当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Risk factors for wound healing complications in sirolimus-treated renal transplant recipients.

Risk factors for wound healing complications in sirolimus-treated renal transplant recipients.

Abstract：

:Impaired surgical site healing occurs in 20% to 50% of sirolimus (SRL)-treated renal transplant (RT) recipients, with most patients having received concomitant corticosteroids. We determined the incidence of surgical site complications among RT recipients receiving SRL with mycophenolate mofetil (MMF), with most patients on a steroid-avoidance protocol. SRL/MMF patients with complications within 3 months of transplantation were compared with 1) SRL/MMF patients without them and 2) matched RT recipients receiving tacrolimus (FK)/MMF. Between January 2002 and March 2005, 44 of 300 (15%) RT recipients received SRL within 6 weeks of transplantation. Fourteen (31.8%) developed lymphocele, bladder leak, wound dehiscence, cellulitis, or an abscess. Obesity (BMI > or =30 kg/m2) was significantly associated with problems: the mean BMI of SRL cases with complications was 29.9 kg/m2 vs 25.4 kg/m2 for SRL patients without them (P = .047). Seventy-one percent of obese SRL patients experienced complications compared with 24.3% (P = .025) of non-obese SRL patients. Surgical treatment was required in 29% of patients. Rates of maintenance steroid use were similar in SRL complicated cases compared with SRL patients without them. The FK control group showed a lower rate of complications (14.3%; P = .163) despite similar BMI, rejection rates, and chronic steroid use as the SRL group. Obesity and graft rejection were independent predictors of complications. Thus, among a group of predominantly steroid-free recipients on SRL, the rates of wound complications were similar to those seen previously, but the highest risk for them was observed in obese recipients and in those with acute rejection episodes. Wound complications were associated with significant morbidity.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Grim SA,Slover CM,Sankary H,Oberholzer J,Benedetti E,Clark NM

doi

10.1016/j.transproceed.2006.10.065

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

3520-3

issue

10

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(06)01294-2

journal_volume

38

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Biopsies in renal transplant patients with proteinuria: histological findings.

    abstract：INTRODUCTION:Proteinuria is related to a poor prognosis for graft survival. MATERIALS AND METHODS:We undertook a retrospective study of renal transplant biopsies between 2006 and 2009 performed because of proteinuria. Data were collected on demographic, analytical, and histological characteristics. RESULTS:The study ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.05.027

    authors： López V,Sola E,Jironda C,León M,García I,Gutierrez C,Cabello M,Burgos D,González-Molina M,Hernandez D

    更新日期：2011-07-01 00:00:00

  • Use of elderly living kidney donors: twenty years' experience in the Balkans.

    abstract：:The Balkan region has dramatically changed during the last 20 years. Despite transplantation efforts, dialysis remains the usual way to treat end stage renal diseases. Living donor renal transplantation is still the predominant transplant activity. Seeking to solve the problem, we decided to accept expanded criteria l...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.09.026

    authors： Ivanovski N,Masin J,Kolevski P,Stojceva-Taneva O,Popov Z

    更新日期：2011-11-01 00:00:00

  • Monitoring of intrasplenic hepatocyte transplantation for acute-on-chronic liver failure: a prospective five-year follow-up study.

    abstract：BACKGROUND:Acute-on-chronic liver failure (ACLF) is defined as an acute deterioration of chronic liver disease. Intrasplenic hepatocyte transplantation is increasingly recognized as a treatment for liver failure and genetic metabolic liver diseases. We describe our experience of intrasplenic hepatocyte transplantation ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.10.042

    authors： Wang F,Zhou L,Ma X,Ma W,Wang C,Lu Y,Chen Y,An L,An W,Yang Y

    更新日期：2014-01-01 00:00:00

  • Risk Factors of Prolonged ICU Stay in Liver Transplant Recipients in a Single-Center Experience.

