Brain-behavior relationships in aphasia studied by positron emission tomography.

abstract：:Our previous studies have demonstrated that the methanol extract of heat-processed Panax ginseng C.A. Meyer exerts antioxidative, antiinflammatory, and anti-tumor-promoting effects. In the present study, we examined the antiinflammatory effects of several ginsenosides (Rb(1), Rc, Re, Rg(1), Rg(3)) derived from P. gins...

journal_title：Annals of the New York Academy of Sciences

authors： Surh YJ,Lee JY,Choi KJ,Ko SR

更新日期：2002-11-01 00:00:00

abstract：:Since the late sixties, several new antifungal drugs have become available. Initially, they were all intended for topical use, and, consequently, animal and human pharmacology always primarily aimed at confirming therapeutic efficacy. With the new tendency for the development of orally active antifungal drugs, human a...

journal_title：Annals of the New York Academy of Sciences

authors： Cauwenbergh G,Van Cutsem J

更新日期：1988-01-01 00:00:00

abstract：:Ticks do not usually infest sympatric hosts species according to their availability in a given environment, and it has been suggested that habitat use by hosts is a major determinant of tick burdens. The knowledge of such infestation patterns and their relationship with host habitat use is important for the control of...

journal_title：Annals of the New York Academy of Sciences

authors： De Garine-Wichatitsky M

更新日期：2002-10-01 00:00:00

abstract：:In the study reported in this paper, we characterized PACAP in the human fetal adrenal gland and we investigated the effect of PACAP on steroid secretion from cultured fetal adrenal cells. The adrenal gland from 20-week-old fetuses contained substantial concentrations of PACAP-immunoreactive material (88.6 ng/g wet ti...

journal_title：Annals of the New York Academy of Sciences

authors： Breault L,Yon L,Montéro M,Chouinard L,Contesse V,Delarue C,Fournier A,Lehoux JG,Vaudry H,Gallo-Payet N

更新日期：2000-01-01 00:00:00

abstract：:Zoonoses are animal and human diseases. Q fever is primarily a zoonosis-an animal disease that can be transmitted to humans under certain conditions. Recent epidemiological studies suggest that Q fever should be considered as a public health problem in many countries where it is present, but unrecognizable due to inad...

journal_title：Annals of the New York Academy of Sciences

authors： Beslagić E,Hamzić S,Beslagić O,Zvizdić S

更新日期：2006-10-01 00:00:00

abstract：:Anatomic and electrophysiologic studies have provided evidence that CRF meets some of the criteria as a neurotransmitter in the noradrenergic nucleus, the locus coeruleus (LC), although some of the criteria have yet to be satisfied. Thus, immunohistochemical findings suggest that CRF innervates the LC, but this must b...

journal_title：Annals of the New York Academy of Sciences

authors： Valentino RJ,Foote SL,Page ME

更新日期：1993-10-29 00:00:00

abstract：:Aging may pose a challenge to the central nervous system, increasing its susceptibility to apoptotic events. Recent findings indicate that caloric restriction (CR) may have a profound effect on brain function and vulnerability to injury and diseases, by enhancing neuroprotection, stimulating the production of new neur...

journal_title：Annals of the New York Academy of Sciences

authors： Hiona A,Leeuwenburgh C

更新日期：2004-06-01 00:00:00

abstract：:Developmental robustness, the capacity to stay "on track" despite the myriad vicissitudes that inevitably plague a developing organism, is, I argue, a prerequisite for natural selection and key to our understanding of the evolution of developmental processes. But how is such robustness achieved? And how can we reconci...

journal_title：Annals of the New York Academy of Sciences

authors： Keller EF

更新日期：2002-12-01 00:00:00

abstract：:Cancer chemoprevention entails the ingestion of dietary or pharmaceutical agents that can prevent, delay, or reverse the process of carcinogenesis. With support provided by the National Cancer Institute, we have been actively engaged in the systematic discovery and characterization of natural chemopreventive agents. T...

journal_title：Annals of the New York Academy of Sciences

authors： Pezzuto JM

更新日期：2011-01-01 00:00:00

abstract：:The strategy of antigenic variation is to present a constantly changing population phenotype that enhances parasite transmission, through evasion of immunity arising within, or existing between, host animals. Trypanosome antigenic variation occurs through spontaneous switching among members of a silent archive of many...

journal_title：Annals of the New York Academy of Sciences

authors： Barry JD,Hall JP,Plenderleith L

更新日期：2012-09-01 00:00:00

abstract：:The Mediterranean diet is now recognized as being both limited in toxicity and abundant in nutrient and non-nutrient protective factors. A large body of basic, clinical and epidemiological studies have been developed in recent years to provide evidence of the benefits of the Mediterranean diet or its components on hea...

