Abstract:
:Proton pump inhibitors (PPIs) are widely used for the treatment of gastroesophageal reflux disease, as well as other acid-related disorders. Omeprazole, lansoprazole, pantoprazole, rabeprazole and esomeprazole effectively suppress gastric acid secretion by blocking the gastric acid pump, H+/K+ -adenosine triphosphatase (ATPase). Understanding the pharmacokinetic properties of PPIs and examining the pharmacogenetic differences may help clinicians to optimize PPI therapy and to perform individual treatment, especially in non-responder patients with GERD or ulcer or after failed eradication therapy.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Mullner K,Molnar B,Tulassay Zdoi
10.1556/OH.2007.27902subject
Has Abstractpub_date
2007-03-25 00:00:00pages
543-51issue
12eissn
0030-6002issn
1788-6120journal_volume
148pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract::A total of 93 breast cyst fluids (BCF) obtained by needle aspiration of women suffering from gross cystic mastopathy was hormonally investigated. The mean age of the patients was 45 years (range 27-65). Estradiol (E2), progesterone (PROG), testosterone (TE), prolactin (PROL), estriol (E3), dehydroisoandrosterone and i...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1994-04-24 00:00:00
abstract:INTRODUCTION AND AIM:To implement lipiodol as a fiducial marker of the tumor bed for image-guided radiotherapy with simultaneous integrated boost technique as part of radiochemotherapy for muscle invasive bladder tumors. METHOD:Since April 2016, radiochemotherapy was performed in 3 male patients with muscle invasive, ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2017.30904
更新日期:2017-12-01 00:00:00
abstract::The paper gives an introduction to the basis and quality control of a relatively new imaging method. First the different kinds of SPECT instruments, and then the aspects of diagnostic application are described. Details are given on examinations of the central nervous system, the abdomen, the hearth and the skeletal sy...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-19 00:00:00
abstract::Clinical presentation at diagnosis and disease course of both Crohn's disease (CD) and ulcerative colitis (UC) are heterogeneous and variable over time. During follow up, intestinal strictures or perforation may eventually develop at most patients with CD, and significant number of patients will undergo surgery. Much ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2010.28813
更新日期:2010-02-21 00:00:00
abstract::Primary spinal tumors are rare diseases. Primary spinal tumor registry would be useful to help decision making in this complex field of spine surgery. In this article the authors present the latest findings from the Primary Spinal Tumor Registry at the National Centre for Spinal Disorders, Hungary. The registry is bas...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2014.29920
更新日期:2014-05-11 00:00:00
abstract::Of 15,000 post-mortem examinations performed in a general hospital between 1977-85 primary symmetric intracerebral calcification i. e. Fahr's disease was found in 4 cases. The pathological characteristics of the cases are described and the clinical, radiological and endocrinological aspects of the disease are discusse...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-08 00:00:00
abstract:UNLABELLED:The associations of the ABO- and Rh-blood groups, the serum cholesterol and the extent of the coronary artery disease were examined in 653 patients who underwent coronary angiography between 1980 and 1985 in the Hungarian Institute of Cardiology. CONCLUSIONS:1. among the patients with positive coronarograph...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-04-09 00:00:00
abstract::The screening and special management of high risk patient, is possible strategy to reduce the high morbidity and mortality of stroke. In the II. district of Budapest we examined high vascular risk patients cooperating with general practitioners. We let the severity of risk with arithmetic of the cumulative risk index....
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2000-04-23 00:00:00
abstract::The authors present the computer dynamic pedobarographic analyse method of the diabetic foot with case reports. The diabetic foot is described in the literature by interdisciplinar teams, and the authors recommend this method in the identification of the high pressure areas of the foot. By this way the orthotic specia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-02 00:00:00
abstract::Five patients suffering from transient myocardial ischemia of the newborn are discussed. The role of two-dimensional doppler-echocardiography is emphasized in establishing the diagnosis. Tricuspid insufficiency due to perinatal asphyxia can be detected easier by ultrasound than by any other cardiac examination. Cardia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1991-02-03 00:00:00
abstract:INTRODUCTION:The accreditation system for health care providers was developed in Hungary aiming to increase safety, efficiency, and efficacy of care and optimise its organisational operation. AIM:The aim of this study was to assess changes of organisational culture in pilot institutes of the accreditation program. ME...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2016.30556
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:It is known that hyperhomocystinemia is an independent risk factor for development of atherosclerosis. In end stage renal disease the frequency of hyperhomocystinemia is much greater than in normal populations. AIM:In this study homocystein (Hcy), folic acid and vitamin B12 concentrations were determined in...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2002-07-07 00:00:00
abstract:INTRODUCTION:For the primary and secondary prevention of thromboembolic events are used the oral anticoagulants, the drugs having a low therapeutic index and frequent bleeding complication rate. Establishing the proper therapeutic dose of these drugs for different patients is complicated by a variety of conditions, suc...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2005-04-17 00:00:00
abstract:INTRODUCTION:Healthcare associated infections and antimicrobial use are common among residents of long-term care facilities. Faced to the lack of standardized data, the European Centre for Disease Prevention and Control funded a project with the aim of estimating prevalence of infections and antibiotic use in European ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2014.29876
更新日期:2014-06-08 00:00:00
abstract::The pathogenicity and virulence of 3 strains of Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus saprophyticus, respectively were studied in BALB/c mice by intraperitoneal (ip) challenge using 4 bacterial suspensions of different colony forming units (CFU) of each strain. Strains were isolate...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1992-07-05 00:00:00
abstract::Improvement of muscle mass and force which got depleted by inactivity or pathological processes is one of the aims and also a prerequisite of a rehabilitative intervention. Metabolically active larger and stronger muscles diminish the cardiovascular risk, permit the aerobic preventive and rehabilitative activities and...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2005-09-18 00:00:00
abstract::The authors examined the characteristics of old suicide attempters (over 65 years) with special regard to organic and depressive disorders and sociodemographic features. Within the framework of the WHO/EURO Multicentre Study on Parasuicide data of 849 suicide attempts were collected during three years. Comparing old a...
