Testosterone-producing solitary ovarian cyst with luteinized stromal-cell hyperplasia.

Abstract:

BACKGROUND:Hormone production is a characteristic associated with the presence of solid tumors in the ovary. We present a case of a solitary ovarian cyst producing large amounts of testosterone and presenting with rapid onset of hirsutism. CASE:A woman presented approximately 6 months postpartum with irregular menses and rapid onset of hirsutism. Laboratory and radiologic evaluation indicated an ovarian cyst as the source. On removal, the cyst was found to have high amounts of testosterone in its fluid and the surrounding stroma had nests of luteinized cells. CONCLUSION:The chronic anovulation in the postpartum period may have prolonged the lifespan of the luteinized stromal cells, resulting in high levels of circulating testosterone and causing rapid progression of hirsutism.

journal_name

Obstet Gynecol

authors

Goudas VT,Wasty F,Pardanani B,Ying YK

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

870-2

issue

5 Pt 2

eissn

0029-7844

issn

1873-233X

journal_volume

87

pub_type

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