Abstract:
BACKGROUND:Sudden cardiac death is the leading cause of death among firefighters in the United States. Fire departments commonly maintain physical examination protocols, often with exercise stress testing, to detect risk of coronary heart disease. OBJECTIVE:We sought to determine whether coronary calcium detected by electron beam computed tomography (EBCT) adds incremental risk stratification beyond the traditional risk factors in asymptomatic community-based firefighters. METHODS:Three hundred ninety nine asymptomatic firefighters underwent a coronary calcium scan on a GE/Imatron C-150 Ultrafast EBCT scanner, using standardized imaging protocols. Framingham risk factor data were obtained on each patient by using a questionnaire. Agatston scores were derived and compared with national database of Agatston scores for asymptomatic populations on the basis of age and sex, allowing determination of a calcium percentile for each score. RESULTS:Coronary calcium was found only in men >34 years of age. Of the 53% who had positive scans (Agatston score > 0), 87% had higher than average Agatston scores compared with a national database (P < 0.01). Agatston score above the 75th percentile was found in 57% of firefighters. No correlation was observed between traditional risk factors and those with and without coronary calcium. CONCLUSIONS:Firefighters have a high burden of calcified coronary atherosclerosis, greater than anticipated on the basis of age and coronary risk factors.
journal_name
J Cardiovasc Comput Tomogrjournal_title
Journal of cardiovascular computed tomographyauthors
Santora LJ,Pillutla P,Norris T,Santora R,Brandt R,Jenkins M,Robinson M,Santora N,Budoff MJdoi
10.1016/j.jcct.2012.07.003subject
Has Abstractpub_date
2013-01-01 00:00:00pages
46-50issue
1eissn
1934-5925issn
1876-861Xpii
S1934-5925(12)00414-5journal_volume
7pub_type
杂志文章abstract:BACKGROUND:The present study aimed to assess the reliability and reproducibility of coronary computed tomography angiography (CCTA) for the serial quantitative assessment of plaque volume. METHODS:Patients who underwent repeated CCTA scans within 90 days were retrospectively screened and enrolled. Clinical data and CC...
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journal_title:Journal of cardiovascular computed tomography
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章,评审
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更新日期:2020-01-01 00:00:00
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