Abstract:
:Conclusions based on systematic reviews of randomized controlled trials are considered to provide the highest level of evidence about the effectiveness of an intervention. This overview summarizes the available evidence from systematic reviews on the effects of nonpharmacological and nonsurgical interventions for rheumatoid arthritis (RA). Systematic reviews of studies of patients with RA (aged >18 years) published between 2000 and 2007 were identified by comprehensive literature searches. Methodological quality was independently assessed by 2 authors, and the quality of evidence was summarized by explicit methods. Pain, function, and patient global assessment were considered primary outcomes of interest. Twenty-eight systematic reviews were included in this overview. High-quality evidence was found for beneficial effects of joint protection and patient education, moderate-quality evidence was found for beneficial effects of herbal therapy (gamma-linolenic acid) and low-level laser therapy, and low-quality evidence was found for the effectiveness of the other interventions. The quality of evidence for the effectiveness of most nonpharmacological and nonsurgical interventions in RA is moderate to low.
journal_name
Phys Therjournal_title
Physical therapyauthors
Christie A,Jamtvedt G,Dahm KT,Moe RH,Haavardsholm EA,Hagen KBdoi
10.2522/ptj.20070039subject
Has Abstractpub_date
2007-12-01 00:00:00pages
1697-715issue
12eissn
0031-9023issn
1538-6724pii
ptj.20070039journal_volume
87pub_type
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