Abstract:
BACKGROUND:Data are limited on using 64-slice multidetector computed tomography (MDCT) as a gatekeeper to cardiac catheterization in patients with mild abnormalities on myocardial perfusion stress imaging (MPI). OBJECTIVE:We compared the rate of invasive coronary angiography (ICA) within 6 months after finding mildly abnormal MPI results before and after implementing 64-slice MDCT. METHODS:This retrospective cohort study included patients referred for follow-up based on a mildly abnormal MPI. Pre- and post-MDCT cohorts were matched according to age, sex, prior history of coronary artery disease (CAD), and presence of clinical symptoms (chest pain or exertional dyspnea or both). Case matching resulted in 154 patients in each cohort. The primary endpoint was the rate of ICA. RESULTS:From the clinical evaluation or MDCT results, 87 patients were referred for ICA, 60 (39%) in the pre-MDCT cohort and 27 (18%) in the post-MDCT cohort. Among those referred for ICA, 22 (14%) in the pre-MDCT cohort and 17 (11%) in the post-MDCT cohort underwent revascularization. Given the similar rate of revascularizations in both cohorts, we estimate that patients in the post-MDCT cohort were 86% less likely to receive ICA compared with patients in the pre-MDCT cohort (odds ratio = 0.14; 95% confidence interval, 0.06-0.33). During 6 months of follow-up, no clinical events were observed in either cohort for patients not referred to ICA. CONCLUSION:For patients with mildly abnormal MPI followed by clinical evaluation, MDCT examination was associated with a significant reduction in rate of referral to ICA.
journal_name
J Cardiovasc Comput Tomogrjournal_title
Journal of cardiovascular computed tomographyauthors
Hines JL,Danciu SC,Shah M,Borg MJ,Biga Cdoi
10.1016/j.jcct.2008.09.002subject
Has Abstractpub_date
2008-11-01 00:00:00pages
372-8issue
6eissn
1934-5925issn
1876-861Xpii
S1934-5925(08)00615-1journal_volume
2pub_type
杂志文章abstract:BACKGROUND:Cardiac computed tomography angiography (coronary CTA) has emerged as a non-invasive method of diagnosing coronary artery disease. The extent of utilization and uptake of this technology since initiation of its funding by the government of Ontario is unknown. OBJECTIVES:The aim of our study was to examine c...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2015.07.006
更新日期:2015-11-01 00:00:00
abstract::A 71-year-old man, a heavy smoker, was admitted for evaluation of "chest oppression" after every dinner. Cardiac CT with a beta-blocker showed coronary stenosis in the left circumflex. Although adenosine triphosphate-stress perfusion single-photon emission CT revealed no ischemia, Holter electrocardiography belatedly ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2014.06.005
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:There have been no reports about the diagnostic ability of coronary computed tomography angiography (CTA) in evaluating collateral channels used for retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI). OBJECTIVE:We investigated the ability and diagnostic accuracy of coronary CT...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2016.01.003
更新日期:2016-03-01 00:00:00
abstract::To comment that cardiac computed tomography angiography (CCTA) is an exciting tool in the evaluation of coronary artery disease (CAD) is an understatement. As a new method, however, differing clinical and reimbursement guidelines exist to guide the use of the method, resulting in confusion among referring and interpre...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章,评审
doi:10.1016/j.jcct.2007.11.004
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Technical advances to minimize radiation exposure because of imaging are in accord with the "as low as reasonably achievable" principle. OBJECTIVE:We aimed to determine whether coronary calcium scoring (CCS) by multidetector CT at a tube voltage of 100 kVp yields comparable results to the standard 120-kVp p...
