Abstract:
:Deficits of semantic cognition in semantic dementia and in aphasia consequent on CVA (stroke) are qualitatively different. Patients with semantic dementia are characterised by progressive degradation of central semantic representations, whereas multimodal semantic deficits in stroke aphasia reflect impairment of executive processes that help to direct and control semantic activation in a task-appropriate fashion [Jefferies, E., & Lambon Ralph, M. A. (2006). Semantic impairment in stroke aphasia vs. semantic dementia: A case-series comparison. Brain 129, 2132-2147]. We explored interactions between these two aspects of semantic cognition by examining the effects of cumulative phonemic cueing on picture naming in case series of these two types of patient. The stroke aphasic patients with multimodal semantic deficits cued very readily and demonstrated near-perfect name retrieval when cumulative phonemic cues reached or exceeded the target name's uniqueness point. Therefore, knowledge of the picture names was largely intact for the aphasic patients, but they were unable to retrieve this information without cues that helped to direct activation towards the target response. Equivalent phonemic cues engendered significant but much more limited benefit to the semantic dementia patients: their naming was still severely impaired even when most of the word had been provided. In contrast to the pattern in the stroke aphasia group, successful cueing was mainly confined to the more familiar un-named pictures. We propose that this limited cueing effect in semantic dementia follows from the fact that concepts deteriorate in a graded fashion [Rogers, T. T., Lambon Ralph, M. A., Garrard, P., Bozeat, S., McClelland, J. L., & Hodges, J. R., et al. (2004). The structure and deterioration of semantic memory: A neuropsychological and computational investigation. Psychological Review 111, 205-235]. For partially degraded items, the residual conceptual knowledge may be insufficient to drive speech production to completion but these items might reach threshold when they are bolstered by cues.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Jefferies E,Patterson K,Ralph MAdoi
10.1016/j.neuropsychologia.2007.09.007subject
Has Abstractpub_date
2008-01-31 00:00:00pages
649-58issue
2eissn
0028-3932issn
1873-3514pii
S0028-3932(07)00327-2journal_volume
46pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract::It is not clear how compound words are represented within the influential framework of the lemma-lexeme theory. Theoretically, compounds could be structured through a multiple lemma architecture, in which the lemma nodes of both the compound and its constituents are involved in lexical processing. If this were the cas...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2012.01.021
更新日期:2012-04-01 00:00:00
abstract::The human brain has evolved a multifaceted fear system, allowing threat detection to enable rapid adaptive responses crucial for survival. Although many cortical and subcortical brain areas are believed to be involved in the survival circuits detecting and responding to threat, the amygdala has reportedly a crucial ro...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107698
更新日期:2020-11-27 00:00:00
abstract::Brain imaging studies have suggested a predominant involvement of prefrontal areas during retrieval of information from working memory (WM). This study used event-related functional magnetic resonance imaging to assess the gradual recruitment of brain areas during verbal WM-retrieval with a parametrically varied modif...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.05.015
更新日期:2006-01-01 00:00:00
abstract::A series of experiments explored the mechanisms determining the encoding and storage of features and objects in visual working memory. We contrasted the effects of three types of visual suffix on cued recall of a display of colored shapes. The suffix was presented after the display and before the recall cue. The latte...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.11.030
更新日期:2011-05-01 00:00:00
abstract::Array-centred and subarray-centred neglect were disambiguated in a group of 116 patients with left neglect by means of a modified version of the Albert test in which the central column of segments was deleted so as to create two separate sets of targets grouped by proximity. The results indicated that neglect was more...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0028-3932(02)00066-0
更新日期:2002-01-01 00:00:00
abstract::Visual motion processing is often attributed to the dorsal visual pathway despite visual motion's involvement in almost all visual functions. Furthermore, some visual motion tasks critically depend on the structural integrity of regions outside the dorsal pathway. Here, based on numerous studies, I propose that visual...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2016.07.018
更新日期:2016-08-01 00:00:00
