Abstract:
PROBLEM:The potential for misidentification of trial participants, leading to misclassification, is a threat to the integrity of randomized controlled trials. The correct identification of study subjects in large trials over prolonged periods is of vital importance to those conducting clinical trials. Currently used means of identifying study participants, such as identity cards and records of name, address, name of household head and demographic characteristics, require large numbers of well-trained personnel, and still leave room for uncertainty. APPROACH:We used fingerprint recognition technology for the identification of trial participants. This technology is already widely used in security and commercial contexts but not so far in clinical trials. LOCAL SETTING:A phase 2 cholera vaccine trial in SonLa, Viet Nam. RELEVANT CHANGES:An optical sensor was used to scan fingerprints. The fingerprint template of each participant was used to verify his or her identity during each of eight follow-up visits. LESSONS LEARNED:A system consisting of a laptop computer and sensor is small in size, requires minimal training and on average six seconds for scanning and recognition. All participants' identities were verified in the trial. Fingerprint recognition should become the standard technology for identification of participants in field trials. Fears exist, however, regarding the potential for invasion of privacy. It will therefore be necessary to convince not only trial participants but also investigators that templates of fingerprints stored in databases are less likely to be subject to abuse than currently used information databases.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
SonLa Study Group.doi
10.2471/blt.06.031070subject
Has Abstractpub_date
2007-01-01 00:00:00pages
64-7issue
1eissn
0042-9686issn
1564-0604pii
S0042-96862007000100014journal_volume
85pub_type
杂志文章abstract::In many health facilities in east Africa, haemoglobin estimation is performed using visual colour comparison methods. Efforts to establish colorimetric methods face numerous constraints, including the unavailability of standards for quality control. In contrast, the alkaline haematin D-575 method for haemoglobin estim...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The development of several DDT-resistant strains of Anopheles atroparvus is described. They were selected by larval treatment only (RL), selection of larval and adult females (RLAF), and selection of adult females and males (RAFM). Their rate of DDT-resistance was measured in the larval and adult states (mainly in the...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1959-01-01 00:00:00
abstract::The study procedures and the results of blood pressure screening from 8 centres are reported. Data are also presented on age, sex, sexual maturity for girls, height, weight, Quetelet's index, smoking, and use of antihypertensive drugs for 92.1% of the 18 609 children born in 1964 in the 8 districts and surveyed in 197...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::A WHO-coordinated study of the community control of hypertension in six countries (Cuba, Finland, France, Italy, Mongolia and Portugal) has shown that a comprehensive approach clearly improves the care of hypertensives in various populations. Hypertension control programmes were individually designed in each country a...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:PROBLEM:In many countries, the tuberculosis (TB) annual case detection rate is below the target of 70%. In the Lao People's Democratic Republic in 2005, it did not exceed 55% APPROACH:The DOTS strategy promotes passive case detection of TB. In order to increase the detection rate, we validated a questionnaire targetin...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.038539
更新日期:2007-09-01 00:00:00
abstract::Since the appearance of DDT-resistance in houseflies in 1947, over 30 mosquito species have developed resistance to this and other commonly used insecticides. Much knowledge has been gained concerning the mechanism of resistance in insects but, in general, this phenomenon cannot be explained in terms of a single facto...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::Evaluation of disease outcome is central to the assessment of tuberculosis (TB) control programmes. In the study reported in this article we examined the factors influencing the measurement of outcome, survival rates during and after treatment, smear conversion rates, and relapse rates for patients diagnosed with TB i...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Tuberculosis (TB) is a major public health problem in eastern Europe. Since 1990, the incidence rates of TB have continued to increase in Belarus, the Russian Federation, the Ukraine and the central Asian republics of Kazakhstan, Kyrgyzstan, Tajikistan and Uzbekistan. Eastern Europe, and in particular the Russian Fede...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:10.2471/blt.06.034991
更新日期:2008-02-01 00:00:00
abstract::With an increasing number of malaria eradication programmes approaching or entering the consolidation phase, the epidemiological features of disappearing malaria are getting better known and defined. At the same time, the old classical methods of measuring malaria prevalence have become inadequate and new methods for ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::The authors have attempted to prepare lysed BCG vaccines retaining the protective antigens of the BCG cell wall and yet eliciting in experimental animals limited sensitivity to the tuberculin substances, the advantage sought being to retain the usefulness of the tuberculin following vaccination as an indicator of supe...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::In this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of Vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. It is shown that parent strains possessing a fertility factor (designated as the P factor) function...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::The authors first discuss the principle of the Treponema pallidum immobilization (TPI) test, considered both as a qualitative and as a quantitative test, and then various specific aspects of passage of the Nichols strain of treponeme in rabbit testes. A number of important technical details and modifications in the te...