Abstract:
:Patients with malignant obstructive airway lesions often present with total or segmental atelectasis of lung. In spite of prompt initiation of palliative external radiation alone, some patients were unable to complete the planned course of radiation therapy. Since May 1983, 17 patients with malignant obstructive endobronchial lesions have been treated by endoscopic Nd:YAG laser vaporization of the tumor. One to seven days later, fractionated external radiation therapy was initiated. Endoscopic use of the laser was repeated as needed during the course of treatment. Fifteen out of 17 patients successfully completed the planned course of therapy. The improved performance status was sustained in 13 of 15 patients for 2-13 months. A control group was selected from among patients with similarly located lesions who underwent external radiation treatment only prior to the availability of the Nd:YAG laser therapy. One patient developed radiation pneumonitis six weeks after completion of a second course of external radiation, another patient developed bronchopleural fistula after laser treatment which healed following closed chest tube drainage. The others had longer palliation of symptoms and improved quality of life. The results indicate that relief of airway obstruction by use of the Nd:YAG laser improved the patients' ability to tolerate subsequent external radiation treatment.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Jain PR,Dedhia HV,Lapp NL,Thompson AB,Frich JC Jrdoi
10.1002/lsm.1900050107subject
Has Abstractpub_date
1985-01-01 00:00:00pages
47-53issue
1eissn
0196-8092issn
1096-9101journal_volume
5pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:Very few treatments for striae are based on prospective randomized trials. The objective of this study was to assess the efficacy of bipolar fractional radiofrequency and bipolar radiofrequency potentiated with infrared light, alone or combined, for treating abdominal stretch marks. STUDY DESI...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/lsm.22458
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Inhibition of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti-inflammatory effects have been reported in clinical fields for specific wavelength irradiation d...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20533
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Despite laser applications targetted toward tonsillar tissue, there has been no characterization of underlying optical and thermal events during laser irradiation of tonsillar tissue. STUDY DESIGN/MATERIALS AND METHODS:The optical properties of canine and human tonsils were determined at 805 n...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1055
更新日期:2001-01-01 00:00:00
abstract::Low power laser irradiation has been reported to cause biological effects due to the photochemical and/or photophysical action of the radiation. This study determined quantitatively if transcutaneous low power laser irradiation can affect the regeneration of the rat facial nerve. The facial nerve was crushed unilatera...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900130113
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:High-power laser has recently become a physical stimulus for bone regeneration. Little is known about how high-power laser irradiation affects osteoblast differentiation. This study investigated osteoblast responses to high-power laser and combined irradiation with BMP-2 treatment. STUDY DESIG...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20870
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We evaluated the potential of combining laser excision with laser interstitial hyperthermia in order to improve the quality of life of patients with 3rd or 4th stage malignant head and neck tumours. STUDY DESIGN/MATERIALS AND METHODS:To evaluate the quality of life, we used the 4th version of...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10253
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:For Asian skin, recent "non-ablative" skin rejuvenation techniques have become the focus of attention for darker complected patients. In our earlier research, we have shown that intense pulsed light (IPL) technology can be applied to Asian skin with a high degree of safety and efficacy. In thi...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10036
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Whether light emitting diode (LED) irradiation has effects on "beta-amyloid (A beta) induced apoptosis," a leading hypothesis of the cause of Alzheimer's disease (AD), or not? STUDY DESIGN/MATERIALS AND METHODS:Monolayer cell cultures of PC12 were subjected to A beta or/and LED irradiation at...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10216
更新日期:2003-01-01 00:00:00
abstract::Assessments of non-surgical office-based aesthetic treatments' efficacy including lasers are mostly based on subjective evaluation of clinical photography. Accumulating evidence suggest that non-invasive skin imaging such as optical coherence tomography (OCT) can be effectively used to assess not only the skin surface...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,评审
doi:10.1002/lsm.23219
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Primary blast injury is produced by shock waves. Blast injuries to lungs are extremely critical threats to survival, but their etiology is largely undefined. The majority of animal models for these injuries use explosive or complex experimental settings, limiting the laboratory study of blast ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20899
更新日期:2010-04-01 00:00:00
abstract::Current laser dentistry since our initial studies in 1964 is reviewed. Three areas are considered: routine dental office practice, tooth restoration, and oral surgery. For tooth restoration and oral surgery, CO2 and neodymium:YAG lasers are used and lasers are used in photodynamic therapy for oral cancer. Dental offic...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900060616
更新日期:1987-01-01 00:00:00
abstract::Histological investigation of the dog's myocardium performed 7 and 25 days after irradiation with different doses of Nd-YAG laser show that the damage zone has the shape of a hollow sphere with minor changes in cardiomyocytes in the central part of the sphere. The small blood vessels in the irradiated zone remained un...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900050506
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Low-intensity laser irradiation is claimed to enhance wound healing. Healing after myocardial infarction results in ventricular enlargement and wall thinning. If laser treatment accelerated cardiac healing, we speculated that ventricular remodeling would be attenuated. STUDY DESIGN/MATERIALS A...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/1096-9101(2000)27:1<29::aid-lsm4>3.0.co;2-
更新日期:2000-01-01 00:00:00
