Abstract:
:Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in December 2019. COVID-19 is caused by the Betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses angiotensin-converting enzyme 2, which is highly expressed in the human lower respiratory tract but also in other tissues, as the cellular entry receptor. Thus, COVID-19 mainly affects the respiratory system but can cause damage to other body systems, including the cardiovascular, gastrointestinal, hepatobiliary, renal, and central nervous systems. We review the pathogenesis and clinical manifestations of the infection, focusing on our current understanding of the disease mechanisms and their translation to clinical outcomes, as well as adverse effects on different body systems. We also discuss the epidemiology pathogenesis, clinical, and multi-organ consequences, and highlight some of the research gaps regarding COVID-19.
journal_name
Intern Emerg Medjournal_title
Internal and emergency medicineauthors
Krishnan A,Hamilton JP,Alqahtani SA,A Woreta Tdoi
10.1007/s11739-020-02616-5subject
Has Abstractpub_date
2021-01-16 00:00:00eissn
1828-0447issn
1970-9366pii
10.1007/s11739-020-02616-5pub_type
杂志文章,评审abstract::Genetic and acquired motor-neuron-disorders (MNDs) may undergo acute deterioration resulting in various emergency situations. This literature review aims at summarising and discussing current knowledge about emergencies in MNDs. Emergencies that have been reported in MND patients include: respiratory, bulbar, cardiac,...
journal_title:Internal and emergency medicine
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-008-0130-6
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journal_title:Internal and emergency medicine
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doi:10.1007/s11739-017-1691-z
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11739-018-1921-z
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doi:10.1007/s11739-018-1994-8
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pub_type: 杂志文章,评审
doi:10.1007/s11739-019-02252-8
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-016-1509-4
更新日期:2017-10-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,多中心研究
doi:10.1007/s11739-013-1006-y
更新日期:2014-09-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-015-1272-y
更新日期:2016-04-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02379-z
更新日期:2020-08-01 00:00:00
abstract::Assessing the effects of an antimicrobial stewardship program (ASP) implemented in a 78-bed Internal Medicine ward of an Italian mid-sized acute care hospital of 296 beds (26,820 bed days/year in 2015 and 26,653 in 2016). The ASP, implemented in May 2016, included: (a) formulation and dissemination of local guidelines...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-018-1916-9
更新日期:2018-12-01 00:00:00
abstract::Nowadays, amiodarone is the most commonly used antidysrhythmic drug in clinical practice. It is highly effective in the management of recurrent ventricular dysrhythmias, paroxysmal supraventricular dysrhythmias, including atrial fibrillation and flutter, and in the maintenance of sinus rhythm after electrical cardiove...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-014-1140-1
更新日期:2014-12-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-010-0492-4
更新日期:2011-08-01 00:00:00
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doi:10.1007/s11739-016-1519-2
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pub_type: 杂志文章,评审
doi:10.1007/s11739-010-0362-0
更新日期:2010-04-01 00:00:00
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abstract::Intracranial bruits (ICB) are faint, high-pitched, and mostly heard on the orbit in the systolic phase of the cardiovascular cycle. This report discusses a case of Listeria monocytogenes meningitis in a 17-month-old male patient in whom ICB were auscultated. ICB is thought to be caused by compression of blood vessels ...
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,已发布勘误
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更新日期:2020-06-01 00:00:00
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