journal_title:Orvosi hetilap
pub_type: 杂志文章,多中心研究
doi:
更新日期:2001-06-03 00:00:00
abstract::Polymyositis-dermatomyositis is a rare systemic autoimmune disease which belongs to the class of idiopathic inflammatory myopathies. The disease exhibits high inter-individual variability, but chronic myositis is a common feature. As different manifestations often appear in atypical forms, establishing the precise dia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2012.29300
更新日期:2012-03-25 00:00:00
abstract::Clinical data on the risk factors, incidence, consequences and current treatment options of venous thromboembolism are reviewed. Current guidelines advise anticoagulant treatment for a few weeks or months in immobilized patients treated in hospital, and after major surgery. The initial treatment is based on heparin, f...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2011.29140
更新日期:2011-06-19 00:00:00
abstract::When taken during pregnancy, the earlier types of contraceptive pills had a direct teratogenic effect on the female fetus, causing the masculinization syndrome. Presently available pills, which are of different composition and given in smaller doses, do not have a direct teratogenic effect when taken during pregnancy...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1980-01-06 00:00:00
abstract::The authors report about the elimination of foreign bodies fixed in the oesophagus and aspirated into the right main bronchus. They discuss the diagnostic work and the ways of its elimination. They emphasize the importance of cooperation between the endoscopist and the surgeon. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1992-07-12 00:00:00
abstract::Összefoglaló. A malignus csonttumorok sebészi ellátása során kialakuló szegmentális csontdefektusok pótlása fontos szempont a végtagmegtartó sebészetben. Felnőttkorban a megoldás rendszerint tumorprotézis beültetése, 10 évesnél fiatalabb gyermekeknél azonban ez nehezen alkalmazható módszer a kis csontméret és az igen ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31767
更新日期:2020-11-08 00:00:00
abstract::The healing properties of sunlight has been known for millennia, however the gradual deterioration of the ozone layer and the increased use of sun tanning beds in recent decades are causing an increase in skin damaging ultraviolet exposure. In this article the most common photodermatoses and the principles of their tr...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2016.30335
更新日期:2016-01-17 00:00:00
abstract:CASE REPORT:A 47 year old female with severe deficiency of three limbs visited our Genetic Counselling Clinic and asked us to give her a certificate that her complex limb deficiency was caused by thalidomide (Contergan). According to her explanation, her mother used this drug during pregnancy which was given to her by ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2009.28641
更新日期:2009-06-21 00:00:00
abstract:INTRODUCTION:Nowadays doctor-patient consultation is not limited to personal appointments, there are new technical possibilities to keep contact. AIM:The aim of our study was to examine the way in which the doctor and patient interact with each other between two personal consultations and how the patients would like t...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2018.31209
更新日期:2018-12-01 00:00:00
abstract::Polycystic ovary syndrome is the most frequent endocrine disease among women of reproductive age. It is associated with increased risks of various metabolic disorders and complications. most recent data suggest that women suffering from polycystic ovary syndrome are most exposed to several psychological problems. It h...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2014.30024
更新日期:2014-11-23 00:00:00
abstract::The authors present the case history of a 2 year old child suffering from nesidioblastosis. Severe non-ketotic symptomatic hypoglycaemia developed within the first hour of birth. Diagnosis of nesidioblastosis was confirmed by high insulin concentration accompanying hypoglycaemia, the increase in blood glucose level af...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-23 00:00:00
abstract::Developments in the fields of laser technology and application have significantly broadened its clinical use over the past two decades. As lasers became more smaller, more reliable and less expensive, dermatology will benefit new laser-based therapeutic and diagnostic methods. Relevant laser systems and their clinical...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-04-30 00:00:00
abstract::The literature of breast-screening is vastly large, and enlarges by newer publications permanently. This summary can only be confined to publish data, with arbitrary selection. The mass-screening of complaintless and symptomless persons for early recognition of certain illnesses is to be completed according to distric...
journal_title:Orvosi hetilap
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:2003-02-16 00:00:00
abstract::Follicular lymphoma is one of the most common indolent nodal non-Hodgkin's lymphomas. The follicular lymphoma should be differentiated from other nodal non-germinal centre derived lymphomas. Since bcl-2 gene translocation can be detected in 80-90% of the cases, it could be used for the confirmation of the diagnosis, m...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-16 00:00:00