Pharmacology and therapeutic use of low-dose dopamine.

abstract：:Hypertension and diabetes appear to increase coronary heart disease risk in part by causing an abnormality in lipid metabolism. Most affected are patients with familial dyslipidemic hypertension (FDH) and noninsulin-dependent diabetes mellitus (NIDDM). The lipid disorders most often encountered in these patients are i...

journal_title：Pharmacotherapy

authors： McKenney JM

更新日期：1993-07-01 00:00:00

abstract：:To determine the extent of hospital-based clinical pharmacy services in 1995, we surveyed 1109 United States acute care, general, medical-surgical, and pediatric hospitals with 50 or more licensed beds. Fifteen clinical pharmacy services were assessed to determine pharmacists' specific patient care responsibilities. T...

journal_title：Pharmacotherapy

authors： Raehl CL,Bond CA,Pitterle ME

更新日期：1998-03-01 00:00:00

abstract：:Recent evidence suggests that periodontal disease may predispose to atherosclerotic cardiovascular disease. Data support mechanisms of host-derived local and systemic proinflammatory responses similar to atherosclerosis, consisting of monocytic-derived cytokines and other inflammatory mediators, which are induced by p...

journal_title：Pharmacotherapy

authors： Chong PH,Kezele B

更新日期：2000-07-01 00:00:00

abstract：:Antiretroviral therapy has significantly improved the typical course of human immunodeficiency virus (HIV) infection in industrialized nations, and life expectancies associated with the infection have increased. However, infection rates have generally remained unchanged, with increases noted among certain subpopulatio...

journal_title：Pharmacotherapy

authors： Romanelli F,Murphy B

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To compare changes in United States pharmacy practice faculty demographics from 1995-2001 and to discuss the implications for junior faculty development. METHODS:Demographic data were extracted from the American Association of Colleges of Pharmacy institutional research system for academic years 1995-1996 an...

journal_title：Pharmacotherapy

authors： Raehl CL

更新日期：2002-04-01 00:00:00

abstract：:Data obtained from 23 critically ill patients treated with intravenous ciprofloxacin in two clinical trials were used to validate prospectively a previously developed maximum a posteriori (MAP)-Bayesian estimator and optimal plasma-sampling strategy (OSS). Dosages ranged from 200 mg every 12 hours to 400 mg every 8 ho...

journal_title：Pharmacotherapy

authors： Amsden GW,Ballow CH

更新日期：1996-09-01 00:00:00

abstract：:Abstract Outbreaks of extensively drug-resistant tuberculosis (XDR-TB) in developing countries and recent headlines of an American traveling with a resistant variant of tuberculosis have brought XDR-TB into the spotlight. The World Health Organization and the United States Centers for Disease Control and Prevention ha...

journal_title：Pharmacotherapy

authors： Mitrzyk BM

更新日期：2008-10-01 00:00:00

abstract：:We compared total costs and adherence to the regimen of older versus newer angiotensin-converting enzyme (ACE) inhibitors for the treatment of elderly patients with hypertension. A computer search using the data base of a health care insurer identified 6176 subjects age 65 years or older who had ICD-9 coding for hyper...

journal_title：Pharmacotherapy

authors： Small RE,Freeman-Arnold SB,Goode JV,Pyles MA

更新日期：1997-09-01 00:00:00

abstract：:Verapamil hydrochloride, a prototype calcium antagonist, is now marketed in the United States for the acute treatment of supraventricular tachyarrhythmias and for chronic management of vasospastic and chronic stable angina. It inhibits the slow inward channel in in the heart and blocks calcium influx in smooth muscle....

journal_title：Pharmacotherapy

authors： Baky SH,Singh BN

更新日期：1982-11-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the relationship between two widely used, generic health-related quality of life (HRQOL) measures, Short Form-12 (SF-12) and EuroQol's EQ-5D, and potentially inappropriate drug use in an elderly cohort. DESIGN:Longitudinal retrospective cohort study. DATA SOURCE:Medical Expenditure Pane...

journal_title：Pharmacotherapy

authors： Franic DM,Jiang JZ

更新日期：2006-06-01 00:00:00

abstract：:Synercid (RP 59500), the first injectable streptogramin antibiotic, is composed of two semisynthetic pristinamycin derivatives, quinupristin and dalfopristin. Individually, each component has bacteriostatic activity against staphylococci and streptococci, but together, the agents exhibit synergy, leading to bactericid...

