Abstract:
:Adrenal involvement by Paracoccidioides brasiliensis was described at necropsies and in many clinical studies, but only in adults. Therefore, the aim of this study was to evaluate adrenal function in children with paracoccidioidomycosis. Twenty-three children with the systemic form of paracoccidioidomycosis were evaluated and divided in two Groups: Group A (n = 8) included children before treatment and Group B (n = 15) children after the end of treatment. Plasma cortisol (basal and after ACTH test), ACTH, renin activity, aldosterone, sodium and potassium were measured. They were within normal range in all cases, except for renin activity and aldosterone, which were elevated in some cases. Group A patients showed basal and post-ACTH cortisol levels significantly greater than Group B patients. The results showed that adrenal function was not compromised in these children with paracoccidioidomycosis.
journal_name
Rev Inst Med Trop Sao Paulojournal_title
Revista do Instituto de Medicina Tropical de Sao Pauloauthors
Pereira RM,Guerra-Júnior G,Tresoldi ATdoi
10.1590/s0036-46652006000600006subject
Has Abstractpub_date
2006-11-01 00:00:00pages
333-6issue
6eissn
0036-4665issn
1678-9946pii
S0036-46652006000600006journal_volume
48pub_type
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journal_title:Revista do Instituto de Medicina Tropical de Sao Paulo
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