Asymptomatic coronary artery disease managed by myocardial revascularization: results at 5 years.

abstract：:The indications for biventricular versus left ventricular mechanical circulatory support as a bridge to cardiac transplantation are not well established. In this study, 27 potential heart transplant candidates who were in imminent risk of dying before donor heart procurement were implanted with Thoratec prosthetic ven...

journal_title：Circulation

authors： Farrar DJ,Hill JD,Gray LA Jr,Galbraith TA,Chow E,Hershon JJ

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Hemodynamic stability after Norwood palliation often requires manipulation of pulmonary vascular resistance to alter the pulmonary-to-systemic blood flow ratio (Qp:Qs). Qp:Qs is often estimated from arterial saturation (SaO2), a practice based on 2 untested assumptions: constant systemic arteriovenous O2 dif...

journal_title：Circulation

authors： Taeed R,Schwartz SM,Pearl JM,Raake JL,Beekman RH 3rd,Manning PB,Nelson DP

更新日期：2001-06-05 00:00:00

abstract：BACKGROUND:Patients with primary amyloidosis (AL type) have a poor prognosis, in part due to frequent cardiac involvement. Although intracardiac thrombus has been reported in anecdotal cases, neither its frequency nor its role in causing mortality is known. Furthermore, the clinical and echocardiographic variables that...

journal_title：Circulation

authors： Feng D,Edwards WD,Oh JK,Chandrasekaran K,Grogan M,Martinez MW,Syed IS,Hughes DA,Lust JA,Jaffe AS,Gertz MA,Klarich KW

更新日期：2007-11-20 00:00:00

abstract：BACKGROUND:Early risk assessment is important in patients with unstable coronary artery disease, ie, unstable angina or non-Q-wave myocardial infarction. Some previous small studies have indicated that patients with unstable angina and elevation of troponin T (tn-T) have worse short-term and long-term prognoses. In thi...

journal_title：Circulation

authors： Lindahl B,Venge P,Wallentin L

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The mechanism and treatment of diastolic heart failure are poorly understood. We compared the effects of an ACE inhibitor, an angiotensin receptor blocker (ARB), and their combination on diastolic heart failure in Dahl salt-sensitive (DS) rats. METHODS AND RESULTS:DS rats fed an 8% NaCl diet from 7 weeks of...

journal_title：Circulation

authors： Kim S,Yoshiyama M,Izumi Y,Kawano H,Kimoto M,Zhan Y,Iwao H

更新日期：2001-01-02 00:00:00

abstract：:The dominance of the coronary arterial system was determined angiographically in 75 adult patients with isolated aortic stenosis with or without insufficiency, 25 adult patients with pure aortic insufficiency, 51 adult patients with combined aortic stenosis and mitral valve disease, and 44 children with bicuspid aorti...

journal_title：Circulation

authors： Higgins CB,Wexler L

更新日期：1975-08-01 00:00:00

abstract：:A longitudinal study was made of 62 patients with dextro-transposition of the great arteries. The patients were managed with balloon atrial septostomy (BAS), palliative surgery if any operation was needed in the first year of life, and Mustard intra-atrial baffle repair after one year of age. Of the 47 patients with i...

journal_title：Circulation

authors： Gutgesell HP,McNamara DG

更新日期：1975-01-01 00:00:00

abstract：:The echocardiograms of 46 patients with aortic insufficiency which manifested typical high frequency vibrations of the anterior mitral valve leaflet were reviewed. All patients had overt clinical evidence of aortic insufficiency which was confirmed by angiography in 17 cases. In 17 cases (eight of whom underwent cat...

journal_title：Circulation

authors： Cope GD,Kisslo JA,Johnson ML,Myers S

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Mendelian randomization studies have highlighted that lipoprotein(a) [Lp(a)] was associated with calcific aortic valve disease (CAVD). Lp(a) transports oxidized phospholipids with a high content in lysophosphatidylcholine. Autotaxin (ATX) transforms lysophosphatidylcholine into lysophosphatidic acid. We hypo...

journal_title：Circulation

authors： Bouchareb R,Mahmut A,Nsaibia MJ,Boulanger MC,Dahou A,Lépine JL,Laflamme MH,Hadji F,Couture C,Trahan S,Pagé S,Bossé Y,Pibarot P,Scipione CA,Romagnuolo R,Koschinsky ML,Arsenault BJ,Marette A,Mathieu P

更新日期：2015-08-25 00:00:00

abstract：:Patency of the femoral artery of infants and children who previously had percutaneous arterial catheterization at a weight of less than 25 kg was studied angiographically. During the study period, 118 patients had repeat arterial catheterization. 48 from the opposite leg. Femoral artery occlusion was found in four pat...