journal_title：Annals of the New York Academy of Sciences

authors： Covas MI,Marrugat J,Fitó M,Elosua R,de la Torre-Boronat C

更新日期：2002-05-01 00:00:00

abstract：:Babesia felis, originally identified in wild cats in the Sudan, was subsequently found to cause clinical disease in domestic cats. Although babesiosis in domestic cats has been reported sporadically from various countries, as a significant disease it appears to be a distinctly South African phenomenon. Apart from an i...

journal_title：Annals of the New York Academy of Sciences

authors： Penzhorn BL,Schoeman T,Jacobson LS

更新日期：2004-10-01 00:00:00

abstract：:Platelets play important roles for hemostasis with activated platelets adhering to the injured vessel wall to initiate platelet aggregation. At the same time, our study revealed the cytotoxic effect on endothelial cells characterized by an increase of intracellular Ca++ and a decrease of EDRF production, which may cau...

journal_title：Annals of the New York Academy of Sciences

authors： Numano F,Kishi Y,Ashikaga T,Hata A,Makita T,Watanabe R

更新日期：1995-01-17 00:00:00

abstract：:The effect of carcinogenesis on various hepatic microsomal parameters and related cell functions was studied in two tumor models. Hepatocarcinoma was produced by diethylnitrosamine (DEN) and 2-acetylaminofluorene (2-AAF) (Solt-Farber model) and mammary adenocarcinoma using R3230 AC cancer cell line. In these models th...

journal_title：Annals of the New York Academy of Sciences

authors： Feuer G

更新日期：1988-01-01 00:00:00

abstract：:Estrogens are represented by a diverse group of compounds. Within this large family of molecules are tissue-selective estrogens that have been classified as selective estrogen receptor modulators (SERMs). These compounds are characterized by the fact that they exhibit both estrogen agonist and antagonist activity depe...

journal_title：Annals of the New York Academy of Sciences

authors： Komm BS,Lyttle CR

更新日期：2001-12-01 00:00:00

abstract：:The class of adhesion G protein-coupled receptors (aGPCRs), with 33 human homologs, is the second largest family of GPCRs. In addition to a seven-transmembrane α-helix-a structural feature of all GPCRs-the class of aGPCRs is characterized by the presence of a large N-terminal extracellular region. In addition, all aGP...

journal_title：Annals of the New York Academy of Sciences

authors： Liebscher I,Ackley B,Araç D,Ariestanti DM,Aust G,Bae BI,Bista BR,Bridges JP,Duman JG,Engel FB,Giera S,Goffinet AM,Hall RA,Hamann J,Hartmann N,Lin HH,Liu M,Luo R,Mogha A,Monk KR,Peeters MC,Prömel S,Ressl S,Sc

更新日期：2014-12-01 00:00:00

abstract：:Continuous dopamine (DA) stimulation is a therapeutic approach that applies to the treatment of motor fluctuations due to pulsatile DA stimulation in Parkinson's disease (PD), to cure the abuse of drugs, such as cocaine or amphetamine (which produce short-lasting peaks of extracellular DA), and as a safe therapeutic a...

journal_title：Annals of the New York Academy of Sciences

authors： Biagioni F,Busceti CL,Molinaro G,Battaglia G,Giorgi FS,Ruggieri S,Fornai F

更新日期：2006-08-01 00:00:00

abstract：:Phosphorus nuclear magnetic resonance studies of various normal and dystrophic muscles have demonstrated differences in phosphodiester contents. Dystrophic chicken pectoralis muscle contains elevated levels of the diester SEP, and Duchenne dystrophic human leg muscle lacks the diester GPC. It is shown that SEP may be ...

journal_title：Annals of the New York Academy of Sciences

authors： Chalovich JM,Burt CT,Danon MJ,Glonek T,Bárány M

更新日期：1979-01-01 00:00:00

abstract：:Bone marrow transplantation (BMT) is currently a procedure that is associated with high morbidity and mortality. Thus, the clinical application of this technique is limited to the treatment of life-threatening hematopoietic malignancies. The morbidity and mortality of BMT is mainly related to graft-versus-host disease...

journal_title：Annals of the New York Academy of Sciences

authors： Exner BG,Domenick MA,Bergheim M,Mueller YM,Ildstad ST

更新日期：1999-04-30 00:00:00

abstract：:We found a novel genetic abnormality, heterozygous C-->T nucleotide substitution at position -1138 bp in the 5'-flanking region of the fibrinogen A alpha gene, in patients with hypofibrinogenemia. Luciferase reporter assay using the pGL3-basic vector and CHO cells indicates that the transcriptional activity of a vecto...

journal_title：Annals of the New York Academy of Sciences

authors： Okumura N,Terasawa F,Yonekawa O,Hamada E,Kaneko H

更新日期：2001-01-01 00:00:00

abstract：:We have presented evidence indicating that P2-purinergic receptors may activate the polyphosphoinositide-phospholipase C in HL60 cells via the mediation of a pertussis-toxin-sensitive GTP-binding protein, which also mediates the actions of chemotactic peptide receptors in these and other phagocytic white blood cells. ...

