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Low contrast and radiation dose coronary CT angiography using a 320-row system and a refined contrast injection and timing method.

Abstract：

BACKGROUND:Among CT scanners, 320-row instruments feature decreased photon energy and yield strong contrast enhancement. Consequently, the contrast medium (CM) dose can be reduced. The results of low-tube-voltage coronary CT angiography (CCTA) performed on 320-row scanners have not been adequately assessed. OBJECTIVE:We evaluated the effects of a low-contrast-dose protocol on the image quality of CCTA using 80 kVp tube voltage, iterative reconstruction (IR), and a 320-row scanner. METHODS:We randomly assigned 90 patients (mean body weight, 56.5 ± 11.0 kg) to 1 of 3 CCTA protocols. Under protocol A, 30 were scanned using a conventional 120-kVp protocol and a standard CM dose (280 mg iodine/kg body weight [mgI/kg]). Another 30 underwent scanning at 80 kVp with a 25% CM dose reduction (210 mgI/kg; protocol B). Under protocol C, the remaining 30 patients were scanned at 80 kVp with a 50% CM dose reduction (140 mgI/kg). The 120 and 80 kVp images were processed with IR. Images obtained under the 3 protocols were subjected to quantitative and qualitative analysis. RESULTS:The amount of CM used in protocol A, B, and C was 43.6 ± 10.1, 30.3 ± 4.4, and 21.0 ± 4.0 mL, respectively. Mean CT attenuation of the coronary arteries tended to be higher under protocol B than the other 2 protocols. The contrast-to-noise ratio was significantly higher under protocol B. The mean visual scores were significantly higher for protocols A and B than protocol C. The mean effective radiation dose was significantly lower under the 80-kVp protocol. CONCLUSION:With a 320-row scanner and our refined CM injection and timing protocol, it is technically feasible to obtain sufficient vascular enhancement with a reduction in the CM and/or radiation dose at 80-kVp CCTA with IR.

journal_name

J Cardiovasc Comput Tomogr

journal_title

Journal of cardiovascular computed tomography

authors

Oda S,Utsunomiya D,Yuki H,Kai N,Hatemura M,Funama Y,Kidoh M,Yoshida M,Namimoto T,Yamashita Y

doi

10.1016/j.jcct.2014.12.002

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

19-27

issue

eissn

1934-5925

issn

1876-861X

pii

S1934-5925(14)00320-7

journal_volume

pub_type

杂志文章,随机对照试验

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Low contrast and radiation dose coronary CT angiography using a 320-row system and a refined contrast injection and timing method.