journal_title：Circulation

authors： Hurwitz RA,Franken EA Jr,Girod DA,Smith JA,Smith WL

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Our objective was to investigate the association between hypertension and concurrent impairments in mobility, cognition, and mood; the role of brain white matter hyperintensities in mediating this association; and the impact of these impairments on disability and mortality in elderly hypertensive individuals...

journal_title：Circulation

authors： Hajjar I,Quach L,Yang F,Chaves PH,Newman AB,Mukamal K,Longstreth W Jr,Inzitari M,Lipsitz LA

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Older coronary patients are at high risk of cardiac disability. Exercise conditioning programs have been demonstrated to improve functional capacity, particularly in younger coronary patients. In this study, the effects of aerobic conditioning on submaximal and maximal indicators of exercise performance were...

journal_title：Circulation

authors： Ades PA,Waldmann ML,Poehlman ET,Gray P,Horton ED,Horton ES,LeWinter MM

更新日期：1993-08-01 00:00:00

abstract：:In patients treated with sulfinpyrazone, an apparent reduction in the incidence of sudden death and presumed ventricular fibrillation has been reported. Using an intact animal model without microcirculatory thrombosis, we studied the effects of sulfinpyrazone on ischemic myocardium in 58 anesthetized dogs divided into...

journal_title：Circulation

authors： Moschos CB,Escobinas AJ,Jorgensen OB Jr,Regan TJ

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Both a vascular endothelial cytochrome P450 (CYP450) product of arachidonic acid metabolism and the potassium ion (K(+)) have been identified as endothelium-derived hyperpolarizing factors (EDHFs) in animal vascular tissues. We studied the relative importance of EDHF, nitric oxide (NO), and prostacyclin (PGI...

journal_title：Circulation

authors： Coats P,Johnston F,MacDonald J,McMurray JJ,Hillier C

更新日期：2001-03-27 00:00:00

abstract：BACKGROUND:Optical mapping of cytosolic calcium transients in intact mammalian hearts is now possible using long-wavelength [Ca(2+)](i) indicators. We propose that beat-to-beat [Ca(2+)](i) transient alternans during ischemia may lead to spatial and temporal heterogeneity of calcium-activated membrane currents. METHODS...

journal_title：Circulation

authors： Qian YW,Clusin WT,Lin SF,Han J,Sung RJ

更新日期：2001-10-23 00:00:00

abstract：BACKGROUND:The late hemodynamic effects of preserving the papillary muscles during mitral valve replacement have not been evaluated. METHODS AND RESULTS:Sixteen patients who had chronic mitral regurgitation due to myxomatous degeneration were randomized to preservation (Pres group, n = 8) or no preservation (No Pres g...

journal_title：Circulation

authors： Komeda M,David TE,Rao V,Sun Z,Weisel RD,Burns RJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) is considered when respiratory failure (RF) persists despite increasing conventional mechanical ventilation (CMV). High-frequency jet ventilation (HFJV) can improve ventilation with comparable mean airway pressure (PAW) to that found on CMV. This study was undertake...

journal_title：Circulation

authors： Kocis KC,Meliones JN,Dekeon MK,Callow LB,Lupinetti FM,Bove EL

更新日期：1992-11-01 00:00:00

abstract：:An external cardiac pacemaker-monitor has been developed that provides safe, effective noninvasive ventricular stimulation that is well tolerated in conscious patients and allows clear recognition of electrocardiographic response. The noninvasive temporary pacemaker (NTP) has now been applied in 134 patients in five h...

journal_title：Circulation

authors： Zoll PM,Zoll RH,Falk RH,Clinton JE,Eitel DR,Antman EM

更新日期：1985-05-01 00:00:00

abstract：:To evaluate the potential advantages of thallium-201 (201T1) single-photon emission computerized tomography (SPECT) to assess myocardial infarct size in the experimental animal, six normal dogs and 14 dogs with 6 to 8 hr closed-chest coronary occlusion (eight left anterior descending and six left circumflex) were stud...

journal_title：Circulation

authors： Prigent F,Maddahi J,Garcia EV,Satoh Y,Van Train K,Berman DS

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:We investigated whether electrical stimulation (STIM) of efferent vagus nerves may suppress nuclear factor (NF)-kappaB activation and the inflammatory cascade in hemorrhagic (Hem) shock. METHODS AND RESULTS:Rats were subjected to bilateral cervical vagotomy (VGX) or sham surgical procedures. Hem shock was i...

journal_title：Circulation

authors： Guarini S,Altavilla D,Cainazzo MM,Giuliani D,Bigiani A,Marini H,Squadrito G,Minutoli L,Bertolini A,Marini R,Adamo EB,Venuti FS,Squadrito F