journal_title:Journal of cardiovascular computed tomography
pub_type: 评论,杂志文章
doi:10.1016/j.jcct.2009.10.002
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:Catheter ablation (CA) is an established therapy for selected patients with atrial fibrillation (AF), but predictors of CA ablation outcome are still not fully elucidated. The aim of the study was to identify structural and morphological parameters from computed tomography (CT) as predictors of successful CA ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2018.06.005
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Neonates with complex congenital heart disease (CHD) are at risk of adverse events from anesthesia. CT angiography (CTA) performed free breathing and without sedation has not been reported for evaluation of complex CHD in neonates. OBJECTIVES:The aim was to evaluate the image quality and risk of free breath...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2013.11.006
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Coronary computed tomography angiography (CCTA) left ventricle (LV) volumes have prognostic value. LV measurements however can differ depending on post-processing software. Two common methods are the contour (CON) or attenuation (ATT) based methods. This study aims to determine differences in LV volume measu...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2019.08.003
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Enlargement of the LA is known to increase the risk of atrial fibrillation (AF) and its associated complications. However, the relation between other left atrial (LA) anatomical abnormalities and the risk of developing AF is less well described. OBJECTIVE:The aim of this study was to compare the prevalence ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2012.02.004
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:The threshold for the optimal computed tomography (CT) number in Hounsfield Units (HU) to quantify aortic valvular calcium on contrast-enhanced scans has not been standardized. Our aim was to find the most accurate threshold to predict paravalvular regurgitation (PVR) after transcatheter aortic valve replace...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2017.04.009
更新日期:2017-01-01 00:00:00
abstract::Magnetic particle imaging (MPI) is a new medical imaging technique which performs a direct measurement of magnetic nanoparticles, also known as superparamagnetic iron oxide. MPI can acquire quantitative images of the local distribution of the magnetic material with high spatial and temporal resolution. Its sensitivity...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2012.04.007
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. OBJECTIVE:We explored whether regional myocardial hypoenhan...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2009.12.003
更新日期:2010-03-01 00:00:00
abstract::A 62-year-old woman underwent percutaneous transhepatic obliteration of a giant portal-systemic shunt. Just after inserting a coil into the shunt, it slipped through the giant shunt and migrated to the right atrium. CT showed coil migration into the coronary sinus. ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2013.08.014
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Epicardial adipose tissue (EAT) is a metabolically active fat depot. Studies have investigated the effect of EAT thickness on outcomes of radiofrequency catheter ablation of atrial fibrillation (AF). However, data on the relationship between EAT thickness and outcome of cryoballoon-based pulmonary vein isola...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2015.03.011
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The objective of this study was to determine normal values for coronary artery volume (CAV) and individual vasculature and segment dimensions. METHODS:We examined 200 healthy volunteers with an Agatston score of 0 and a normal, high quality coronary CTA. Using 320 slice multidetector row CT and designated v...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2017.04.001
更新日期:2017-01-01 00:00:00
abstract::Pulmonary artery intramural hematoma is a very rare condition that can occur isolated or in patients with aortic dissection, usually of Stanford type A. We present a rare case of pulmonary artery intramural hematoma associated with a Stanford type B aortic dissection in an 85-year-old man. ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2015.05.004
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The present study aimed to assess the reliability and reproducibility of coronary computed tomography angiography (CCTA) for the serial quantitative assessment of plaque volume. METHODS:Patients who underwent repeated CCTA scans within 90 days were retrospectively screened and enrolled. Clinical data and CC...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2018.09.012
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Sudden cardiac death is the leading cause of death among firefighters in the United States. Fire departments commonly maintain physical examination protocols, often with exercise stress testing, to detect risk of coronary heart disease. OBJECTIVE:We sought to determine whether coronary calcium detected by e...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2012.07.003
