Viral pathogens in acute exacerbations of chronic obstructive pulmonary disease.

Abstract:

:The objective of this study is to determine the prevalence of respiratory syncytial virus (RSV) and other viral respiratory pathogens in emergency department (ED) patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD patients presenting to the ED with <10 days of AECOPD symptoms were eligible. We used PCR to test nasal swabs for common viral respiratory pathogens. We completed viral studies on 76 patients from two EDs. Patients had a mean age of 72 years, and were 68% male, 99% white, and 29% current smokers. Influenza vaccination was reported by 87%. Viruses were detected in 19 of 76 patients (25%). These included RSV A (2) and B (4); parainfluenza 1 (1), 2 (0), and 3 (2); influenza A (3) and B (0); rhinovirus (4); and human metapneumovirus (3). A putative viral etiology was identified in 25% of AECOPD presenting for emergency care, of which approximately one-third were RSV-related.

journal_name

Intern Emerg Med

authors

Camargo CA Jr,Ginde AA,Clark S,Cartwright CP,Falsey AR,Niewoehner DE

doi

10.1007/s11739-008-0197-0

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

355-9

issue

4

eissn

1828-0447

issn

1970-9366

journal_volume

3

pub_type

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