Abstract:
:In this study we investigated the potential impact of climate change in Portugal on heat-related mortality, air pollution-related health effects, and selected vectorborne diseases. The assessment used climate scenarios from two regional climate models for a range of future time periods. The annual heat-related death rates in Lisbon may increase from between 5.4 and 6 per 100,000 in 1980-1998 to between 8.5 and 12.1 by the 2020s and to a maximum of 29.5 by the 2050s, if no adaptations occur. The projected warmer and more variable weather may result in better dispersion of nitrogen dioxide levels in winter, whereas the higher temperatures may reduce air quality during the warmer months by increasing tropospheric ozone levels. We estimated the future risk of zoonoses using ecologic scenarios to describe future changes in vectors and parasites. Malaria and schistosomiasis, which are currently not endemic in Portugal, are more sensitive to the introduction of infected vectors than to temperature changes. Higher temperatures may increase the transmission risk of zoonoses that are currently endemic to Portugal, such as leishmaniasis, Lyme disease, and Mediterranean spotted fever.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Casimiro E,Calheiros J,Santos FD,Kovats Sdoi
10.1289/ehp.8431subject
Has Abstractpub_date
2006-12-01 00:00:00pages
1950-6issue
12eissn
0091-6765issn
1552-9924journal_volume
114pub_type
杂志文章abstract:BACKGROUND:Air pollution data in Bangkok, Thailand, indicate that levels of particulate matter with aerodynamic diameter < or = 10 microm (PM(10)) are significantly higher than in most cities in North America and Western Europe, where the health effects of PM(10) are well documented. However, the pollution mix, seasona...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.10849
更新日期:2008-09-01 00:00:00
abstract::Scaling of the quantified dispositional parameters of xenobiotics from animals to man is of interest from the standpoint of toxicology (e.g., poisoning and risk assessment). Scaling is also important from the standpoint of therapeutics because it represents a strategy for predicting first-use-in-human doses in clinica...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.96104400
更新日期:1996-04-01 00:00:00
abstract::In 1976, near Seveso, Italy, an industrial accident caused the release of large quantities of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) into the atmosphere, resulting in the highest levels of the toxicant ever recorded in humans. The contaminated area was divided into three zones (A, B, R) corresponding to decreasing...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.98106273
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Pterygium is a fibrovascular growth of the bulbar conjunctiva and underlying subconjunctival tissue that may cause blindness. The mechanism of pterygium formation is not yet fully understood, but pterygium has some tumorlike features. OBJECTIVES:The objective of this study was to evaluate the association be...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.11111
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Because of complex interactions of climate variables at the levels of the pathogen, vector, and host, the potential influence of climate change on vector-borne and zoonotic diseases (VBZDs) is poorly understood and difficult to predict. Climate effects on the nonvector-borne zoonotic diseases are especially ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.0901389
更新日期:2010-11-01 00:00:00
abstract::A major goal of studying farmworkers is to better understand how their work environment, including exposure to pesticides, affects their health. Although a number of health conditions have been associated with pesticide exposure, clear linkages have yet to be made between exposure and health effects except in cases of...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.8526
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:The National Environmental Policy Act and related state laws require many public agencies to analyze and disclose potentially significant environmental effects of agency actions, including effects on human health. In this paper we review the purpose and procedures of environmental impact assessment (EIA), ex...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.11132
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Despite experimental evidence, most epidemiologic studies to date have not supported an association between exposure to persistent organic pollutants (POP) and breast cancer incidence in humans. This may be attributable to difficulties in estimating blood/tissue POP concentration at critical time periods of ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.10917
更新日期:2008-07-01 00:00:00
abstract::[This corrects the article DOI: https://doi.org/10.1289/EHP507.]. ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,已发布勘误
doi:10.1289/EHP3422
更新日期:2018-02-20 00:00:00
abstract::Africa is quickly becoming a destination for information technology in the form of tons of used computers, fax machines, cell phones, and other electronics. Although many of these machines can be repaired and resold, up to 75% of the electronics shipped to Africa is junk. This equipment, when dumped, may leach lead, m...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.114-a232
更新日期:2006-04-01 00:00:00
abstract::With the "graying of America," the prevalence of neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease (PD) will make increasingly greater demands on Medicare/Medicaid resources, which will greatly strain the national economy. It is imperative that prevention and intervention strategies for t...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::Methylation is considered the detoxification pathway for inorganic arsenic (InAs), an established human carcinogen. Urinary speciation analysis is used to assess the distribution of metabolites [monomethylarsonate (MMA), dimethylarsinate (DMA), and unmethylated arsenic (InAs)], as indicators of methylation capacity. W...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.96104620
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:Particulate matter (PM) in outdoor air pollution was recently designated a Group I carcinogen by the International Agency for Research on Cancer (IARC). This determination was based on the evidence regarding the relationship of PM2.5 and PM10 to lung cancer risk; however, the IARC evaluation did not include ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,meta分析,评审
