Low signal intensity and increased anisotropy on magnetic resonance imaging in the white matter lesion after head trauma: unrecognized findings of diffuse axonal injury.

abstract：:Long-term trials have demonstrated the continued efficacy of interferon (IFN) beta treatment in patients with relapsing-remitting (RR) multiple sclerosis (MS) during prolonged administration. The objective of the work was to evaluate the effects of reducing IFN beta administration frequency and total weekly dose in pa...

journal_title：Journal of the neurological sciences

authors： Barbero P,Verdun E,Bergui M,Pipieri A,Clerico M,Cucci A,Ricci A,Bergamasco B,Durelli L

更新日期：2004-07-15 00:00:00

abstract：:McLeod syndrome is a rare X-linked disorder involving neurological defects and acanthocytosis. We examined the XK gene in three patients with neuroacanthocytosis, one of whom had cardiomyopathy, and his symptoms were very similar to those of McLeod syndrome. We found two new transversions (C to G at codon 204 and G to...

journal_title：Journal of the neurological sciences

authors： Shizuka M,Watanabe M,Aoki M,Ikeda Y,Mizushima K,Okamoto K,Itoyama Y,Abe K,Shoji M

更新日期：1997-09-10 00:00:00

abstract：:The purpose of this study was to compare magnetic resonance imaging (MRI) features and proton MR spectroscopy (1H-MRS) patterns of multiple sclerosis (MS) plaques in order to define the metabolic substrate in different lesion subtypes. Combined MRI and single-voxel 1H-MRS investigation was performed in 54 MS patients ...

journal_title：Journal of the neurological sciences

authors： Simone IL,Tortorella C,Federico F,Liguori M,Lucivero V,Giannini P,Carrara D,Bellacosa A,Livrea P

更新日期：2001-01-01 00:00:00

abstract：:The clinical value and practical application of the electrically induced BC reflex was investigated in 40 patients with traumatic or compressive lesions of the conus medullaris or cauda equina. It was shown that the BC reflex was either absent or delayed depending upon the invovlement of the sacral 2--4 spinal and rad...

journal_title：Journal of the neurological sciences

authors： Ertekin C,Reel F,Mutlu R,Kerküklü I

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:We estimated the extent and pattern of cardiovascular autonomic dysfunction in dementia with Lewy bodies (DLB) as compared with that in Parkinson's disease (PD). METHODS:We performed meta-iodobenzylguanidine ((123)I-MIBG) scintigraphy of the heart and hemodynamic autonomic function testing using the Valsalva...

journal_title：Journal of the neurological sciences

authors： Oka H,Morita M,Onouchi K,Yoshioka M,Mochio S,Inoue K

更新日期：2007-03-15 00:00:00

abstract：:Clinical and electrophysiological observations have been carried out on 12 patients with myotonic dystrophy. Neurological examination showed that the tendon reflexes were absent or weak in almost all cases, whereas the cutaneous reflexes were normal. Examination of both deep and superficial sensibility gave normal res...

journal_title：Journal of the neurological sciences

authors： Messina C,Tonali P,Scoppetta C

更新日期：1976-12-01 00:00:00

abstract：:Antibodies to the myelin-associated glycoprotein (MAG) are implicated in the pathogenesis of an acquired demyelinating polyneuropathy. We studied IgM affinity to MAG in 18 patients with anti-MAG antibodies. Binding of sera was tested for anti-MAG immunoreactivity in central nervous system (CNS) by ELISA and in CNS and...

journal_title：Journal of the neurological sciences

authors： Fluri F,Ferracin F,Erne B,Steck AJ

更新日期：2003-03-15 00:00:00

abstract：OBJECTIVE:To identify and characterize cup to disc ratio (CDR) and related optic nerve head abnormalities in multiple sclerosis (MS) using spectral domain optical coherence tomography (OCT). BACKGROUND:While CDR is routinely assessed by ophthalmologists in the evaluation of glaucoma, CDR and related optic nerve head m...

journal_title：Journal of the neurological sciences

authors： Syc SB,Warner CV,Saidha S,Farrell SK,Conger A,Bisker ER,Wilson J,Frohman TC,Frohman EM,Balcer LJ,Calabresi PA

更新日期：2011-03-15 00:00:00

abstract：:It is now possible to diagnose patients with multiple sclerosis earlier than previously due to the integration of MRI parameters into the diagnostic criteria. This provides a window of opportunity to treat patients with disease-modifying treatments before clinically-manifest tissue destruction and disability has emerg...

journal_title：Journal of the neurological sciences

authors： Tintoré M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Although adoption of new clinical criteria for dementia with Lewy bodies (DLB) leads to an increase in the proportion of patients diagnosed with probable DLB, the sensitivity of clinical diagnostic criteria of DLB is low, and there are no generally accepted clinical or imaging biomarkers to distinguish DLB f...

