Abstract:
:The aim of the study was to compare the effect of halothane anaesthesia on sympathetic nerve discharge in mechanically normoventilated and spontaneously breathing rats. Renal sympathetic nerve activity (rSNA), mean arterial pressure (MAP) and heart rate (HR) were measured in the conscious state and at the inspiratory halothane concentrations of 0.6%, 1.2% and 2.4% in one mechanically normoventilated and one spontaneously breathing group, while a third group was subjected to controlled hypoventilation at 1.2% halothane concentration. Halothane in blood was determined in two separate groups at 1.2%. In an additional group of spontaneously breathing rats, PaCO2 was analysed during consciousness and the halothane concentrations of 1.2% and 2.4%. There was a pronounced decrease in rSNA, MAP and HR at all levels of anaesthesia in the mechanically ventilated rats. However, rSNA, HR and MAP were significantly higher in the spontaneously breathing rats at increasing levels of halothane anaesthesia. Controlled hypoventilation at 1.2% halothane increased the variables significantly. In spontaneously breathing animals, PaCO2 increased significantly during the halothane exposure. The concentration of halothane in blood was significantly higher in the spontaneously breathing rats. Thus, the halothane-induced respiratory depression in the spontaneously breathing rats preserved rSNA during halothane anaesthesia, possibly via CO2-mediated chemoreceptor stimulation.
journal_name
Acta Anaesthesiol Scandjournal_title
Acta anaesthesiologica Scandinavicaauthors
Delle M,Thorén P,Sonander H,Majcherszyk S,Ricksten SEdoi
10.1111/j.1399-6576.1988.tb02757.xsubject
Has Abstractpub_date
1988-07-01 00:00:00pages
413-9issue
5eissn
0001-5172issn
1399-6576journal_volume
32pub_type
杂志文章abstract::A young trauma patient developed severe adult respiratory distress syndrome (ARDS), right heart failure, hepatic congestion and an extreme hepatomegaly but no hepatic failure. The patient needed 100% oxygen during ventilatory support for 80 days and was weaned from the ventilator after more than 100 days. The hepatome...
journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1399-6576.2002.460724.x
更新日期:2002-08-01 00:00:00
abstract::The MDO (Mehrdraht Dortmund Oberfläche) oxygen electrode was used for studies of oxygen pressure fields in rat skeletal muscle. With this multiwire oxygen electrode, the three-dimensional oxygen pressure field was measured and presented as a two-dimensional frequency distribution, i.e., a histogram. Statistical analys...
journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1399-6576.1980.tb01525.x
更新日期:1980-06-01 00:00:00
abstract:BACKGROUND:Pentoxifylline improves tissue oxygenation and intestinal blood flow in models of haemorrhagic shock, and it has been used for the treatment of intermittent claudication due to its beneficial effects on haemorheology. We investigated the effects of pentoxifylline on whole blood viscosity during packed red-bl...
journal_title:Acta anaesthesiologica Scandinavica
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journal_title:Acta anaesthesiologica Scandinavica
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journal_title:Acta anaesthesiologica Scandinavica
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doi:10.1111/j.1399-6576.1979.tb01484.x
更新日期:1979-12-01 00:00:00
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journal_title:Acta anaesthesiologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1985-01-01 00:00:00
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journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
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更新日期:1992-08-01 00:00:00
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doi:10.1111/j.0001-5172.2004.00422.x
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pub_type: 杂志文章
doi:10.1111/j.1399-6576.1994.tb03970.x
更新日期:1994-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:1987-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Acta anaesthesiologica Scandinavica
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更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-05-01 00:00:00
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更新日期:1981-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-03-01 00:00:00
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journal_title:Acta anaesthesiologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1399-6576.1985.tb02304.x
更新日期:1985-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-11-01 00:00:00
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journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1399-6576.1990.tb03102.x
更新日期:1990-07-01 00:00:00
abstract::The skin conductance response (SCR) (the "sympatho-galvanic reflex") was studied in volunteers and in a few patients undergoing spinal analgesia. Electrical stimulation over the clavicle, breath-holding during inspiration, a short, deep breath and a sharp sound provoked a marked change in conductance not only in the h...
journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1399-6576.1984.tb02123.x
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:Intravenous administration of vasopressin during cardiopulmonary resuscitation (CPR) has been shown to improve myocardial and cerebral blood flow. Aortic balloon occlusion during CPR may also augment myocardial and cerebral blood flow and can be used as a central route for the administration of resuscitative...
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pub_type: 杂志文章
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更新日期:2000-11-01 00:00:00
abstract::The effects of nitroglycerin (TNG) infusion during ventilation with FIO2 = 1.0 on central haemodynamics and the distribution of ventilation-perfusion (VA/Q) were studied with the multiple inert gas elimination technique in eight patients after coronary bypass surgery. Administration of TNG resulted in a significant de...
journal_title:Acta anaesthesiologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1399-6576.1984.tb02004.x
更新日期:1984-02-01 00:00:00
abstract:BACKGROUND:Gas exchange during high-frequency jet ventilation (HFJV) for prolonged rigid bronchoscopy (RBS) is usually monitored by arterial blood gas analysis. Capnography of expired gases during brief HFJV discontinuation may be a reliable and noninvasive supplemental method. Capnography can be performed either for s...
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pub_type: 杂志文章
doi:10.1034/j.1399-6576.2000.440406.x
更新日期:2000-04-01 00:00:00