abstract::We describe two cases of false recognition in patients with dementia and diffuse temporal lobe pathology who report their memory difficulty as being one of persistent déjà vecu--the sensation that they have lived through the present moment before. On a number of recognition tasks, the patients were found to have high ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2004.12.008
更新日期:2005-01-01 00:00:00
abstract::The functional-neuroanatomic relationship that describes the involvement of the parietal cortex in visual search was investigated using repetitive transcranial magnetic stimulation (rTMS; 10 Hz, 500 ms in duration). Twelve adult participants performed feature-based visual search for a unique letter-without eye movemen...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2005.07.014
更新日期:2006-01-01 00:00:00
abstract::This report bears on the behavior of 188 unilateral stroke subjects when administered an aphasia screening test comprising a short interview as well as naming, repetition, word-picture matching and sentence-picture matching tasks. All subjects were unilingual lusophone adult (40 yr of age or older) right-handers. Furt...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(88)90114-5
更新日期:1988-01-01 00:00:00
abstract::Research of the neurobiological bases of learning and memory suggest that these processes are not unitary in nature, but rather that relatively independent neural systems appear to mediate different types of memory. Neurobiological studies, for instance, have identified separable cognitive or "declarative" and stimulu...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/s0028-3932(02)00157-4
更新日期:2003-01-01 00:00:00
abstract::Selective attention to particular aspects of incoming sensory information is enabled by a network of neural areas that includes frontal cortex, posterior parietal cortex, and, in the visual domain, visual sensory regions. Although progress has been made in understanding the relative contribution of these different reg...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2012.02.009
更新日期:2012-05-01 00:00:00
abstract::It was predicted that right-hemisphere lesions cause a more marked deficit of shallow incidental memory than deep incidental or deliberate memory, the degree of the deficits being reversed after left-hemisphere lesions. This hypothesis was studied by measuring memory for words and faces in brain-damaged patients and n...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(87)90133-3
更新日期:1987-01-01 00:00:00
abstract::Two experiments assessed if non-human primates can be meaningfully compared to humans in a non-verbal test of serial recall. A procedure was used that was derived from variations of the Corsi test, designed to test the effects of sequence structure and movement path length in humans. Two baboons were tested in Experim...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.10.003
更新日期:2011-12-01 00:00:00
abstract::In order to understand how experience of an action alters functional brain responses to visual information, we examined the effects of reflex walking on how 10-week-old infants processed biological motion. We gave experience of the reflex walk to half the participants, and did not give this experience to the other hal...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.11.005
更新日期:2019-03-18 00:00:00
abstract::A comparative study of chimpanzee (Pan troglodytes) and capuchin monkey (Cebus apella) cerebellar asymmetry and its relationship to handedness was conducted. Magnetic resonance images of the brain and behavioral data on a coordinated bimanual task were obtained from 16 chimpanzees and 11 capuchins. Chimpanzees display...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2007.02.010
更新日期:2007-06-11 00:00:00
abstract::Apraxia after left inferior parietal lesions has been widely interpreted as evidence of damage or impaired access to representations of tool-use, but most research has investigated pantomime of tool actions, not handling of actual tools. An alternative account is that inferior parietal damage does not affect tool-use ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.01.020
更新日期:2011-04-01 00:00:00
abstract::Greene et al. [12] suggest that Alzheimer's disease (AD) patients approach repeated trials in a learning test as if they are single unrelated trials. Previous research [7] indicates that AD patients do not have explicit memory for item repetition when asked at test how many times a word was presented, but they do show...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(99)00142-6
更新日期:2000-01-01 00:00:00
abstract::The ventral temporal cortex (VTC) contains several areas with selective responses to words, numbers, faces, and objects as demonstrated by numerous human and primate imaging and electrophysiological studies. Our recent work using electrocorticography (ECoG) confirmed the presence of face-selective neuronal populations...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2015.08.003
更新日期:2016-03-01 00:00:00
