Clear cell adenocarcinoma arising in endometriosis of a previous episiotomy site.

Abstract:

BACKGROUND:Malignant transformation of endometriosis in an episiotomy site is rare. CASE:A 42-year-old woman presented with a palpable mass, 2.5 cm in size, just inside the posterior commissure of the vagina, at the site of a previous episiotomy for a vaginal delivery. Three years previously, an endometriotic cyst had been excised at the same site, and the patient had been treated with a gonadotropin-releasing hormone analogue for 6 months. Biopsy revealed a clear cell adenocarcinoma arising in endometriosis. The patient underwent radical surgery alone without adjuvant therapy. At 10-month follow-up, there was no evidence of recurrence. CONCLUSION:Patients who experience a recurrence of extragonadal endometriosis after prior therapy should be monitored carefully for malignant degeneration.

journal_name

Obstet Gynecol

authors

Kwon YS,Nam JH,Choi G

doi

10.1097/AOG.0b013e318179475b

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

475-7

issue

2 Pt 2

eissn

0029-7844

issn

1873-233X

pii

112/2/475

journal_volume

112

pub_type

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