Abstract:
:To investigate the haemodynamic changes after physical training in patients with left ventricular aneurysm, 60 uncomplicated patients, mean age 51 +/- 10 years, underwent a maximal ergometric test in the supine position with haemodynamic monitoring (Swan-Ganz catheter) 37 +/- 10 days from acute myocardial infarction and after a 4-week period of supervised physical training. The size of aneurysmatic dilatation (aneurysm area-total end-diastolic area ratio %) and resting left ventricular ejection fraction (Dodge's method) were obtained from a two-dimensional echocardiogram (apical approach) performed on the same day of the pre-training ergometric test. On average, left ventricular ejection fraction was reduced (39 +/- 11%), with values below 35% in 25 patients. Resting pulmonary wedge pressure was greater than 12 mm Hg in 42 patients and greater than 20 mm Hg at peak exercise in 48 subjects. The entity of aneurysmatic dilatation was significantly related to left ventricular ejection fraction (r = 0.60, less than 0.001), but not to the values of pulmonary wedge pressure at rest (r = 0.22) or at peak exercise (r = 0.11). No complication during the physical training period was observed. After training, maximal work capacity increased (77 +/- 29 vs 94 +/- 35 W, P less than 0.001) as well as cardiac output and stroke volume with a slight change in pulmonary wedge pressure (24 +/- 7 vs 28 +/- 7 mm Hg, P less than 0.05). At matched submaximal exercise, heart rate decreased (P less than 0.05), stroke volume and arterio-venous oxygen difference increased (P less than 0.05) without significant changes in cardiac output and left ventricular filling pressure.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Giordano A,Giannuzzi P,Tavazzi Ldoi
10.1093/eurheartj/9.suppl_f.11subject
Has Abstractpub_date
1988-04-01 00:00:00pages
11-5eissn
0195-668Xissn
1522-9645journal_volume
9 Suppl Fpub_type
杂志文章abstract::Antiarrhythmic agents may depress cardiac contractility and worsen heart failure. Flecainide is an effective antiarrhythmic drug, but when administered orally in patients with left ventricular (LV) dysfunction, its effect on LV function is unknown. To assess the effects of flecainide on cardiac function, LV ejection f...
journal_title:European heart journal
pub_type: 临床试验,杂志文章
doi:10.1093/eurheartj/8.7.754
更新日期:1987-07-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a062126
更新日期:1986-08-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a060259
更新日期:1992-06-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a062318
更新日期:1987-05-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a060841
更新日期:1995-12-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/9.suppl_e.37
更新日期:1988-04-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a059513
更新日期:1989-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.1999.1714
更新日期:1999-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a014878
更新日期:1996-03-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/8.7.689
更新日期:1987-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1053/euhj.1999.1877
更新日期:2000-03-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehv343
更新日期:2015-10-21 00:00:00
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journal_title:European heart journal
pub_type: 临床试验,杂志文章
doi:10.1093/oxfordjournals.eurheartj.a062428
更新日期:1988-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/eurheartj/ehp160
更新日期:2009-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/eurheartj/ehaa868
更新日期:2020-12-16 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehs013
更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ehj.2004.01.016
更新日期:2004-03-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a062561
更新日期:1988-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/eurheartj/ehi198
更新日期:2005-08-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehaa229
更新日期:2020-10-21 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.2000.2445
更新日期:2001-07-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehw121
更新日期:2016-08-21 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehm338
更新日期:2008-05-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a062107
更新日期:1986-07-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.2000.2368
更新日期:2001-02-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1093/eurheartj/ehm503
更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/eurheartj/10.suppl_d.42
更新日期:1989-09-01 00:00:00