Abstract：
OBJECTIVES:To report results on coverage, safety and logistics of a large-scale, school-based Vi polysaccharide immunization campaign in North Jakarta. METHODS:Of 443 primary schools in North Jakarta, Indonesia, 18 public schools were randomly selected for this study. Exclusion criteria were fever 37.5 degrees C or higher at the time of vaccination or a known history of hypersensitivity to any vaccine. Adverse events were monitored and recorded for 1 month after immunization. Because this was a pilot programme, resource use was tracked in detail. RESULTS:During the February 2004 vaccination campaign, 4828 students were immunized (91% of the target population); another 394 students (7%) were vaccinated during mop-up programmes. Informed consent was obtained for 98% of the target population. In all, 34 adverse events were reported, corresponding to seven events per 1000 doses injected; none was serious. The manufacturer recommended cold chain was maintained throughout the programme. CONCLUSIONS:This demonstration project in two sub-districts of North Jakarta shows that a large-scale, school-based typhoid fever Vi polysaccharide vaccination campaign is logistically feasible, safe and minimally disruptive to regular school activities, when used in the context of an existing successful immunization platform. The project had high parental acceptance. Nonetheless, policy-relevant questions still need to be answered before implementing a widespread Vi polysaccharide vaccine programme in Indonesia.
journal_name
Public Healthjournal_title
Public healthauthors
Agtini MD,Ochiai RL,Soeharno R,Lee HJ,Sundoro J,Hadinegoro SR,Han OP,Tana L,Halim FX,Ghani L,Delima,Lestari W,Sintawati FX,Kusumawardani N,Malik R,Santoso TS,Nadjib M,Soeroso S,Wangsasaputra F,Ali M,Ivanoff B,Gadoi
10.1016/j.puhe.2006.06.008subject
Has Abstractpub_date
2006-11-01 00:00:00pages
1081-7issue
11eissn
0033-3506issn
1476-5616pii
S0033-3506(06)00166-1journal_volume
120pub_type
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