Congenital valvular aortic stenosis in adults.

abstract：AIMS:Chronic kidney disease (CKD) was found to be an independent risk factor for all-cause mortality as well as adverse cardiovascular disease (CVD) events in high-risk populations. Findings from population-based studies are scarce and inconsistent. We investigated the gender-specific association of CKD with all-cause ...

journal_title：European heart journal

authors： Meisinger C,Döring A,Löwel H,KORA Study Group.

更新日期：2006-05-01 00:00:00

abstract：:Clinicians have long suspected that hypertrophied hearts have an inadequate coronary circulation. This clinical suspicion resulted from the observation that a large proportion of patients with left ventricular hypertrophy who have normal coronary arteriograms complain of angina and have ischaemia-like ST segment depre...

journal_title：European heart journal

authors： Kaski JC

更新日期：1993-11-01 00:00:00

abstract：AIMS:Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Elevation of myocyte cyclic GMP levels by local actions of endogenous atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) or by pharmacological inhibition of phosphodiesterase-5 was shown to counter-regulate p...

journal_title：European heart journal

authors： Frantz S,Klaiber M,Baba HA,Oberwinkler H,Völker K,Gaβner B,Bayer B,Abeβer M,Schuh K,Feil R,Hofmann F,Kuhn M

更新日期：2013-04-01 00:00:00

abstract：AIMS:To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA stenting in the current bare-metal stent era. METHODS:We reviewed outcomes among 142 consecutive patients who underwent protected or unprotected LMCA stenting since...

journal_title：European heart journal

authors： Kelley MP,Klugherz BD,Hashemi SM,Meneveau NF,Johnston JM,Matthai WH Jr,Banka VS,Herrmann HC,Hirshfeld JW Jr,Kimmel SE,Kolansky DM,Horwitz PA,Schiele F,Bassand JP,Wilensky RL

更新日期：2003-09-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the effect of valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and to evaluate whether conflicting results reported by previous studies could be due to differences in their methodological approaches. METHODS AND RESULTS:Four hundred and forty-nine patient...

journal_title：European heart journal

authors： Bannay A,Hoen B,Duval X,Obadia JF,Selton-Suty C,Le Moing V,Tattevin P,Iung B,Delahaye F,Alla F,AEPEI Study Group.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Recent identification of mutations in the beta-myosin heavy chain gene (MYH7), a major responsible gene for HCM, has provided the opportunity to characterize genotype-phenotype correlation in HCM families. In this study we analysed the phenotypic expression of two beta-myosin heavy chain (beta MHC) mutations...

journal_title：European heart journal

authors： Marian AJ,Mares A Jr,Kelly DP,Yu QT,Abchee AB,Hill R,Roberts R

更新日期：1995-03-01 00:00:00

abstract：:The efficacy and safety of a single infusion of cibenzoline, a class I antiarrhythmic drug, were assessed in 86 patients presenting with a supraventricular tachyarrhythmia following heart surgery in a placebo-controlled double-blind parallel study. Cibenzoline was effective in 13 patients (30%) vs three patients (6.9%...

journal_title：European heart journal

authors： Ollitrault J,Quilliet L,Scheck F,Lelong B,Richard A,Jarry G,Guize L

更新日期：1994-09-01 00:00:00

abstract：AIMS:Characteristics of sudden cardiac arrest (SCA) during sports offers a novel (and unexplored) setting to assess factors associated with disparities in outcomes across regions. METHODS AND RESULTS:From a prospective 5-year community-based French registry concerning SCA during sports in 10-75 year-olds, we evaluated...

journal_title：European heart journal

authors： Marijon E,Bougouin W,Celermajer DS,Perier MC,Benameur N,Lamhaut L,Karam N,Dumas F,Tafflet M,Prugger C,Mustafic H,Rifler JP,Desnos M,Le Heuzey JY,Spaulding CM,Avillach P,Cariou A,Empana JP,Jouven X

更新日期：2013-12-01 00:00:00

abstract：AIM:To examine the association of left ventricular hypertrophy (LVH) on admission electrocardiography with adverse outcomes in acute coronary syndrome (ACS) patients. METHODS AND RESULTS:A total of 7443 non-ST-elevation ACS patients in Global Utilization of STrategies to Open occluded arteries (GUSTO) IV ACS trial had...

journal_title：European heart journal

authors： Westerhout CM,Lauer MS,James S,Fu Y,Wallentin L,Armstrong PW,GUSTO IV ACS Investigators.