journal_title：Journal of the neurological sciences

authors： Kim JS,Park HE,Oh YS,Song IU,Yang DW,Park JW,Lee KS

更新日期：2015-10-15 00:00:00

abstract：:Paired serum and cerebrospinal fluid (CSF) samples from 70 patients with inflammatory and non-inflammatory neurological diseases, as well as 10 sera from patients with primary antiphospholipid syndrome (PAS), six of which presented with cerebrovascular ischemic syndromes, were studied for the presence of anticardiolip...

journal_title：Journal of the neurological sciences

authors： Gallo P,Sivieri S,Ferrarini AM,Giometto B,Ruffatti A,Ritter E,Chizzolini C,Tavolato B

更新日期：1994-03-01 00:00:00

abstract：:As we learn more about the relationships between depression and cerebrovascular disease (CVD), a complex picture is emerging in which the chain of causality seems to spiral on itself: progressive or focal brain damage, cognitive impairment, depressive symptoms, dementia, and cardiovascular diseases, all seem to be lia...

journal_title：Journal of the neurological sciences

authors： Dieguez S,Staub F,Bruggimann L,Bogousslavsky J

更新日期：2004-11-15 00:00:00

abstract：PURPOSE:This study aimed to develop a conceptual understanding of the specific characteristics of palliative care in neurology and the challenges of providing palliative care in the setting of neurological illness. METHOD:The study was conducted at London Health Sciences Centre in Canada using grounded theory methodol...

journal_title：Journal of the neurological sciences

authors： Gofton TE,Chum M,Schulz V,Gofton BT,Sarpal A,Watling C

更新日期：2018-02-15 00:00:00

abstract：:Monthly dual-echo spin-echo (SE) and enhanced magnetic resonance imaging (MRI) after the injection of a standard dose (SD) of gadolinium (Gd) is the conventional approach to monitor short-term disease activity in multiple sclerosis (MS). In this study, the sensitivity of this approach in detecting active lesions in MS...

journal_title：Journal of the neurological sciences

authors： Filippi M,Mastronardo G,Bastianello S,Rocca MA,Rovaris M,Gasperini C,Pozzilli C,Comi G

更新日期：1998-07-15 00:00:00

abstract：:We describe a patient with progressive aphemia with agrammatism that was later overlaid with buccofacial apraxia and pseudobulbar palsy. Pathological findings were consistent with those of classic Pick's disease with argyrophilic inclusions and neuronal achromasia, except for restricted cortical atrophy in the frontal...

journal_title：Journal of the neurological sciences

authors： Sakurai Y,Murayama S,Fukusako Y,Bando M,Iwata M,Inoue K

更新日期：1998-08-14 00:00:00

abstract：:A 53-year old woman developed slowly progressive dysarthria, mild enlargement of the tongue and dysphagia since 1 year ago. All neurological differential diagnoses that could have explained the bulbar symptoms were excluded. The swallowing sequence was pathologic and immunoglobulins were markedly reduced. A bone marro...

journal_title：Journal of the neurological sciences

authors： Finsterer J,Wogritsch C,Pokieser P,Vesely M,Ulrich W,Grisold W,Mamoli B

更新日期：1997-04-15 00:00:00

abstract：OBJECTIVE:GM1 ganglioside has been suggested as a treatment for Parkinson's disease (PD), potentially having symptomatic and disease modifying effects. The current pilot imaging study was performed to examine effects of GM1 on dopamine transporter binding, as a surrogate measure of disease progression, studied longitud...

journal_title：Journal of the neurological sciences

authors： Schneider JS,Cambi F,Gollomp SM,Kuwabara H,Brašić JR,Leiby B,Sendek S,Wong DF

更新日期：2015-09-15 00:00:00

abstract：:This report concerns the expression of ubiquitin in anterior horn cells of various subgroups of adult and infantile motor neuron disease (MNDs); immunohistochemical techniques were employed. Ubiquitin-positive skein-like inclusions (SLIs) were found in all cases of adult-onset amyotrophic lateral sclerosis (ALS), incl...

journal_title：Journal of the neurological sciences

authors： Matsumoto S,Goto S,Kusaka H,Imai T,Murakami N,Hashizume Y,Okazaki H,Hirano A

更新日期：1993-04-01 00:00:00

abstract：:Dietary supplements containing Ephedra used for weight loss and physical performance enhancement such as "herbal ecstasy" are widely available, and it is estimated that at least 1% of the adult population have taken these products. Ephedra products including Ephedra alkaloids such as phenylpropanolamine or other ephed...

journal_title：Journal of the neurological sciences

authors： Chen C,Biller J,Willing SJ,Lopez AM

更新日期：2004-01-15 00:00:00

abstract：OBJECTIVES:Tumor necrosis factor-alpha inhibitors (TNFα-I) are biological agents used in the treatment of rheumatologic disorders. TNFα-I have been associated with demyelinating disorders mimicking multiple sclerosis. The goal of this report is to illustrate cases of myelopathy which developed during the use of TNFα-I....