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::Forecasts of tuberculosis morbidity and mortality are presented for the decade 1990-99. An estimated 88 million new cases of tuberculosis, of which 8 million will be attributable to HIV infection, will occur in the world during the decade; 30 million people are predicted to die of tuberculosis in the same period, incl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Thiomersal-iodine-formalin (TIF) has been used as a faecal preservative in many prevalence surveys of intestinal helminths and protozoa. In helminth surveys, however, estimates of worm burden are no less essential than those of prevalence. Direct-smear and dilution egg-counting techniques, using fresh faeces, have bee...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::An epidemic of poliomyelitis took place in British Guiana during the winter of 1962-63. A total of 485 paralytic cases occurred over a 10-week period, 90% in children under 5 years of age.The attack rate for the total population of more than half-a-million persons was 86.5 per 100 000. Type 1 poliovirus was isolated f...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::In order to study the role of genetic factors in susceptibility to leprosy infection, the prevalence of leprosy in 118 pairs of Burmese villages different distances apart was investigated. The distribution pattern of the correlation coefficients for leprosy rates was compared with that known to occur for genetic marke...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Tumours of the pancreas occur most commonly in dogs and cats and only rarely in other domestic species. The incidence of neoplasms, both exocrine and endocrine, increases with age. Exocrine adenocarcinomas are the most common malignant tumours and have three fairly distinct morphological patterns: small tubular, large...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::A collaborative study on the laboratory diagnosis of trachoma was carried out in three laboratories. A standardized complement fixation (CF) test with chlamydial (bedsonial) group antigen was found to be highly reproducible. The results obtained by different laboratories using the method and reagents suggested by the ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-05-01 00:00:00
abstract::Picornavirus particles and serotype-specific neutralizing antibody were demonstrated in tears collected during early onset of acute haemorrhagic conjunctivitis. Virus particles deposited from tears by airfuge ultracentrifugation and stained with potassium phosphotungstate were easily recognized by electron microscopy....
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the implementation of a programme to provide primary care physicians for remote and deprived populations in Brazil. METHODS:The Mais Médicos (More Doctors) programme was launched in July 2013 with public calls to recruit physicians for priority areas. Other strategies were to increase primary car...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.16.178236
更新日期:2017-02-01 00:00:00
abstract::Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphoteric...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To determine areas of low vaccination coverage in five cities in Bangladesh (Chittagong, Dhaka, Khulna, Rajshahi, and Syedpur). METHODS:Six studies using lot quality assurance sampling were conducted between 1995 and 1997 by Basic Support for Institutionalizing Child Survival and the Bangladesh National Expa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The spot hybridization assay for the detection of Plasmodium falciparum reported here uses as probe a repetitive DNA sequence from this species and exhibits a high degree of species specificity. Isolates from African, Asian, and South American patients were positive in the assay and gametocytes could be detected at th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::In South-East Asia in recent years urbanization has proceeded rapidly. Because of limited financial resources it has seldom been possible to provide sufficient sanitation; this has led to conditions favourable to the breeding of Culex pipiens fatigans. The density of C. p. fatigans is higher in urban areas than in rur...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::Smallpox vaccinations were performed in a well-vaccinated prison population by multiple-pressure technique and by intradermal jet injection using serial dilutions of vaccine. A total of 140 subjects were divided into groups, and each group was vaccinated by the multiple-pressure technique or by jet injection using 1 o...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1969-01-01 00:00:00
abstract::Public and political awareness of emerging infectious diseases is growing, as animal and human health specialists work closer together to avert potential outbreaks. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.11.031211
更新日期:2011-12-01 00:00:00
abstract::Toxorhynchites brevipalpis, a predator on larvae of Aedes aegypti and other mosquitos, was successfully colonized in the laboratory. At 25 degrees C, embryonic development was completed within 50 hours of oviposition, while larval and pupal development together took a further 27-41 days. The adult mosquitos mated in c...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-05-01 00:00:00
abstract:OBJECTIVE:To assess the usefulness of the general framework of the smoking epidemic. METHODS:We use lung cancer mortality as an indicator for smoking intensity and employ an age-cohort model to accommodate the long-lasting and cumulative effects. RESULTS:Dutch males have higher risks than Danish males, but the risks ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:PROBLEM:The visit of Pope Francis to the Philippines in January 2015 coincided with a tropical storm. For security reasons, the only road in and out of the area was closed 14.5 hours before the Pope's arrival. This meant that people had to wait for many hours with little shelter at the site. Medical teams in the field ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.158089
更新日期:2015-11-01 00:00:00
abstract::Three diphtheria toxoid preparations, fractionated at various concentrations of ammonium sulfate, having various grades of purity, and showing striking differences in immunizing potency when compared at the same Lf dose, were examined for similarity of the effective constituents in the fractions. No evidence of deviat...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1954-01-01 00:00:00