Agammaglobulinemia and Staphylococcus aureus botryomycosis in a cohort of related sentinel Swiss Webster mice.

Abstract:

:Sentinel mouse seroconversion to infectious agents is critical for laboratory animal facility disease monitoring. We report spontaneous emergence of non-sex-linked agammaglobulinemia with B-cell deficiency and cutaneous Staphylococcus aureus granulomatosis (botryomycosis) in a cohort of related Swiss Webster sentinel mice. Our experience reinforces the importance of immunocompetency validation in surveillance programs.

journal_name

J Clin Microbiol

authors

Bridgeford EC,Fox JG,Nambiar PR,Rogers AB

doi

10.1128/JCM.01875-07

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

1881-4

issue

5

eissn

0095-1137

issn

1098-660X

pii

JCM.01875-07

journal_volume

46

pub_type

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