journal_title：Journal of the neurological sciences

authors： Barreras P,Mealy MA,Pardo CA

更新日期：2017-02-15 00:00:00

abstract：:The excitotoxin kainic acid (10 nmol/microliter) was used to produce bilateral lesions in the nucleus basalis magnocellularis (NBM) of rats which provides extensive cholinergic innervation to the cerebral cortex. The behavioral effects of physostigmine, THA (9-amino-1,2,3,4-tetrahydroacridine hydrochloride) and NIK-24...

journal_title：Journal of the neurological sciences

authors： Ueki A,Miyoshi K

更新日期：1989-03-01 00:00:00

abstract：:Room tilt illusion, a misperception that the entire room is tilted, is a rare but nonspecific neurological symptom. We report a patient with Parkinson's disease who developed typical room tilt illusion. Single photon emission computed tomography demonstrated hypoperfusion of the posterior area of the right intrapariet...

journal_title：Journal of the neurological sciences

authors： Hayashi R,Yamaguchi S,Katsumata Y,Mimura M

更新日期：2009-12-15 00:00:00

abstract：:Axonal degeneration plays an important role in the accumulation of disability in patients with multiple sclerosis (MS). Pathological studies have demonstrated axonal damage, particularly in areas of acute inflammation and demyelination, and in chronic lesions. Axonal loss and its progression, which is associated with ...

journal_title：Journal of the neurological sciences

authors： Silber E,Sharief MK

更新日期：1999-11-15 00:00:00

abstract：:The analysis of human skeletal muscle mitochondria revealed a progressive decline in mitochondrial respiratory chain function with age. The activities affected to the greatest extent were those of complexes I and IV which were decreased by 59% and 47% respectively between the ages of 20-30 years and 60-90 years of age...

journal_title：Journal of the neurological sciences

authors： Cooper JM,Mann VM,Schapira AH

更新日期：1992-11-01 00:00:00

abstract：:A 66-year-old man presented with right cerebellar infarction and ischemic lesions in the left dorsal thalamus and right upper parietal lobe. Angiography showed occlusion of the right internal carotid artery proximal to an ipsilateral proatlantal artery type I, 70% stenosis of the left internal carotid artery, and apla...

journal_title：Journal of the neurological sciences

authors： Kolbinger R,Heindel W,Pawlik G,Erasmi-Körber H

更新日期：1993-07-01 00:00:00

abstract：:The occurrence of neuropathy in 5 cases of inclusion body myositis (IBM) was studied. The intramuscular nerve branches showed variable ultrastructural changes in all cases. The observed changes were loss of axons, wallerian degeneration and axon terminal atrophy. EMG with concentric needles showed myopathic motor unit...

journal_title：Journal of the neurological sciences

authors： Lindberg C,Oldfors A,Hedström A

更新日期：1990-11-01 00:00:00

abstract：:The clinical, genetic and electrophysiological study of 3 patients with an association of a neuronal form of Charcot-Marie-Tooth Disease (CMTD) with a syndrome of continuous motor unit activity (CMUA) are reported, with light and electron microscopy of muscle and sural nerve biopsies in 2 patients. The unusual clinica...

journal_title：Journal of the neurological sciences

authors： Vasilescu C,Alexianu M,Dan A

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:This study aimed to provide an updated overview of primary central lymphoma (PCL) using a large cohort of 33 years. That being said, we attempted to examine the patient demographics, management plans and their outcome, causes of death and the time trends in overall incidence and mortality rates of these patient...

journal_title：Journal of the neurological sciences

authors： Ghozy S,Dibas M,Afifi AM,Hashim MA,Abbas AS,Abdel-Daim MM,Phan K

更新日期：2020-08-15 00:00:00

abstract：:Corticosteroids (Cs) are widely used for treatment of multiple sclerosis (MS) acute relapses because of the potent immunosuppressive and anti-inflammatory properties. As for patients with relapsing-remitting (RR) MS, short-term administrations of Cs markedly less severity of symptoms and promote faster recovery of cli...

journal_title：Journal of the neurological sciences

authors： Pozzilli C,Marinelli F,Romano S,Bagnato F

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND AND AIMS:Both vascular disease and diabetes type 2 (DM2) decrease cognitive functioning in elderly people. It is uncertain if DM2 affects cognition independent of vascular disease. In patients with symptomatic arterial disease, we studied the effect of DM2 on cognition and identified clinical and radiologica...

journal_title：Journal of the neurological sciences

authors： Tiehuis AM,Mali WP,van Raamt AF,Visseren FL,Biessels GJ,van Zandvoort MJ,Kappelle LJ,van der Graaf Y,SMART Study Group.

更新日期：2009-08-15 00:00:00