doi:10.1289/ehp/1408092
更新日期:2014-09-01 00:00:00
abstract::The assessment of mixture effects of estrogenic agents is regarded as an issue of high priority by many governmental agencies and expert decision-making bodies all over the world. However, the few mixture studies published so far have suffered from conceptual and experimental problems and are considered to be inconclu...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.00108983
更新日期:2000-10-01 00:00:00
abstract::Laboratory animal diets for studies to determine the endocrine-disrupting potential of chemicals are under scrutiny because they can affect both assay control values and assay sensitivity. Although phytoestrogen content is important, we have previously shown that a phytoestrogen-rich diet and a phytoestrogen-free diet...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7039
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue. OBJECTIVES:We aimed to examine the relationship between environmental cadmium exposure and dental caries in children 6-12 years of age. METHODS:We analyzed c...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.10947
更新日期:2008-06-01 00:00:00
abstract::Over the past decade much information has been published on the analysis of organics extracted from treated water. Certain of these organics have been shown to be by-products of the chlorination disinfection process and to possess harmful effects at high concentrations. This has resulted in increased interest in alter...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.824687
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/EHP1910
更新日期:2017-11-20 00:00:00
abstract::We used an improved method for trapping carbon-centered radicals (.R) from the gas-phase to compare radical suites trapped from various tobacco smoke and model smoke systems. Using a nitroxide trap, 3-amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy (3AP), on solid support, we trapped radicals directly from the gas phase, ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.01109765
更新日期:2001-08-01 00:00:00
abstract::The lung epithelium resorbs alveolar fluid through combined action of sodium channels and the sodium pump, Na,K-ATPase. The lung often is exposed to hyperoxia in disease states and hyperoxia generates a mixture of reactive oxygen species. In vivo and in vitro exposure of rat lung and alveolar type II cells, respective...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.98106s51213
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:The association of DDT (dichlorodiphenyltrichloroethane) with breast cancer is controversial, but animal studies directly linking DDT to risk are lacking. Concerns with DDT reside in its environmental persistence, bioaccumulation in breast adipose tissue, and endocrine-disrupting actions. Whereas most attent...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1104327
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Previous studies have examined fine particulate matter (≤ 2.5 μm; PM2.5) and preterm birth, but there is a dearth of longitudinal studies on this topic and a paucity of studies that have investigated specific sources of this exposure. OBJECTIVES:Our aim was to assess whether anthropogenic sources are associ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1307741
更新日期:2014-10-01 00:00:00
abstract::We conducted a 1-year epidemiologic study in Boston, Massachusetts, beginning May 1997, to examine the associations between environmental factors and office workers' health. We recruited 98 subjects (81 females and 17 males) in 21 offices in four office buildings. We conducted environmental sampling every 6 weeks and ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.5697
更新日期:2003-07-01 00:00:00
abstract::There is an increasing interest in the development and validation of biomarkers for use in biochemical/molecular epidemiological studies. Though the area of neurotoxicology has received much attention in the past several years, it still lags behind with regard to the development of biomarkers, particularly those of he...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.96104s155
更新日期:1996-03-01 00:00:00
abstract::Previously, we showed that diesel exhaust particles (DEPs) suppressed pulmonary clearance of Listeria monocytogenes (Listeria) and inhibited the phagocytosis of alveolar macrophages and their response to Listeria in the secretion of interleukin (IL)-1 beta, tumor necrosis factor alpha, and IL-12. In this report we exa...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.5709
更新日期:2003-04-01 00:00:00
abstract::Endocrine disruption from environmental contaminants has been linked to a broad spectrum of adverse outcomes. One concern about endocrine-disrupting xenobiotics is the potential for additive or synergistic (i.e., greater-than-additive) effects of mixtures. A short-term dosing model to examine the effects of environmen...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8195
更新日期:2005-11-01 00:00:00
abstract::Untreated wastewater from the Mexico City basin has been used for decades to irrigate cropland in the Mezquital Valley, State of Hidalgo, Mexico. Excess irrigation water recharges the near-surface aquifer that is used as a domestic water supply source. We assessed the groundwater quality of three key groundwater sourc...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.99107553
更新日期:1999-07-01 00:00:00
abstract::Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and diethylene glycol monoethyl ether ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.845769
更新日期:1984-08-01 00:00:00
abstract::Rats were instilled intrabronchially with 1 mg UICC amosite suspended in 0.2 mL of filtered saline; control animals received the saline instillation only. Five animals from each group were killed on various days after instillation, up to day 128/129. Total retrieved cell counts and differential cell analysis were perf...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.835141
更新日期:1983-09-01 00:00:00
abstract::The results of our previous and recent work on cadmium metabolism in relation to age and diet are presented. Experiments were performed on albino rats aged 1-26 weeks. In some experiments rats were given different foods (milk, meat, bread) instead of standard rat diet. Some animals received trisodium calcium salt of d...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.845451
更新日期:1984-03-01 00:00:00