Specificity of the suppressor cell activity of intestinal lymphocytes.

Abstract:

:Experiments were designed to examine the functional characteristics of lymphocytes harvested from the human intestine. Lymphocytes were harvested from the intestines of patients undergoing intestinal resection for a variety of gut disorders. The mitogenic and allogeneic responses of gut lymphocytes were found to be comparable with the response of peripheral blood lymphocytes. Intestinal suppressor cell activity was found to be more specific against other intestinal lymphocytes than peripheral mononuclear cells. The regulation of the intestinal immune response in various bowel disorders may be determined at a local level to a greater degree than had been previously appreciated.

journal_name

Am J Surg

authors

Smith EB,Leapman SB,Filo RS,Jesseph JE,Smith PG

doi

10.1016/0002-9610(83)90184-8

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

164-8

issue

1

eissn

0002-9610

issn

1879-1883

pii

0002-9610(83)90184-8

journal_volume

145

pub_type

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