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Multidetector computed tomography shows intramyocardial fat deposition.

Abstract：

BACKGROUND:Intramyocardial fat deposition occurs as an age-related process and in multiple pathologic processes. OBJECTIVE:We evaluated the presence of left ventricular (LV) and right ventricular (RV) intramyocardial fat with 64-slice multidetector computed tomography (MDCT). METHODS:One hundred persons with no history of coronary artery disease (47 women, 53 men; mean age [+/- SD], 53 +/- 12.2 years) and 25 patients with CT findings of myocardial infarction (17 men, 8 women; mean age, 71.3 +/- 9.6 years) were studied for intramyocardial fat in defined segments of the ventricles (17 LV and 10 RV segments) at 3 levels. Fat deposition was defined as density range of -30 to -190 Hounsfield units on images both before and after contrast. RESULTS:In healthy persons, LV intramyocardial fat was primarily located in the basal segments (5% anteroseptal, 5% inferior), and RV intramyocardial fat was primarily located in the anterolateral (24% of base, 23% of mid) and inferolateral (27% base, 27% mid) segments. Older age was associated with an increased odds of RV (sex-adjusted odds ratio [OR] per decade increment, 1.61; 95% confidence interval [CI], 1.11-2.33; P = 0.012) but not LV (OR, 0.97; 95% CI, 0.67-1.40; P = 0.85) intramyocardial fat. Compared with women, men had a lower risk of LV (95% CI, 0.1-0.64; P = 0.004) but not RV (95% CI, 0.35-1.87; P = 0.62) intramyocardial fat. Patients with old myocardial infarction (>3 years) had increased percentage of fat in infarcted left ventricles at all 3 levels (P

journal_name

J Cardiovasc Comput Tomogr

journal_title

Journal of cardiovascular computed tomography

authors

Raney AR,Saremi F,Kenchaiah S,Gurudevan SV,Narula J,Narula N,Channual S

doi

10.1016/j.jcct.2008.01.004

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

152-63

issue

3

eissn

1934-5925

issn

1876-861X

pii

S1934-5925(08)00049-X

journal_volume

2

pub_type

杂志文章

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