    abstract：BACKGROUND:Prolonged initial intensive care unit (ICU) stay after liver transplantation (LT) is associated with prolonged total hospitalization, increased hospital mortality, and impaired patient and graft survival. Recent data suggested that model for end-stage liver disease (MELD) score at the time of LT and the leng...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.02.143

    authors： Niewińsk G,Raszeja-Wyszomirska J,Główczyńska R,Figiel W,Zając K,Kornasiewicz O,Zieniewicz K,Grąt M

    更新日期：2018-09-01 00:00:00

  • Prognostic evaluation of the donor risk index among a prospective cohort of Italian patients undergoing liver transplantation.

    abstract：BACKGROUND/AIM:The definition of an extended criteria donor for orthotopic liver transplantation (OLT) remains controversial. The donor risk index (DRI) has become the main tool to define the marginality of hepatic grafts in the United States. The aim of this study was to prospectively evaluate the prognostic ability o...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.03.097

    authors： Vitale A,D'Amico F,Gringeri E,Valmasoni M,Pauletto A,Bonsignore P,Bassi D,D'Amico FE,Polacco M,Burra P,Russo F,Angeli P,Poci C,Feltracco P,Romano A,Cillo U

    更新日期：2009-05-01 00:00:00

  • Delayed Recovery of Renal Function After Donor Nephrectomy.

    abstract：BACKGROUND:Many living kidney donors are still at risk of chronic kidney disease (CKD) 1 year after nephrectomy. Although some donors still experience poor renal function, many exhibit delayed recovery of renal function afterwards. We studied the factors related to delayed recovery of renal function in patients with CK...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.01.038

    authors： Na JC,Park JS,Yoon MG,Lee HH,Yoon YE,Huh KH,Kim YS,Han WK

    更新日期：2018-05-01 00:00:00

  • Resistant Cytomegalovirus Infection in Solid-organ Transplantation: Single-center Experience, Literature Review of Risk Factors, and Proposed Preventive Strategies.

    abstract：BACKGROUND:Cytomegalovirus (CMV) infection causes morbidity and mortality in solid-organ transplant recipients. Drug-resistant CMV is an emerging problem with poor survival outcomes and limited therapeutic options. In this study we comprehensively address the issue of drug resistance in CMV when compared with standard ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,评审

    doi：10.1016/j.transproceed.2018.02.091

    authors： Majeed A,Latif A,Kapoor V,Sohail A,Florita C,Georgescu A,Zangeneh T

    更新日期：2018-12-01 00:00:00

  • Rescue of Discarded Grafts for Liver Transplantation by Ex Vivo Subnormothermic and Normothermic Oxygenated Machine Perfusion: First Experience in Spain.

    abstract：BACKGROUND:Ex vivo machine perfusion (MP) has been reported as a possibly method to rescue discarded organs. The main aim of this study was to report an initial experience in Spain using MP for the rescue of severely marginal discarded liver grafts, and to, secondarily, define markers of viability to test the potential...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.04.092

    authors： Ciria R,Ayllon-Teran MD,González-Rubio S,Gómez-Luque I,Ferrín G,Moreno A,Sánchez-Frías M,Alconchel F,Herrera C,Martín V,Sánchez-Hidalgo JM,Arjona-Sánchez Á,Okuda Y,Cabrera I,Benavente B,Rodriguez MJ,Jurado-Martínez I,Du

    更新日期：2019-01-01 00:00:00

  • Liver Transplant Recipients With End-Stage Renal Disease Largely Benefit From Kidney Transplantation.

    abstract：BACKGROUND:The incidence of end-stage renal disease (ESRD) after liver transplant (LT) has increased. The actual benefit of kidney transplantation (KT) is not completely understood in LT recipients with ESRD. METHODS:We analyzed Scientific Registry of Transplant Recipients data for all KT candidates with prior LT from...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2017.11.009

    authors： Yunhua T,Qiang Z,Lipeng J,Shanzhou H,Zebin Z,Fei J,Zhiheng Z,Linhe W,Weiqiang J,Dongping W,Zhiyong G,Xiaoshun H

    更新日期：2018-01-01 00:00:00

  • Development of Squamous Cell Carcinoma After Pulmonary Aspergillosis in the Native Lung of a Lung Transplant Recipient: A Case Report.

