Abstract:
:This study determined whether a rise in tonic secretion of LH occurred before long day-induced precocious puberty of the female ferret. Twenty immature females were assigned to 1 of 2 photoperiods at 15 weeks of age. Ten ferrets were placed in a long day, stimulatory photoperiod (16 h of light, 8 h of darkness) to induce sexual maturation, and 10 remained in the nonstimulatory photoperiod (8 h of light, 16 h of darkness) for the duration of the study. Intensive blood sampling regimens (every 10 min for 8 h) were conducted at selected times after the onset of long days to permit definition of detailed secretory patterns of plasma LH. Females in each photoperiod were sampled from chronic jugular venous catheters approximately twice weekly until puberty was evident in females housed in long days. The end point for determination of the pubertal onset of adult ovarian function was the appearance of estrogen-sensitive vulvar edema. Results show a marked increase in frequency of episodes of LH secretion per 8-h interval in females undergoing sexual maturation. No such change in frequency occurred in unstimulated females housed continuously in short days, nor did the short day females exhibit vulvar edema. Further, the increment in LH secretion occurred before either vulvar edema or a significant increase in plasma estradiol levels was observed. Therefore, the rise in LH secretion that occurs after several weeks of exposure to a long day photoperiod may well be an important drive to maturational changes in ovarian function.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Ryan KD,Robinson SLdoi
10.1210/endo-116-5-2013subject
Has Abstractpub_date
1985-05-01 00:00:00pages
2013-8issue
5eissn
0013-7227issn
1945-7170journal_volume
116pub_type
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