Local reactions after i.v. injections of diazepam, flunitrazepam and isotonic saline.

Abstract:

:Local reactions after i.v. injection of diazepam, flunitrazepam and isotonic saline were studied in patients who received extradural analgesia or general anaesthesia. The frequency of thrombophlebitis on the 1st, 3rd and 5th days after the injection of diazepam was 2.1%, 17.0% and 14.9% respectively, after flunitrazepam 10.0%. 10.0% and 14.0%, and after saline 0%, 6.7% and 4.4%. The differences between the groups were not statistically significant (P > 0.05). One month after the injection 15.6% in the diazepam group, 8.5% in the flunitrazepam group and 9.3% in the saline group had pain or tenderness in the arm used for the injection.

journal_name

Br J Anaesth

authors

Mikkelsen H,Hoel TM,Bryne H,Krohn CD

doi

10.1093/bja/52.8.817

subject

Has Abstract

pub_date

1980-08-01 00:00:00

pages

817-9

issue

8

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)50196-8

journal_volume

52

pub_type

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