Toxoplasmic chorioretinitis and antitumor necrosis factor treatment in rheumatoid arthritis.

Abstract:

OBJECTIVES:To present the data supporting the possible relationship of ocular toxoplasmosis to antitumor necrosis factor-alpha (TNF-alpha) therapy in patients with rheumatoid arthritis (RA). METHODS:A Medline search was performed using the words "toxoplasmosis, anti-TNF-alpha antagonists, chorioretinitis." We report 2 RA patients who developed ocular toxoplasmosis while receiving anti-TNF-alpha therapy. RESULTS:In addition to our patients with toxoplasmic chorioretinitis, there are 2 published cases of cerebral toxoplasmosis during treatment with anti-TNF-alpha agents. CONCLUSION:The risk of serious toxoplasmic infection during anti-TNF-alpha therapy for RA should be recognized.

journal_name

Semin Arthritis Rheum

authors

Lassoued S,Zabraniecki L,Marin F,Billey T

doi

10.1016/j.semarthrit.2006.08.004

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

262-3

issue

4

eissn

0049-0172

issn

1532-866X

pii

S0049-0172(06)00108-9

journal_volume

36

pub_type

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