    abstract：:Lung transplant recipients have a significant incidence of posttransplant lung nodules. Such nodules can occur from various etiologies, both in the lung allograft or in the native lung. They most commonly originate from infections, such as Pseudomonas or Aspergillus species, or from posttransplant lymphoproliferative ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.07.034

    authors： Madan N,Abdelrazek H,Patil PD,Ross MD,Roy SB,Thawani N,Hahn MF,Bremner RM,Panchabhai TS

    更新日期：2018-12-01 00:00:00

  • Prograf five milligrams versus Tacrolimus medis in healthy volunteers: a bioequivalence study.

    abstract：:For FDA approval, bioequivalence of a generic version of Tacrolimus must be demonstrated in a randomized, two-treatments, two-periods, two-sequences, single-dose crossover study in healthy adult volunteers. Currently there are at least 3 differents generic equivalent for Tacrolimus, that are approved by the EMA and th...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.transproceed.2013.08.104

    authors： Masri M,Rizk S,Boujbel L,Bellahirich W,Baassoumi D,Attia M,Matha V

    更新日期：2013-01-01 00:00:00

  • Laparoscopic treatment of biliary peritonitis after removal of T-tube in liver transplant patients.

    abstract：INTRODUCTION:T-tube removal in liver transplant patients can occasionally cause a massive biliary leak and may require surgical treatment for its resolution. We present our experience with a laparoscopic approach to biliary peritonitis in liver transplant patients after the removal of a T-tube. PATIENTS AND METHODS:Fr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.05.018

    authors： Cascales Campos P,Ramírez Romero P,González R,Pons JA,Miras M,Sanchez Bueno F,Robles R,Parrilla P

    更新日期：2012-07-01 00:00:00

  • Outcomes of expanded-criteria deceased donor kidney transplantation in a single center.

    abstract：BACKGROUND:In an effort to expand the deceased donor pool, transplant centers have accepted expanded-criteria donors as appropriate for many of the patients in the deceased donor pool. We investigated expanded-criteria deceased donor kidney transplantation and compared the outcomes of kidney transplantation according t...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.12.014

    authors： Kim BS,Joo SH,Ahn HJ,Choi JH,Lee SH,Park HC

    更新日期：2014-05-01 00:00:00

  • Neonatal pig pancreatic duct-derived insulin-producing cells: preliminary in vitro studies.

    abstract：:Neonatal pig pancreata could represent an ideal tissue resource for donor islets for transplantation trials. Because functional islet beta-cells could derive from precursors situated in the ductal system, and neonatal animals are better suitable than adults for recovering such elements, we have examined whether isolat...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.03.074

    authors： Basta G,Racanicchi L,Mancuso F,Guido L,Macchiarulo G,Luca G,Calabrese G,Brunetti P,Calafiore R

    更新日期：2004-04-01 00:00:00

  • Effect of early recurrence of hepatitis C on late biliary anastomotic stricture after liver transplantation.

    abstract：:The aim of the current study was to clarify whether recurrence of hepatitis C (HCV) infection affects biliary complications after liver transplantation (OLT), with special reference to late biliary anastomotic strictures (LBAS). We reviewed 665 consecutive adult OLT recipients with a choledochocholedochostomy without ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.10.131

    authors： Fujikawa T,Fujita S,Mekeel KL,Reed AI,Foley DP,Kim RD,Howard RJ,Hemming AW

    更新日期：2006-12-01 00:00:00

  • Heat inactivation can differentiate between IgG and IgM antibodies in the pretransplant cross match.

    abstract：:The presence of IgG antibodies in the pretransplant cross-match (XM) test results in hyperacute rejection, but IgM antibodies are inconsequential. The XM should be able to differentiate between IgG and IgM antibodies. This study evaluated 3 methods. This study was based on 500 patients for whom XM were performed betwe...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.07.045

    authors： Al-Muzairai IA,Mansour M,Almajed L,Alkanderi N,Alshatti N,Samhan M

    更新日期：2008-09-01 00:00:00

  • Donor risk index does not predict graft survival after pancreas transplantation in Brazil.

