Adrenal function in 23 children with paracoccidioidomycosis.

Abstract:

:Adrenal involvement by Paracoccidioides brasiliensis was described at necropsies and in many clinical studies, but only in adults. Therefore, the aim of this study was to evaluate adrenal function in children with paracoccidioidomycosis. Twenty-three children with the systemic form of paracoccidioidomycosis were evaluated and divided in two Groups: Group A (n = 8) included children before treatment and Group B (n = 15) children after the end of treatment. Plasma cortisol (basal and after ACTH test), ACTH, renin activity, aldosterone, sodium and potassium were measured. They were within normal range in all cases, except for renin activity and aldosterone, which were elevated in some cases. Group A patients showed basal and post-ACTH cortisol levels significantly greater than Group B patients. The results showed that adrenal function was not compromised in these children with paracoccidioidomycosis.

authors

Pereira RM,Guerra-Júnior G,Tresoldi AT

doi

10.1590/s0036-46652006000600006

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

333-6

issue

6

eissn

0036-4665

issn

1678-9946

pii

S0036-46652006000600006

journal_volume

48

pub_type

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