Abstract:
:Diabetes mellitus is a metabolic disorder characterized by elevated fasting and postprandial blood glucose levels. It is also accompanied with a variety of multisystem complications that include the blood vessels, nervous system, eyes, kidneys, and skin. The main cutaneous complications are discussed.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Oumeish OYdoi
10.1016/j.clindermatol.2007.10.015subject
Has Abstractpub_date
2008-05-01 00:00:00pages
235-42issue
3eissn
0738-081Xissn
1879-1131pii
S0738-081X(07)00238-6journal_volume
26pub_type
杂志文章,评审abstract::In 2002, new guidelines for interactions with the pharmaceutical industry and physicians were published as an official code of conduct. Adherence to the guidelines was voluntary, and there were no provisions for discipline to companies who did not subscribe to the code or who subscribed but did not comply. Many of the...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.02.005
更新日期:2009-07-01 00:00:00
abstract::Variations in pain perception have long been studied in the medical literature, especially for women in regards to their menstrual cycle. Anecdotally, women can be more sensitive to painful stimuli from cosmetic procedures during their menses; however, no studies have thoroughly examined variations in pain perception ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.10.011
更新日期:2019-01-01 00:00:00
abstract::Dermatologic manifestations of parathyroid-related disorders, although rare in sporadic cases, are not uncommon in familial syndromes. Patients with familial hyperparathyroidism have several types of skin lesions. In multiple endocrine neoplasia 1, patients commonly have angiofibromas (85%) and collagenomas (70%), les...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2006.04.003
更新日期:2006-07-01 00:00:00
abstract::Actinic keratoses (AKs) represent the earliest stage in the development of squamous cell carcinoma (SCC) and represent important biomarkers for individuals at risk for development of invasive SCC. Based on clinical morphology, AK can be subdivided into three different grades, which correspond to specific dermatoscopic...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2013.05.028
更新日期:2014-01-01 00:00:00
abstract::Atopic dermatitis (AD), the most prevalent inflammatory skin disease, is characterized by robust T-cell activation. The disease has several subtypes, all having a common T helper type 2 (Th2)/Th22 polarization, but it also displays differential immune skewing, such as increased Th17/interleukin 23 skewing in the skin ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2017.03.012
更新日期:2017-01-01 00:00:00
abstract::Different physical treatments may be used in acne therapy. The main indications are for treating retentional lesions (open and comedones), inflamed lesions, and scars. ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2004.03.017
更新日期:2004-09-01 00:00:00
abstract::Psoriasis is a chronic, inflammatory and hyperproliferative skin disease with a genetic basis. While epidermal hyperplasia and altered keratinocyte differentiation are prominent features, considerable evidence indicates that psoriasis is immunologically mediated. Recently, the identification of HLA-Cw6 as the disease ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2007.08.007
更新日期:2007-11-01 00:00:00
abstract::Patient education programs are beneficial in the treatment of chronic diseases. In Germany, France, and other countries worldwide, educating children, adolescents, and adults plus the parents of children with atopic dermatitis (AD) leads to better coping with the skin disease, as well as to a reduction in the severity...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2018.05.006
更新日期:2018-01-01 00:00:00
abstract::Psychocutaneous morbidity is commonly found in dermatologic practice. Patients generally refuse referral to psychiatry, and dermatologists cannot always provide psychotherapeutic support. By establishing an alliance with these patients and with working knowledge of the common psychotherapeutic agents used in dermatolo...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2011.11.013
更新日期:2013-01-01 00:00:00
abstract::Many studies have investigated cutaneous reactions to antitumor drugs and found them to be quite numerous. We describe drug eruptions that may be associated with different therapies by class: antimetabolite chemotherapeutics, genotoxic agents, spindle inhibitors, signal transduction inhibitors, and immunotherapies. Me...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.10.006
更新日期:2020-01-01 00:00:00
abstract::Most neoplasms of the nail apparatus have different clinical appearances, courses, and biological behaviors as compared with similar tumors located elsewhere on the skin. Some of these tumors are unique to the nail, such as onychomatricoma. As a general rule, benign lesions respect the general architecture of the nail...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2013.06.014
更新日期:2013-09-01 00:00:00
abstract::Adjuvant immunosuppressive drugs are widely used to minimize corticosteroid-related adverse effects in the short-term and long-term management of cautoimmune bullous diseases. In bullous pemphigoid and pemphigus vulgaris, azathioprine and mycophenolate mofetil seem to be equally effective when used in combination with...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2011.03.013
更新日期:2012-01-01 00:00:00
abstract::Since the introduction of botulinum toxin (BTX) as a therapeutic tool in the 1970s, the number of uses for this substance has increased exponentially. BTX's mechanism of action involves degrading the SNARE proteins blockading the release of acetylcholine into the neuromuscular junction. In many body systems, decrease ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2003.12.030
更新日期:2004-01-01 00:00:00
abstract::A new or changing melanocytic nevus in a child or adolescent often leads to concern in parents and physicians. To avoid undue alarm and unnecessary procedures, dermatologists should be aware of the natural history and clinical spectrum of nevi in pediatric patients, as well as findings that are potentially worrisome i...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2014.12.015
更新日期:2015-05-01 00:00:00
abstract::The elderly population is growing, lifespans are increasing, and a greater emphasis on geriatric care is being implemented in hospital systems. With a higher percentage of the population living longer, hair and nail diseases associated with the advanced stages of life are becoming more prevalent. Common hair diseases ...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2017.10.007
更新日期:2018-01-01 00:00:00
abstract::There is an almost innate urge in human beings to represent reality in a visual form. From rock art in the Paleolithic to images of galaxies, the quotidian and the extraordinary have been visually represented through the ages. Medical and scientific disciplines are no exception. Accurate representation of the human bo...