abstract::A number of previous studies have implicated regions in posterior auditory cortex (AC) in auditory-motor integration during speech production. Other studies, in turn, have shown that activation in AC and adjacent regions in the inferior parietal lobule (IPL) is strongly modulated during active listening and depends on...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2018.11.006
更新日期:2019-02-18 00:00:00
abstract::To test the idea that associated with stuttering is a cognitive difficulty related to the organization of sequences of responses, stutterers and fluent speakers were compared on a task that required the transcription to paper of rapidly presented letter sequences ranging in length from 3 to 10 letters. Compared to flu...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(87)90123-0
更新日期:1987-01-01 00:00:00
abstract::Greater amounts of physical activity (PA) and omega-3 fatty acids have both been independently associated with better cognitive performance. Because of the overlapping biological effects of omega-3 fatty acids and PA, fatty acid intake may modify the effects of PA on neurocognitive function. The present study tested t...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.04.018
更新日期:2014-07-01 00:00:00
abstract::Cognitive estimation is an important function in daily living. In early studies it was proposed that estimation deficits are associated with frontal lobe damage and executive dysfunctions. In this study, we assessed Alzheimer patients and patients with alcoholic Korsakoff's syndrome with a newly developed cognitive es...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(02)00183-5
更新日期:2003-01-01 00:00:00
abstract::Spatial relations between objects can be represented either categorically or coordinately. The metric, coordinate representation is associated with predominant right hemisphere activity, while the abstract, qualitative categorical representation is thought to be processed more in the left hemisphere [Kosslyn, S. M. (1...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2007.03.021
更新日期:2007-06-18 00:00:00
abstract::Previous research has shown that individuals with Parkinson's disease (PD) show preserved learning of tool-related motor skills, while retention was impaired after a three-week delay, possibly as a result of striatal dysfunction. The goal of the current study was to identify if shorter delays and more extensive practi...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.01.020
更新日期:2017-02-01 00:00:00
abstract::Neuroimaging and patient studies show that different areas of cortex respectively specialize for general and selective, or category-specific, semantic processing. Why are there both semantic hubs and category-specificity, and how come that they emerge in different cortical regions? Can the activation time-course of th...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.07.004
更新日期:2017-04-01 00:00:00
abstract::Recent findings suggest that constructed experience, the ability to envision future events, activates the same cortical network as recollection of past events. For example, damage to one key area, the hippocampus, impairs patients' ability to remember the past and to imagine novel experiences (Hassabis, Kumaran, Vann,...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.01.004
更新日期:2010-04-01 00:00:00
abstract::We have studied the configuration of the cortico-subcortical language networks within the right hemisphere (RH) in nine left-handers, being operated on while awake for a cerebral glioma. Intraoperatively, language was mapped using cortico-subcortical electrostimulation, to avoid permanent deficit. In frontal regions, ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2008.07.017
更新日期:2008-12-01 00:00:00
abstract::It has been shown that synchrony of neuronal oscillations plays a critical role in effective communication between functionally distinct brain areas involving motor-sensory integration. However, the patterns of cortico-cortical coupling and their relation to behavioural success are widely unknown. Here, we analysed ch...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.09.026
更新日期:2011-11-01 00:00:00
abstract::The effects of a 3-week computerised alertness training on chronic (>3 months) visuospatial hemineglect were investigated prospectively in seven patients by means of neuropsychological tests and functional magnetic resonance imaging (fMRI). Following the alertness training, the group showed improved alertness and a si...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2005.09.008
更新日期:2006-01-01 00:00:00
abstract::The vestibular system contributes to a wide range of functions, from postural and oculomotor reflexes to spatial representation and cognition. Vestibular signals are important to maintain an internal, updated representation of the body position and movement in space. However, it is not clear to what extent they are al...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.07.026
更新日期:2011-09-01 00:00:00