    abstract：BACKGROUND:Pancreas donor risk index (DRI) was developed by using large multicenter American data to predict the risk of adverse outcomes in pancreas transplantation based on donor and technical/logistical characteristics. AIM:The goal of this study was to evaluate the usefulness of the DRI in predicting graft surviva...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.03.034

    authors： Amaral PH,Genzini T,Perosa M,Massarollo PC

    更新日期：2015-05-01 00:00:00

  • Examination of the role of the colloids hydroxyethylstarch, dextran, human albumin, and plasma proteins in a modified UW solution.

    abstract：:The delayed contralateral nephrectomy procedure (three-step) produced inconsistent results, indicating that the preserved autotransplanted kidney tends to remain unfunctional and to regenerate incompletely unless the demand for work is placed upon it. Omission of HES in UW (UW-plain) did not affect preservation succes...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：

    authors： Schlumpf R,Morel P,Loveras JJ,Condie RM,Matas A,Kurle J,Najarian JS,Sutherland DE

    更新日期：1991-10-01 00:00:00

  • Development of the National Kidney Transplantation Program in Uruguay.

    abstract：:The first kidney transplantation (KT) in Uruguay was performed in 1969. We report the rates of KT and survival of patients and grafts up to December 2014. The country has a surface of 176,215 km(2) and a population of 3,286,314 inhabitants (18.6 inhabitants per km(2)). Till December 31, 2014, 1,940 KT have been perfor...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.09.001

    authors： González-Martínez F,Orihuela S,Alvarez I,Dibello N,Curi L,Nin M,Wimber E,Mizraji R,Bengochea M,González G,Manzo L,Toledo R,Silva W,Chopitea Á,Lopez D,Balboa O,Porto D,Noboa O

    更新日期：2015-10-01 00:00:00

  • Complex Congenital Heart Disease: Is Heart Transplantation an Option?

    abstract：INTRODUCTION:Within the heart transplant (HT) population, few patients have complex congenital heart disease (CHD) underlying disease. Our objective is to assess the complications and follow-up of patients with CHD transplanted in our center (1991-present). MATERIAL AND METHODS:Retrospective analysis of patients older...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2017.09.060

    authors： Esteve-Ruiz I,Grande-Trillo A,Rangel-Sousa D,Adsuar-Gómez A,Sobrino-Márquez M,Lage-Gallé E

    更新日期：2018-03-01 00:00:00

  • Experience with cyclosporine: from revolution to evolution of immunosuppressive protocols in thoracic organ transplantation.

    abstract：:The introduction of cyclosporine into clinical practice of thoracic organ transplantation had a dramatic and positive effect on both short- and long-term survival. Today, the majority of patients are still treated with this drug, and different immunosuppressive combination therapies have further resulted in improved l...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.01.048

    authors： Haverich A,Gorler H

    更新日期：2004-03-01 00:00:00

  • Real-time monitoring of nitric oxide (NO) and pO2 levels under ischemic conditions associated with small bowel ischemia/reperfusion injury using selective electrodes for NO and oxygen molecules.

    abstract：:The present study demonstrated the feasibility of monitoring nitric oxide (NO) and pO2 levels under ischemic conditions associated with small bowel ischemia/reperfusion (I/R) injury through the use of selective electrodes for NO and oxygen molecules. NO levels gradually increased during ischemia. When reperfusion was ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.08.090

    authors： Watanabe T,Owada S,Kobayashi H,Ishiuchi A,Nakano H,Asakuta T,Shimamura T,Asano T,Koizumi S,Jinnouchi Y,Katayama M,Kamibayasi M,Murakami E,Otsubo T

    更新日期：2007-12-01 00:00:00

  • Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place.

    abstract：UNLABELLED:Organ rejection and inflammation are accompanied by endothelial cell activation. An in vitro model with patient-specific endothelial cells was used to study the impact of mTOR inhibitors on cell growth and release of proinflammatory cytokines. MATERIAL AND METHODS:Confluent monolayers of human saphenous vei...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.12.140

    authors： Lehle K,Birnbaum DE,Preuner JG

    更新日期：2005-01-01 00:00:00

  • Age, gender, race, and associations with kidney failure following living kidney donation.