journal_title：Annals of the New York Academy of Sciences

authors： Dubyak GR,Cowen DS,Lazarus HM

更新日期：1988-01-01 00:00:00

abstract：:The aim of this study was to examine changes in muscle cell injury and antioxidant capacity of weightlifters following a 1-week intensive resistance-training regimen. Thirty-six female subjects participated in this study, and their ages ranged from 18 to 25 years. The sample group included 19 elite weightlifters with ...

journal_title：Annals of the New York Academy of Sciences

authors： Liu JF,Chang WY,Chan KH,Tsai WY,Lin CL,Hsu MC

更新日期：2005-05-01 00:00:00

abstract：:The molecular genetic basis of adaptive change in phenotype is a major outstanding issue in evolutionary biology. Evolutionary change in coat and plumage color is a promising system for making progress in this field. Most notably, recent work on the molecular genetic basis of hair and feather color has identified seve...

journal_title：Annals of the New York Academy of Sciences

authors： Mundy NI,Kelly J,Theron E,Hawkins K

更新日期：2003-06-01 00:00:00

abstract：:The investigation of immune senescence has uncovered many changes in B cell development, maintenance, and function with increasing age. However, most of these studies have focused on conventional B cell subsets in the spleen. The B-1 cell subset is an essential arm of the innate immune system, which in general has bee...

journal_title：Annals of the New York Academy of Sciences

authors： Holodick NE,Rothstein TL

更新日期：2015-12-01 00:00:00

abstract：:We have established several tumor T cell lines, both from the skin and from the blood of a patient with an MHC class II-/class I+, CD4+ cutaneous T cell lymphoma (CTCL). These cell lines, like the initial tumor cells, had a CD3+CD4+CD8- phenotype. We also isolated two cytotoxic T lymphocyte clones from the tumor site ...

journal_title：Annals of the New York Academy of Sciences

authors： Bagot M,Nikolova M,Schirm-Chabanette F,Wechsler J,Boumsell L,Bensussan A

更新日期：2001-09-01 00:00:00

abstract：:Alterations in the gain of the vertical angular vestibulo-ocular reflex (VOR) are dependent on the head position in which the gain changes were produced. We determined how long gravity-dependent gain changes last in monkeys after four hours of adaptation, and whether the adaptation is mediated through the nodulus and ...

journal_title：Annals of the New York Academy of Sciences

authors： Yakushin SB,Bukharina SE,Raphan T,Buttner-Ennever J,Cohen B

更新日期：2003-10-01 00:00:00

abstract：:Chemical hypoxia produces depletion of ATP, intracellular Ca2+ overload, and cell death. The role of Na+/Ca2+ exchanger (NCX), the major plasma membrane Ca2+ extruding system, has been explored in chemical hypoxia using BHK cells stably transfected with the three mammalian NCX isoforms: NCX1, NCX2, and NCX3. Here we r...

journal_title：Annals of the New York Academy of Sciences

authors： Secondo A,Staiano IR,Scorziello A,Sirabella R,Boscia F,Adornetto A,Canzoniero LM,Di Renzo G,Annunziato L

更新日期：2007-03-01 00:00:00

abstract：:We examined the effects of a nonantimicrobial tetracycline analogue, CMT-8, on bone loss and osteoclasts in ovariectomized (OVX) rats. Three-month-old female rats were OVX, and, one week later, distributed into three groups: sham-operated non-OVX controls, untreated OVX controls, and CMT-8-treated OVX rats. After 145 ...

journal_title：Annals of the New York Academy of Sciences

authors： Sasaki T,Ohyori N,Debari K,Ramamurthy NS,Golub LM

更新日期：1999-06-30 00:00:00

abstract：:N. gonorrhoeae initiates infection by adhering to and invading columnar epithelial cells. Over time these activities often induce inflammation, with the influx of neutrophils and serum into the urethral lumen, cervical os, conjunctiva, and the like. At least some of these infected niches contain CMP-NANA (cytidine mon...

journal_title：Annals of the New York Academy of Sciences

authors： Rest RF,Liu J,Talukdar R,Frangipane JV,Simon D

更新日期：1994-08-15 00:00:00

abstract：:Adult (3-month-old) and aged (28-month-old) rats that had been pretreated with 5,7-DHT in both lateral ventricles received grafts of cell suspensions taken from the RR or MR regions taken from the embryonic stages E12-21. These cell suspensions were implanted unilaterally into the rostral part of the hippocampus or th...

journal_title：Annals of the New York Academy of Sciences

authors： Steinbusch HW,Beek A,Frankhuyzen AL,Tonnaer JA,Gage FH,Björklund A

更新日期：1987-01-01 00:00:00