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Are large nonfunctional kidneys risk factors for posttransplantation urinary tract infection in patients with end-stage renal disease due to autosomal dominant polycystic kidney disease?

Abstract：

OBJECTIVES:The objective of this study was to evaluate the effect of bilateral nephrectomy on posttransplantation urinary tract infection (UTI) among patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (ADPKD). METHODS:In a retrospective case-control design, 62 patients with ESRD with ADPKD were divided into 2 groups: (A) 24 patients who underwent bilateral nephrectomies, and (B) 38 patients in whom bilateral nephrectomies had not been done. Pretransplantation and posttransplantation urine cultures were evaluated for UTI. RESULTS:Sixty-two patients with ESRD with ADPKD were enrolled in this study. The average age was 42 years (range, 6-60 years). Forty patients (64.5%) were male and 22 (35.5%) were female. The mean duration of hemodialysis was 24 months (range, 2-120 months), which was the same for both groups. Bilateral nephrectomies were done for 24 participants (38.7%). There were 38 patients (61.3%) in group B who did not have the operation. UTI occurred in 23 patients (37.1%): 6 patients (25%) in group A and 17 patients (44.7%) in group B. The incidence of UTI was not statistically different between the 2 groups (P>.05). Furthermore, no relationship was found between age, gender, blood group, and UTI in patients with ADPKD (P>.05). CONCLUSION:According to our study, the presence of large nonfunctional kidneys is not a risk factor for posttransplantation UTI in patients with ADPKD and ESRD.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Salehipour M,Jalaeian H,Salahi H,Bahador A,Davari HR,Nikeghbalian S,Sagheb MM,Raiss-Jalali GA,Roozbeh J,Behzadi S,Janghorban P,Sepas HN,Malek-Hosseini SA

doi

10.1016/j.transproceed.2007.02.058

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

887-8

issue

4

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(07)00259-X

journal_volume

39

pub_type

杂志文章

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