Effects of postnatal dexamethasone exposure on the developmental outcome of premature infants.

Abstract:

:Extremely low birth weight premature infants are at risk for poor neurodevelopmental outcome. Postnatal dexamethasone has often been used in premature infants to prevent or treat bronchopulmonary dysplasia, and this drug is thought by some to affect neurodevelopmental outcome. We retrospectively examined the effect of this steroid on early neurodevelopment. Dexamethasone exposure was associated with an adverse outcome and was a stronger predictor of outcome than other accepted risk factors. If used, dexamethasone should be used in these high-risk infants for as short a period as possible.

journal_name

J Child Neurol

authors

Needelman H,Evans M,Roberts H,Sweney M,Bodensteiner JB

doi

10.1177/0883073807309232

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

421-4

issue

4

eissn

0883-0738

issn

1708-8283

pii

0883073807309232

journal_volume

23

pub_type

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