journal_title：Pharmacotherapy

authors： Delgado G Jr,Neuhauser MM,Bearden DT,Danziger LH

更新日期：2000-12-01 00:00:00

abstract：:This commentary from the 2010 Task Force on Acute Care Practice Model of the American College of Clinical Pharmacy was developed to compare and contrast the "unit-based" and "service-based" orientation of the clinical pharmacist within an acute care pharmacy practice model and to offer an informed opinion concerning w...

journal_title：Pharmacotherapy

authors： American College of Clinical Pharmacy.,Haas CE,Eckel S,Arif S,Beringer PM,Blake EW,Lardieri AB,Lobo BL,Mercer JM,Moye P,Orlando PL,Wargo K

更新日期：2012-02-01 00:00:00

abstract：:Methemoglobin, a form of hemoglobin that does not bind oxygen, is produced when iron in red blood cells is oxidized from the ferrous state to the ferric state. Methemoglobinemia develops in the presence of oxidizing agents, such as benzocaine-containing topical anesthetic sprays, and it is characterized by cyanosis. I...

journal_title：Pharmacotherapy

authors： Throm MJ,Stevens MD,Hansen C

更新日期：2007-08-01 00:00:00

abstract：:Ischemic stroke is a prevalent disease with a large burden on the health system. Preventive strategies, therefore, are paramount. Primary prevention is aimed at reducing the risk of stroke in asymptomatic people. The most effective prevention is through control of modifiable risk factors. Due to the large amount of li...

journal_title：Pharmacotherapy

authors： Baker WL,Marrs JC,Davis LE,Nutescu EA,Rowe AS,Ryan M,Splinter MY,Vardeny O,Fagan SC

更新日期：2013-06-01 00:00:00

abstract：:Outpatient transesophageal echocardiography was performed in a 69-year-old man with a history of aortic valve repair. During the procedure the patient became markedly cyanotic and hypotensive. Oxygen saturation measured by pulse oximetry decreased from 97% to the mid-80s. The man's condition continued to deteriorate. ...

journal_title：Pharmacotherapy

authors： Wurdeman RL,Mohiuddin SM,Holmberg MJ,Shalaby A

更新日期：2000-06-01 00:00:00

abstract：INTRODUCTION:Vancomycin (VAN) is associated with an increased risk of acute kidney injury (AKI). Evidence is conflicting regarding the risk of AKI when VAN is combined with an antipseudomonal β-lactam. OBJECTIVES:To determine the comparative incidence of AKI when VAN is combined with piperacillin-tazobactam (PTZ) or m...

journal_title：Pharmacotherapy

authors： Robertson AD,Li C,Hammond DA,Dickey TA

更新日期：2018-12-01 00:00:00

abstract：:Cancer therapeutics is undergoing a revolution with the advent of new drugs that can selectively target molecules responsible for carcinogenesis and tumor growth. The type and mechanism of these targeting drugs vary. Some are small molecules that specifically target a binding site on a receptor or signal transduction ...

journal_title：Pharmacotherapy

authors： Jarkowski A 3rd,Glode AE,Spangenthal EJ,Wong MK

更新日期：2011-01-01 00:00:00

abstract：:A 58-year-old man experienced an asthma exacerbation after administration of nicotine nasal spray for smoking cessation. His medical history was significant for asthma, chronic obstructive pulmonary disease, hypertension, and tobacco use when he was prescribed nicotine nasal spray for smoking cessation in an outpatien...

journal_title：Pharmacotherapy

authors： Roth MT,Westman EC

更新日期：2002-06-01 00:00:00

abstract：:Carbamazepine is a potent anticonvulsant agent with proven efficacy in the treatment of partial and tonic-clonic seizures. An epileptic child treated with therapeutic dosages of carbamazepine developed severe hepatitis and hepatic insufficiency. She had a positive response to withdrawal of the drug and administration ...

journal_title：Pharmacotherapy

authors： Morales-Diaz M,Pinilla-Roa E,Ruiz I

更新日期：1999-02-01 00:00:00

abstract：:A 23-year-old man was brought to the emergency department after eating four boxes of brodifacoum-containing rodenticide over a 4-day interval and pieces from approximately two bottles of glass over the previous 2 weeks. He was asymptomatic but his prothrombin time was markedly elevated with an international normalized...