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Among CT scanners, 320-row instruments feature decreased photon energy and yield strong contrast enhancement. Consequently, the contrast medium (CM) dose can be reduced. The results of low-tube-voltage coronary CT angiography (CCTA) performed on 320-row scanners have not been adequately assessed. OBJECTIVE:...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcct.2014.12.002
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:While an assessment of the right ventricular (RV) size remains challenging, the entire RV is can be imaged on coronary computed tomography angiography (CCTA) studies. With prospective ECG-triggering, the RV end diastolic volume (RVEDV) cannot be measured; however, the RV mid-diastolic volume (RVMDV) can stil...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2019.11.003
更新日期:2020-01-01 00:00:00
abstract::Myocardial bridging describes the clinical entity whereby a segment of coronary artery is either partially or completely covered by surrounding myocardium. It represents the most frequent congenital coronary anomaly and has an estimated prevalence of ≤13% on angiographic series. With the emergence of cardiac computed ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jcct.2011.10.015
更新日期:2012-01-01 00:00:00
abstract::Clinical trials assessing the effect of medical therapies on atherosclerotic plaques have hitherto employed invasive imaging techniques such as intravascular ultrasound (IVUS). This has limited the study population to high-risk patients in whom invasive coronary angiography is indicated; moreover, IVUS typically is pe...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章,评审
doi:10.1016/j.jcct.2019.06.017
更新日期:2019-01-01 00:00:00
abstract::A 37-year-old man who recently underwent aortic valve replacement after endocarditis presented with cardiogenic shock. A large expansile pseudoaneurysm was subsequently discovered using multiple imaging modalities. Although transesophageal echocardiography is important in diagnosing valve endocarditis, coronary CT ang...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2014.12.003
更新日期:2015-05-01 00:00:00
abstract::An 82-year-old patient developed right heart failure in the days after surgical aortic valve replacement. Coronary CT angiography showed a high-grade stenosis of the mid-right coronary artery. Adjacent suture material seen on noncontrast CT suggested that the lesion was related to surgical closure of the right atrial ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2010.01.005
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Myocardial fibrosis (MF) occurs in up to 80% of subjects with asymptomatic or mildly symptomatic hypertrophic cardiomyopathy (HCM) and can constitute an arrhythmogenic substrate for re-entrant, life-threatening ventricular arrhythmias in predisposed persons. OBJECTIVE:The aim was to investigate whether MF d...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2013.04.002
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Computed tomography is the best noninvasive imaging modality for evaluating valve leaflet calcification. OBJECTIVE:To evaluate the association of aortic valve leaflet calcification with instantaneous valve opening and closing using dynamic multidetector computed tomography (MDCT). METHODS:We retrospectivel...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2016.08.006
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Obesity is a risk factor for coronary artery disease (CAD), but adiposity may mimic symptoms of CAD and reduce the accuracy of diagnostic testing. METHODS:Patients from the PROMISE trial (n = 8889) were classified according to body mass index (BMI). We assessed relationships between BMI, physician's prefere...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2019.03.010
更新日期:2019-01-01 00:00:00
abstract::Cardiac CT offers several approaches to establish the hemodynamic severity of coronary artery obstructions. Dynamic myocardial perfusion CT (MPICT) is based on serial CT imaging to measure the inflow of contrast medium into the myocardium and calculate absolute measures of myocardial perfusion. This review describes t...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章,评审
doi:10.1016/j.jcct.2019.09.003
更新日期:2020-01-01 00:00:00
abstract::We present a case of a primary cardiac B-cell lymphoma where a multiphase-gated cardiac CT exam helped to successfully guide trans-sternal needle biopsy to establish a tissue diagnosis. ...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2011.12.007
更新日期:2012-03-01 00:00:00
abstract:AIMS:Fractional flow reserve (FFR) pullback allows to assess the distribution of pressure loss along the coronary vessels. FFR derived from CT (FFRCT) provides a virtual pullback curve that may also aid in the assessment of the distribution of epicardial coronary resistance in the non-invasive setting. The present stud...
journal_title:Journal of cardiovascular computed tomography
pub_type: 杂志文章
doi:10.1016/j.jcct.2019.09.004
更新日期:2020-01-01 00:00:00