abstract::Photochemical internalization (PCI) is a method for intracellular delivery of hydrophilic macromolecular drugs with intracellular targets as well as other drugs with limited ability to penetrate cellular membranes. Such drugs enter cells by means of endocytosis and are to a large extent degraded by hydrolytic enzymes ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,评审
doi:10.1002/lsm.21084
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Facial teleangectasias can be a relevant cosmetic problem, which the patient usually hides with a thick layer of makeup. This study will describe the response on these vascular lesions using the intense pulsed light (IPL) source. METHODS:Five hundred eighteen consecutive patients were treated...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20187
更新日期:2005-07-01 00:00:00
abstract::This is the first report on the use of endoscopic argon photoirradiation to treat patients with low-grade ureteral tumors involving the distal ureter. Using a rigid ureteropyeloscope, a 300 mu or 600 mu quartz fiber, and 5 watts (W) of power in a continuous-wave mode, the lesions were ablated without complication. Pat...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900120506
更新日期:1992-01-01 00:00:00
abstract::New instruments to facilitate laser operations are presented. These devices are based on the Kocher bronchocoele sound and are useful as dissecting tools and optical backstops to prevent iatrogenic injury. ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900100613
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Transient optical nerve stimulation is a promising new non-contact, spatially precise, artifact-free neural excitation technique useful in research and clinical settings. This study evaluates safety of this pulsed infrared laser technique by histopathologic examination of stimulated peripheral ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20522
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The holmium:YAG (Ho:YAG) laser can be used not only for soft tissue but also for hard tissue such as urinary calculi. The objective of this study was to assess the usefulness of the Ho:YAG laser for endoscopic lithotripsy in patients with urinary tract stone. STUDY DESIGN/MATERIASL AND METHODS:...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/(sici)1096-9101(1999)25:5<389::aid-lsm4>3.
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To investigate the morphology of cementum and root dentin after Er:YAG laser irradiation with and without water coolant, compared to that after CO(2) laser irradiation and an untreated surface. STUDY DESIGN/MATERIALS AND METHODS:Ten extracted healthy human teeth were used. Er:YAG and CO(2) la...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10074
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In Holmium laser lithotripsy, usually, the surgeon is guided by a visible beam superimposing the infrared (IR) treatment radiation. It has been shown that a green aiming beam excites stone autofluorescence. This fluorescence signal can be used for calculi detection to check the correct fiber p...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.23154
更新日期:2020-06-01 00:00:00
abstract::CO2, Nd:YAG, and argon lasers have been used for 5 years for experimental and clinical procedures at the National Cancer Institute of Milan under the auspices of the National Research Council. Experimental data regarding tumor cell spread through lymphatic and hematic channels and cell viability in the fumes after CO2...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900020409
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to examine the influence of implant bed preparation, using either Er:YAG laser ablation, piezoelectric surgery or drill osteotomy, on osseointegration of titanium dental implants after 4, 6, and 8 weeks. MATERIAL AND METHODS:A total of 108 implants (Camlog) were plac...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20944
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To further understand the precise process of the tumor cell degeneration after photodynamic therapy (PDT), laser hyperthermic therapy (LH), and combined treatments using an Nd:YAG laser. It is important to examine initial morphological alteration of tumor cells after these treatments. STUDY DE...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900160308
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To test whether autofluorescence spectroscopy can be used for the diagnosis of oral neoplasia in a high-risk population, we characterized the in vivo autofluorescence spectra from oral submucous fibrosis (OSF) lesions and oral premalignant and malignant lesions in both OSF and non-OSF patients...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10180
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Endoscopic third ventriculostomy is used to treat hydrocephalus. Different laser wavelengths have been proposed for laser-assisted endoscopic third ventriculostomies over the last decades. The aim of this study was to evaluate Thulium laser endoscopic third ventriculostomy heat penetration in t...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22779
更新日期:2017-12-07 00:00:00
abstract::This paper describes the use of a pulsed argon laser to perform iridotomies in 87 patients. Diagnosis include: primary angle closure glaucoma, narrow angle in the fellow eye of patients with primary angle glaucoma, pupillary block, and after incomplete surgical iridectomies. Laser iridotomy was achieved in 79% of pati...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900010205
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Efficacy of topical anesthetics can be enhanced by pretreatment of the skin with ablative fractional lasers. However, little is known about the role of parameters such as laser modality and laser density settings in this technique. Aims of this study were to compare the efficacy of pretreatmen...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.22936
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Noninvasive bipolar and monopolar radiofrequency (RF) deep dermal heating devices have previously been described. A novel minimally invasive RF device employing a bipolar microneedle electrode system is introduced and its resultant thermal effects on human skin in vivo were characterized for t...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20687
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Platelet-rich plasma (PRP) which contains large amounts of growth factors has been tried to enhance therapeutic efficacy of laser treatment for acne scar with unknown underlying mechanism. OBJECTIVES:The present study was conducted to investigate the molecular mechanism of increased clinical efficacy of PRP...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.22776
更新日期:2018-04-01 00:00:00