Abstract:
:We have investigated the possibility that IGF-1 may play a role in the regulation of antler development. Plasma IGF-1 concentrations were measured throughout the first period of development of the pedicle and first antler of red deer (Cervus elaphus) to determine whether a relationship existed between growth of antler cartilage (velvet antler) and IGF-1. We report that plasma levels of IGF-1 are significantly elevated during the velvet antler growing phase relative to the other phases of pedicle and first antler development and a strong positive correlation exists between antler growth rate and circulating concentrations of IGF-1. As IGF-1 has been demonstrated to influence cartilage growth, we suggest that IGF-1 is a candidate as an antler stimulating hormone.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Suttie JM,Gluckman PD,Butler JH,Fennessy PF,Corson ID,Laas FJdoi
10.1210/endo-116-2-846subject
Has Abstractpub_date
1985-02-01 00:00:00pages
846-8issue
2eissn
0013-7227issn
1945-7170journal_volume
116pub_type
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