xenon 133 in saline solu...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(87)90229-8
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:Our purpose was to improve the accuracy of prenatal prognostication by directly correlating obstetric ultrasonographic measurements with neonatal survival. STUDY DESIGN:We studied 130 singleton live-born infants with birth weights between 500 and 1000 gm and who underwent complete ultrasonographic examinatio...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(93)90606-j
更新日期:1993-09-01 00:00:00
abstract::Primary cancers of the vagina are rare. They comprise 1% to 2% of all gynecologic malignancies and occur predominantly in older women. The diagnosis of primary carcinoma of the vagina requires that the cervix and vulva be intact and that no clinical evidence of other primary tumors exist. Approximately 90% of all vagi...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/s0002-9378(12)90738-3
更新日期:1991-10-01 00:00:00
abstract::This study was designed to re-evaluate neonatal condition at birth following elective cesarean section performed with epidural anesthesia and a modified technique of general anesthesia. Two groups of 20 patients were studied. Twenty received epidural anesthesia with 2 per cent lidocaine-carbon dioxide-epinephrine, and...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(79)90404-6
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to biomechanically characterize and compare human, porcine, equine, and ovine fetal membranes. STUDY DESIGN:Noncontact metrology was used for topographic analyses. Uniaxial tensile testing was performed to resolve specific biomechanical values. Puncture force and radial stresses...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2010.12.003
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to determine whether the frequency of fetal surveillance could be safely reduced from twice weekly to fortnightly in the case of small-for-gestational-age fetuses with normal results of umbilical artery Doppler velocimetry studies. STUDY DESIGN:Pregnant women between 24 and 36 weeks...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9378(00)70494-7
更新日期:2000-01-01 00:00:00
abstract::Neurofibromatosis adversely affects reproductive performance. Fetal growth retardation as a complication of pregnancy in patients with neurofibromatosis had not been widely documented. The present cases suggest that pregnant patients with neurofibromatosis may have an increased risk for growth-retarded babies. ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(87)80167-9
更新日期:1987-08-01 00:00:00
abstract::Ritodrine hydrochloride was administered parenterally to pregnant ewes during spontaneous or oxytocin-induced uterine activity. The effects of ritodrine on the uterus and cardiovasculature were assessed both with and without simultaneous administration of either alpha or beta blockade. Ritodrine was found to be an eff...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(76)90692-x
更新日期:1976-12-15 00:00:00
abstract:OBJECTIVE:Our purpose was to assess whether a program of expectant management of uncomplicated pregnancies in mothers with insulin-requiring gestational or pregestational class B reduces the incidence of cesarean birth. STUDY DESIGN:Two hundred women with uncomplicated, insulin-requiring diabetes at 38 weeks' gestatio...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9378(93)90631-r
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:We wished to determine third-year medical students' opinions and knowledge related to complementary and alternative medicine (CAM) in a school with no formal or elective course on the subject. STUDY DESIGN:A questionnaire was offered to third-year medical students during their 8-week rotation on obstetrics a...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2001.117484
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare different management strategies for women at risk for cervical incompetence. STUDY DESIGN:In an ongoing randomized trial patients with a previous preterm delivery at <34 weeks' gestation who met clinical criteria for the diagnosis of cervical incompetence are alloca...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mob.2000.108874
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the risk of cumulative cervical intraepithelial neoplasia (CIN) grade 2 or 3 according to initial colposcopy and directed biopsy results among women with low-grade squamous intraepithelial lesions (LSIL) or human papillomavirus (HPV) DNA positive atypical squamous ce...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2003.461
更新日期:2003-06-01 00:00:00
abstract::Although anovulation associated with hyperprolactinemia is not an uncommon cause of infertility, the precise mechanism of the pathogenic process that induces hyperactivity (hypertrophy with hyperplasia) of pituitary lactotropes is unknown. We have recently experienced a case of anovulation and hyperprolactinemia in a ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(87)80160-6
更新日期:1987-08-01 00:00:00
abstract::Follicular fluid samples were obtained by puncturing follicles of ovaries in situ from patients undergoing laparotomy. Sodium, potassium, chloride, magnesium, calcium, phosphorus, and sulfur concentrations measured by electron probe microanalysis were similar to those of blood, with minimal differences. This suggested...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(77)90690-1
更新日期:1977-05-15 00:00:00
abstract:OBJECTIVE:We sought to determine if genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway are associated with menopausal hot flashes via hormone levels. STUDY DESIGN:Women (n = 639) aged 45-54 years completed a study survey and provided blood for genetic and hormone analyses. The associations were a...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2012.05.019
更新日期:2012-09-01 00:00:00