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Coronary calcium scoring from contrast coronary CT angiography using a semiautomated standardized method.

Abstract：

BACKGROUND:When coronary calcium scoring is performed in patients with suspected coronary artery disease, a separate noncontrast scan is acquired before contrast-enhanced coronary CT angiography (CTA). OBJECTIVE:Our aim was to develop and validate an automated method for calculating the coronary calcium score (CCS) from coronary CTA. METHODS:We analyzed coronary CTA and noncontrast CT data sets of 84 patients (Agatston score >0). The CCS on noncontrast CT was measured using commercial methods. Coronary calcium volume was measured on coronary CTA using an automated standardized method with scan-specific calcium thresholds. Data sets were split into derivation (n = 40) and validation groups (n = 44). To calculate the CCS on coronary CTA, a conversion factor between calcium scores measured in noncontrast CT and the calcium volume measured on coronary CTA was derived by linear regression. RESULTS:In the validation group, the median calculated CCS derived from CTA was 277 and 244 on noncontrast images (P = .12). This CCS showed an excellent correlation with the CCS from noncontrast images (Pearson, r = 0.95). In the validation group, 39 of 44 patients (88.6%) were classified into the same standard category (1-10, 11-100, 101-400, or >400) with an excellent agreement (weighted κ of 0.87). CONCLUSION:CCSs can be accurately measured from contrast-enhanced coronary CTA by using an automated, standardized method, obviating the need for a noncontrast scan.

journal_name

J Cardiovasc Comput Tomogr

journal_title

Journal of cardiovascular computed tomography

authors

Schuhbaeck A,Otaki Y,Achenbach S,Schneider C,Slomka P,Berman DS,Dey D

doi

10.1016/j.jcct.2015.06.001

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

446-53

issue

5

eissn

1934-5925

issn

1876-861X

pii

S1934-5925(15)00203-8

journal_volume

9

pub_type

杂志文章,多中心研究

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