更新日期：2003-03-04 00:00:00

abstract：BACKGROUND:Endothelial dysfunction may contribute to the risk of premature atherosclerosis in patients with diabetes. Endothelin (ET-1) may be involved in this process by activating smooth muscle cell mitogenesis and leukocyte adhesion. We sought to assess the activity of endogenous ET-1 in a group of patients with typ...

journal_title：Circulation

authors： Cardillo C,Campia U,Bryant MB,Panza JA

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Activation of the sympathetic nervous system has important prognostic implications in chronic heart failure. Nonselective versus selective beta-adrenergic receptor antagonists may have differential effects on norepinephrine release from nerve terminals mediated by prejunctional beta(2)-adrenergic receptors. ...

journal_title：Circulation

authors： Azevedo ER,Kubo T,Mak S,Al-Hesayen A,Schofield A,Allan R,Kelly S,Newton GE,Floras JS,Parker JD

更新日期：2001-10-30 00:00:00

abstract：:Twelve healthy men were studied by M mode echocardiography during exercise to investigate the effect of afterload reduction on left ventricular function at maximal exertion. They performed two maximal exercise bicycle tests 4 hr apart while in the semisupine position and were given 20 mg nifedipine sublingually 30 min...

journal_title：Circulation

authors： Andersen K,Vik-Mo H

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Worldwide, diabetes mellitus and heart failure represent frequent comorbidities with high socioeconomic impact and steadily growing incidence, calling for a better understanding of how diabetic metabolism promotes cardiac dysfunction. Paradoxically, some glucose-lowering drugs have been shown to worsen heart...

journal_title：Circulation

authors： Kronlage M,Dewenter M,Grosso J,Fleming T,Oehl U,Lehmann LH,Falcão-Pires I,Leite-Moreira AF,Volk N,Gröne HJ,Müller OJ,Sickmann A,Katus HA,Backs J

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:Joint National Committee goal blood pressure for all adults was <140/<90 mm Hg or lower from 1984 to 2013. Adults aged ≥60 years (older) have mainly isolated systolic hypertension, with major trials attaining systolic blood pressure <150 but not <140 mm Hg. The main objective was to assess changes in hyperte...

journal_title：Circulation

authors： Egan BM,Li J,Shatat IF,Fuller JM,Sinopoli A

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:The future risk of myocardial infarction is commonly assessed using cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis severity. We assessed whether noncalcified low-attenuation plaque burden on coronary CT angiography (CCTA) might be a better predictor of the future risk ...

journal_title：Circulation

authors： Williams MC,Kwiecinski J,Doris M,McElhinney P,D'Souza MS,Cadet S,Adamson PD,Moss AJ,Alam S,Hunter A,Shah ASV,Mills NL,Pawade T,Wang C,Weir McCall J,Bonnici-Mallia M,Murrills C,Roditi G,van Beek EJR,Shaw LJ,Nicol E

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Short-term (<30 day) mortality after Q-wave myocardial infarction (MI) has declined over the decades, but it is unclear if rates of long-term sequelae after Q-wave MI have improved. METHODS AND RESULTS:In 546 Framingham Heart Study subjects (388 men with a mean age of 60 years; 158 women with a mean age of ...

journal_title：Circulation

authors： Guidry UC,Evans JC,Larson MG,Wilson PW,Murabito JM,Levy D

更新日期：1999-11-16 00:00:00

abstract：BACKGROUND:Atrial dysrhythmia patients have exaggerated intra-atrial conduction delays and prolonged relative refractoriness in response to atrial premature depolarizations (APDs). Furthermore, atrial fibrillation (AF) is more readily inducible by APDs from the high right atrium (HRA) than the coronary sinus (CS). In t...

journal_title：Circulation

authors： Papageorgiou P,Monahan K,Boyle NG,Seifert MJ,Beswick P,Zebede J,Epstein LM,Josephson ME

更新日期：1996-08-01 00:00:00

abstract：:Reactive oxygen species such as the superoxide anion (.O2-) have recently been implicated as important agents involved in causing cell death in the setting of myocardial ischemia and reperfusion. When superoxide anion is involved in ischemic injury the administration of superoxide dismutase (SOD) may limit infarct siz...

journal_title：Circulation

authors： Uraizee A,Reimer KA,Murry CE,Jennings RB

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:Cardiac allograft arteriosclerosis is a complex process of alloimmune response, chronic inflammation, and smooth muscle cell proliferation that includes cross talk between cytokines and growth factors. METHODS AND RESULTS:Our results in rat cardiac allografts established alloimmune response as an alternativ...

journal_title：Circulation

authors： Lemström KB,Krebs R,Nykänen AI,Tikkanen JM,Sihvola RK,Aaltola EM,Häyry PJ,Wood J,Alitalo K,Ylä-Herttuala S,Koskinen PK

更新日期：2002-05-28 00:00:00