    abstract：INTRODUCTION:Our previous reports suggested that African Americans (AA) are more likely to develop end-stage renal disease (ESRD) following kidney donation when compared with white counterparts. We sought information on age, gender, and race of kidney donors to determine which groups were over-represented on the kidney...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.03.104

    authors： Gibney EM,Parikh CR,Garg AX

    更新日期：2008-06-01 00:00:00

  • Color Doppler findings in transplanted kidneys and remnant kidneys of donors 6 to 12 months after kidney transplantation.

    abstract：OBJECTIVES:Ultrasonography and color Doppler have been used extensively in the evaluation of transplanted kidney. The aim of this study was evaluation and comparison of color Doppler sonography findings in the remnant kidney of living donors and the transplanted kidney at 6 to 12 months after kidney transplantation. M...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.04.015

    authors： Khosroshahi HT,Tarzamni MK,Gojazadeh M,Bahluli A

    更新日期：2007-05-01 00:00:00

  • The minimal flush volume for washout of preservation fluid in liver transplantation.

    abstract：OBJECTIVES:Organ preservation is one of the important steps that predicts the patient outcome. However, after revascularization, the high concentration of potassium that influxes into the circulation might cause immediate postreperfusion hyperkalemia. To prevent this complication, the portal vein has been washed out wi...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.06.035

    authors： Homvises B,Sirivatanauksorn Y,Limsrichamrern S,Pongraweewan O,Sujirattanawimol K,Raksakietisak M

    更新日期：2008-09-01 00:00:00

  • Prolongation of islet allograft survival by coexpression of CTLA4Ig and CD40LIg in mice.

    abstract：BACKGROUND:B7/CD28 and CD40/CD40L have been well established as important costimulatory pathways. Cytotoxic T lymphocyte-associated antigen-4 (CTLA4) delivers negative signals to antigen-presenting cells to down-regulate proinflammatory responses and competitively inhibits the binding of B7 and CD28. Signals from the C...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.09.025

    authors： Li ZL,Xue WJ,Tian PX,Ding XM,Tian XH,Feng XS,Hou J

    更新日期：2007-12-01 00:00:00

  • Granzyme B and perforin as predictive markers for acute rejection in human intestinal transplantation.

    abstract：:In human heart and kidney transplantations, granzyme B (GrB) and perforin have both been shown to be predictive markers for acute cellular rejection (ACR). We investigated the tissue expression and possible relationship of GrB and perforin to the clinical outcome, histopathology, and function of intestinal transplants...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2003.10.073

    authors： D'Errico A,Corti B,Pinna AD,Altimari A,Gruppioni E,Gabusi E,Fiorentino M,Bagni A,Grigioni WF

    更新日期：2003-12-01 00:00:00

  • Anxiety, depression and emotional profile in renal transplant recipients and healthy subjects: a comparative study.

    abstract：BACKGROUND:Renal transplantation is a well established treatment for end-stage renal disease. However, recipients have been shown to develop emotional distress and affective disorders, such as anxiety and depression, associated with a compromised quality of life. Some accounts report an improvement of affective disorde...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.08.056

    authors： Pascazio L,Nardone IB,Clarici A,Enzmann G,Grignetti M,Panzetta GO,Vecchiet C

    更新日期：2010-11-01 00:00:00

  • Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Failure in a Liver Transplant Patient: A Case Report.

    abstract：:Intraoperative extracorporeal membrane oxygenation (ECMO) support, both venoarterial and venovenous (VV), have been used sparingly and with limited success in the setting of liver transplantation. Here, we report the successful use of VV-ECMO in the resuscitation and pulmonary bridging support after severe systemic in...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.07.013

    authors： Kim IK,Nissen NN,Steggerda J,Gereboff A,Sharma V,Kariger R,Klein AS,Annamalai A,Todo T,Nurok M,Dong E,Friedman O,Jordan SC,Ramzy D

    更新日期：2018-12-01 00:00:00