journal_title:Clinics in dermatology
pub_type: 历史文章,杂志文章
doi:10.1016/j.clindermatol.2018.09.008
更新日期:2019-01-01 00:00:00
abstract::As new laser devices continue to emerge, it becomes increasingly important for the clinical dermatologist to understand the basic principles behind their operation. A fundamental understanding of how lasers interact with tissue will enable the physician to choose the most appropriate laser for a given clinical situati...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2005.10.019
更新日期:2006-01-01 00:00:00
abstract::Alopecia is a skin condition of great social and psychologic impact. Primary alopecia originates from the hair follicles and usually does not have systemic manifestations; however, secondary alopecia can affect the hair follicles in the setting of systemic diseases, medications, and external trauma. Connective tissue ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.07.026
更新日期:2019-01-01 00:00:00
abstract::The Accreditation Council for Graduate Medical Education and the Royal College of Physicians and Surgeons of Canada both require the teaching and demonstration of general competencies, which include professionalism and ethics as a condition of training program accreditation and specialty certification, respectively. R...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.02.015
更新日期:2009-07-01 00:00:00
abstract::A red swollen face can be a skin sign of a potentially life-threatening condition. We present in detail the main clinical presentations, diagnostic tests, and management of some of the most severe conditions that can frequently present as a red and swollen face: acute or recurrent angioedema, mast cell-driven or brady...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.10.017
更新日期:2020-01-01 00:00:00
abstract::Human papillomaviruses (HPV) are clearly responsible for the induction of genital lesions like condylomata acuminata, bowenoid papules, and flat condylomas. Moreover, the DNA of particular virus types (HPV 16 and 18) is found in a substantial number of invasively growing squamous cell carcinomas of the genital tract, ...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/0738-081x(85)90056-2
更新日期:1985-10-01 00:00:00
abstract::Paraviral eruptions, such as the papular-purpuric gloves and socks syndrome or eruptive pseudoangiomatosis, share the following features that distinguish them from a classic viral eruption: they are highly recognizable; the eruption usually lasts a few weeks; many different viruses and sometimes other agents can trigg...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2020.06.005
更新日期:2020-01-01 00:00:00
abstract::The most extensive investigations of treatment of New World cutaneous leishmaniasis have been performed against L. panamensis disease in Colombia, and the relative value of regimens shown there may be instructive for disease from other areas. In Colombia, a 90-95% cure rate was achieved with three different drug regim...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/0738-081x(96)00048-x
更新日期:1996-09-01 00:00:00
abstract::More than 127 loci are actually known to affect pigmentation in mouse when they are mutated. From embryogenesis to transfer of melanin to the keratinocytes or melanocytes survival, any defect is able to alter the pigmentation process. Many gene mutations are now described, but the function of their product protein and...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2004.09.013
更新日期:2005-01-01 00:00:00
abstract::From ancient times, light has played a significant role in the treatment of diseases. The modern discoveries (eg, ultraviolet radiation) and modern inventions (eg, the electric generator or the electric lightbulb), as well as balneologic experiences of the treatment with sunlight, contributed to the transition from he...
journal_title:Clinics in dermatology
pub_type: 历史文章,杂志文章
doi:10.1016/j.clindermatol.2016.05.002
更新日期:2016-09-01 00:00:00
abstract::The tongue is a complex organ involved in speech and expression as well as in gustation, mastication, and deglutition. The oral cavity, along with the tongue, are sites of neoplasms, reactive processes, and infections, and may be a harbinger of systemic diseases. This review includes both common and rare diseases that...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2016.02.018
更新日期:2016-07-01 00:00:00
abstract::Human epidermis consists of a stratified epithelium mainly composed of keratinocytes and relies on a stem cell compartment to undergo constant regeneration. Genetic mutations affecting the capacity of basal keratinocytes to adhere firmly to the epidermal basement membrane lead to severe, and very often lethal, blister...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2004.07.017
更新日期:2005-07-01 00:00:00
abstract::Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the under...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2016.02.004
更新日期:2016-05-01 00:00:00
abstract::The relationship between pregnancy and diseases of the elastic fibers, such as pseudoxanthoma elasticum, cutis laxa, and anetoderma, is discussed in this article. Dermatologists and other physicians must be aware that these problems may be present in pregnant women and must also know how to counsel those who suffer fr...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2005.10.005
更新日期:2006-03-01 00:00:00
abstract::The deeply rooted fascination with beauty penetrates society worldwide. The indulgence to look and feel beautiful pervades all ages, genders, and nationalities, with research conferring a remarkable tendency to agree on measures of attractiveness among these disparate groups. Research has found that beautiful people d...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2016.04.006
更新日期:2016-01-01 00:00:00