更新日期：2007-09-01 00:00:00

abstract：AIMS:Older people increasingly constitute a large proportion of the acute coronary syndrome (ACS) population. We examined the relationship of age with receipt of more intensive management and secondary prevention medicine. Then, the comparative association of intensive management (reperfusion/angiography) over a conser...

journal_title：European heart journal

authors： Zaman MJ,Stirling S,Shepstone L,Ryding A,Flather M,Bachmann M,Myint PK

更新日期：2014-06-14 00:00:00

abstract：Aims:To determine tolerability and the optimal dose regimen of the soluble guanylate cyclase stimulator vericiguat in patients with chronic heart failure and preserved ejection fraction (HFpEF). Methods and results:SOCRATES-PRESERVED was a prospective, randomized, placebo-controlled double-blind, Phase 2b dose-finding...

journal_title：European heart journal

authors： Pieske B,Maggioni AP,Lam CSP,Pieske-Kraigher E,Filippatos G,Butler J,Ponikowski P,Shah SJ,Solomon SD,Scalise AV,Mueller K,Roessig L,Gheorghiade M

更新日期：2017-04-14 00:00:00

abstract：AIMS:To assess the prognostic significance of infarct core tissue characteristics using cardiac magnetic resonance (CMR) imaging in survivors of acute ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:We performed an observational prospective single centre cohort study in 300 reperfused STEMI patients (m...

journal_title：European heart journal

authors： Carrick D,Haig C,Rauhalammi S,Ahmed N,Mordi I,McEntegart M,Petrie MC,Eteiba H,Hood S,Watkins S,Lindsay M,Mahrous A,Ford I,Tzemos N,Sattar N,Welsh P,Radjenovic A,Oldroyd KG,Berry C

更新日期：2016-04-01 00:00:00

abstract：AIMS:The objectives of this study were to determine the association of waist circumference (WC) and waist-to-hip ratio (WHR) with the risk of incident cardiovascular disease (CVD) events and to determine whether the strength of association of WC and WHR with CVD risk is different. METHODS AND RESULTS:This meta-regress...

journal_title：European heart journal

authors： de Koning L,Merchant AT,Pogue J,Anand SS

更新日期：2007-04-01 00:00:00

abstract：AIMS:Whereas endogenous carbon monoxide (CO) is cytoprotective at physiologic levels, excess CO concentrations are associated with cardiometabolic risk and may represent an important marker of progression from subclinical to clinical cardiovascular disease (CVD). METHODS AND RESULTS:In 1926 participants of the Framing...

journal_title：European heart journal

authors： Cheng S,Enserro D,Xanthakis V,Sullivan LM,Murabito JM,Benjamin EJ,Polak JF,O'Donnell CJ,Wolf PA,O'Connor GT,Keaney JF,Vasan RS

更新日期：2014-11-07 00:00:00

abstract：:A 54 year old woman with isolated stenosis of the left coronary ostium died following cardiac catheterisation and emergency coronary artery bypass surgery. Histological examination showed the ostial narrowing to be a local and discrete plaque of atherosclerosis. Like most reported cases this patient was a young woman ...

journal_title：European heart journal

authors： Stewart JT,Ward DE,Davies MJ,Pepper JR

更新日期：1987-08-01 00:00:00

abstract：:There is mounting evidence to support the influence of inflammation in the pathogenesis of atrial fibrillation (AF). Indeed, AF is associated with increased levels of known inflammatory markers, even after adjustment for confounding factors. The renin-angiotensin-aldosterone system (RAAS) appears to play a key role in...

journal_title：European heart journal

authors： Boos CJ,Anderson RA,Lip GY

更新日期：2006-01-01 00:00:00

abstract：AIMS:Right ventricular dysfunction (RVD) is an important determinant of functional status and survival in various diseases states. Data are sparse on the epidemiology and outcome of patients with severe RVD. This study examined the characteristics, aetiology, and survival of patients with severe RVD. METHODS AND RESUL...

journal_title：European heart journal

authors： Padang R,Chandrashekar N,Indrabhinduwat M,Scott CG,Luis SA,Chandrasekaran K,Michelena HI,Nkomo VT,Pislaru SV,Pellikka PA,Kane GC

更新日期：2020-03-21 00:00:00

abstract：AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

journal_title：European heart journal

authors： Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

更新日期：2004-09-01 00:00:00

abstract：AIMS:Obesity is a recognized risk factor for atrial fibrillation (AF), partly because of the association between body mass index (BMI) and atrial volume. We aimed to determine whether other factors relating to body size were related to AF. METHODS AND RESULTS:Data were derived from a random population sample of 6903 m...

journal_title：European heart journal

authors： Rosengren A,Hauptman PJ,Lappas G,Olsson L,Wilhelmsen L,Swedberg K

更新日期：2009-05-01 00:00:00

abstract：:Diagnosis of myocarditis has improved with the application of new techniques such as immunohistochemistry, polymerase chain reaction, in situ hybridization and Southern blot in endomyocardial biopsies. Treatment of inflammatory heart disease is still difficult and not yet validated by a study with patient numbers suff...