journal_title：Pharmacotherapy

authors： Tsutaoka BT,Miller M,Fung SM,Patel MM,Olson KR

更新日期：2003-09-01 00:00:00

abstract：:Children warrant access to care from clinical pharmacists trained in pediatrics. The American College of Clinical Pharmacy Pediatrics Practice and Research Network (ACCP Pediatrics PRN) released an opinion paper in 2005 with recommendations for improving the quality and quantity of pediatric pharmacy education in coll...

journal_title：Pharmacotherapy

authors： Bhatt-Mehta V,Buck ML,Chung AM,Farrington EA,Hagemann TM,Hoff DS,LaRochelle JM,Pettit RS,Phan H,Potts AL,Smith KP,Parrish RH 2nd

更新日期：2013-02-01 00:00:00

abstract：:Tobacco use continues to be a major cause of morbidity and mortality. Even with behavioral and pharmacologic treatment, long-term tobacco cessation rates are low. Electronic nicotine delivery systems, commonly referred to as electronic cigarettes or e-cigarettes, are increasingly used for tobacco cessation. Because e-...

journal_title：Pharmacotherapy

authors： Franks AS,Sando K,McBane S

更新日期：2018-05-01 00:00:00

abstract：:Infantile spasms describe a pediatric epilepsy syndrome characterized by frequent clusters of brief symmetric muscle contractions; the condition is often associated with developmental delay. When infantile spasms are accompanied by hypsarrhythmia on electroencephalogram, the condition is labeled West syndrome. The mai...

journal_title：Pharmacotherapy

authors： Pesaturo KA,Spooner LM,Belliveau P

更新日期：2011-03-01 00:00:00

abstract：:We evaluated the efficacy and tolerability of amphotericin B triglyceride emulsion in 16 patients with acquired immunodeficiency syndrome-related candidal esophagitis and cryptococcosis, compared with standard amphotericin B in 24 patients. Compared with the conventional formulation, the fat emulsion was administered ...

journal_title：Pharmacotherapy

authors： Manfredi R,Chiodo F

更新日期：1998-09-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the efficacy of a single, low-dose injection of botulinum toxin type A in relieving pain in Korean patients with piriformis syndrome resistant to conventional therapy, and to assess the drug's influence on these patients' quality of life. DESIGN:Prospective, single-site, open-label trial. ...

journal_title：Pharmacotherapy

authors： Yoon SJ,Ho J,Kang HY,Lee SH,Kim KI,Shin WG,Oh JM

更新日期：2007-05-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy and safety of a new combination product, enalapril-diltiazem ER, when administered over the long term. DESIGN:Open-label, titration to response, with treatment lasting 46 weeks after a 6-week, double-blind phase. SETTING:Medical clinics in the private and academic sectors. PA...

journal_title：Pharmacotherapy

authors： Applegate W,Cohen JD,Wolfson P,Davis A,Green S

更新日期：1997-01-01 00:00:00

abstract：:The role of the formulary system for effective cost containment is becoming increasingly important. With antimicrobial agents taking up a large proportion of most pharmaceutical budgets, this group of agents is an obvious target for cost reduction. The responsible interchange of selected antimicrobial agents offers a ...

journal_title：Pharmacotherapy

authors： Wright DB

更新日期：1991-01-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is an acute inflammatory process that impairs the ability of the lungs to oxygenate and ultimately leads to respiratory failure. Patients who develop ARDS often have prolonged and complicated hospital courses putting them at risk for intensive care unit (ICU) delirium. Patien...

journal_title：Pharmacotherapy

authors： Torbic H,Duggal A

更新日期：2018-04-01 00:00:00

abstract：STUDY OBJECTIVE:To review quantitatively and qualitatively the U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (AERS) database to provide clinicians with a general understanding of the comparative occurrence of clinically meaningful adverse events associated with 15 antimicrobial new molecular en...

journal_title：Pharmacotherapy

authors： Khadem TM,van Manen RP,Brown J

更新日期：2014-12-01 00:00:00

abstract：:The clinical and economic impacts of bacterial resistance are substantial. The development of bacterial resistance during a course of therapy often leads to clinical failure, prolonged hospitalization, increased morbidity, mortality, and increased health care costs. Resistance has been reported to occur most frequentl...

journal_title：Pharmacotherapy

authors： Barriere SL

更新日期：1992-01-01 00:00:00