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A multibiomarker approach in barramundi (Lates calcarifer) to measure exposure to contaminants in estuaries of tropical North Queensland.

Abstract：

:A suite of biomarkers were measured in barramundi (Lates calcarifer) from five North Queensland estuaries along a perceived pollution gradient. The biomarkers selected were 7-ethoxyresorufin-O-deethylase (EROD), cytochrome P450, fluorescent aromatic compounds (FACs), DNA integrity, RNA:DNA ratio, cholinesterase activity (ChE), condition factor and hepatosomatic index. The resulting database was subjected to uni- and multi-variate analyses in order to assess the most suitable biomarkers to assess pollution in North Queensland estuaries and to classify the environmental quality of the sites. Principal components analysis (PCA) on the biochemical markers revealed that EROD, EROD/P450, DNA damage and to a lesser extent ChE and FACs were found to be responsive to contaminants in the environment while cytochrome P450, condition factor and the hepatosomatic index were found to be less responsive biomarkers. This study has demonstrated the utility of applying a multibiomarker approach in conjunction with traditional analysis of contaminants in providing valuable information in environmental risk assessment.

journal_name

Mar Pollut Bull

journal_title

Marine pollution bulletin

authors

Humphrey CA,Codi King S,Klumpp DW

doi

10.1016/j.marpolbul.2007.06.004

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

1569-81

issue

10

eissn

0025-326X

issn

1879-3363

pii

S0025-326X(07)00217-2

journal_volume

54

pub_type

杂志文章

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