journal_title：European heart journal

authors： Maisch B,Hufnagel G,Schönian U,Hengstenberg C

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Patients with known or suspected coronary disease are often investigated to facilitate risk assessment. We sought to examine the cost-effectiveness of strategies based on exercise echocardiography and exercise electrocardiography. METHODS AND RESULTS:We studied 7656 patients undergoing exercise testing; of ...

journal_title：European heart journal

authors： Marwick TH,Shaw L,Case C,Vasey C,Thomas JD

更新日期：2003-06-01 00:00:00

abstract：:In untreated congestive heart failure, aldosterone plasma concentrations are elevated in proportion to the severity of the disease and are further increased by the use of diuretic treatment. Angiotensin II, plasma potassium concentration, and corticotropin are the major stimulators of aldosterone synthesis. During ang...

journal_title：European heart journal

authors： Zannad F

更新日期：1995-12-01 00:00:00

abstract：AIMS:A potential role for cardiovascular disease (CVD) risk factors in the aetiology of suicide has not been comprehensively examined. In addition to being small in scale and poorly characterized, existing studies very rarely sample Asian populations in whom risk factor-suicide relationships may plausibly differ to Cau...

journal_title：European heart journal

authors： Jee SH,Kivimaki M,Kang HC,Park IS,Samet JM,Batty GD

更新日期：2011-11-01 00:00:00

abstract：:After single chamber atrial pacemaker implantation, serial electrophysiologic studies were performed noninvasively at intervals of 3 months over a total period of 3 years in 24 patients with symptomatic sinus node dysfunction. All patients underwent invasive electrophysiologic studies before pacemaker implantation and...

journal_title：European heart journal

authors： van Mechelen R,Segers A,Hagemeijer F

更新日期：1984-08-01 00:00:00

abstract：AIM:Ventricular fibrosis is promoted by many effectors that chronically activate phospholipase D (PLD), and induces cardiac dysfunction and heart failure in cardiovascular diseases. Since ethanolamine is a product of PLD, we hypothesised that an administration of an analogue of ethanolamine, N-methylethanolamine (MEA),...

journal_title：European heart journal

authors： Yamamoto K,Takahashi Y,Mano T,Sakata Y,Nishikawa N,Yoshida J,Oishi Y,Hori M,Miwa T,Inoue S,Masuyama T

更新日期：2004-07-01 00:00:00

abstract：:Right ventricular dysplasia (RVD) is a cardiac anomaly characterized by replacement of right ventricular myocardium by adipose and fibrous tissue that was first described at autopsy, and is now being recognized pre-mortem. Sudden death and ventricular arrhythmias are the most common clinical manifestation of the condi...

journal_title：European heart journal

authors： Strain J

更新日期：1989-09-01 00:00:00

abstract：AIMS:We designed this study in order to determine the effect of insulin on cardiac function in overweight and obese subjects during exercise. METHODS AND RESULTS:The cardiac function of 62 normal glucose tolerant subjects, aged 30-40 and divided into normal weight (group 1, n=22, BMI 20-24.9 kg/m(2)), overweight (grou...

journal_title：European heart journal

authors： Sasso FC,Carbonara O,Nasti R,Marfella R,Esposito K,Rambaldi P,Mansi L,Salvatore T,Torella R,Cozzolino D

更新日期：2005-06-01 00:00:00

abstract：AIMS:Reperfusion injury following acute myocardial infarction impacts not only on the myocardium but also on the coronary microcirculation, and microembolization from the culprit lesion contributes to microvascular obstruction. Prior experimental studies have not accounted for microembolization in ischaemia/reperfusion...

journal_title：European heart journal

authors： Skyschally A,Walter B,Heusch G

更新日期：2013-11-01 00:00:00

abstract：:The study of 'atrial vulnerability' is often clinically indicated but it requires the use of invasive intracardiac stimulation. The purpose of the study was to assess the use of oesophageal pacing in the evaluation of atrial tachyarrhythmias (ATA). Fifty-five patients with documented ATA (group I) and 60 without (grou...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-08-01 00:00:00

abstract：:MitraClip therapy consists of percutaneous edge-to-edge coaptation of the mitral leaflets that is analogous to the surgical Alfieri technique. The safety profile of the MitraClip device is favourable, and survival outcomes in high-surgical-risk patients are superior to historical controls. However, questions remain re...

journal_title：European heart journal

authors： Rogers JH,Franzen O

更新日期：2011-10-01 00:00:00