Abstract:
OBJECTIVE:Determination of coronary artery calcium scoring (CACS) in non-contrast computed tomography (CT) images has been shown to be an important prognostic factor in coronary artery disease (CAD). The objective of this study was to evaluate the accuracy of CACS from virtual non-contrast (VNC) imaging generated from spectral data in comparison to standard (true) non-contrast (TNC) imaging in a representative patient cohort with clinically approved software. METHODS:One hundred three patients referred to coronary CTA with suspicion of CAD were investigated on a dual-layer spectral detector CT (SDCT) scanner. CACS was calculated from both TNC and VNC images by software certified for medical use. Patients with a CACS of 0 were excluded from analysis. RESULTS:The mean age of the study population was 61 ± 11 years with 48 male patients (67%). Inter-quartile range of clinical CACS was 22-282. Correlation of measured CACS from true- and VNC images was high (0.95); p < 0.001. The slope was 3.83, indicating an underestimation of VNC CACS compared to TNC CACS by that factor. Visual analysis of the Bland-Altman plot of CACS showed good accordance with both methods after correction of VNC CACS by the abovementioned factor. CONCLUSIONS:In clinical diagnostics of CAD, the determination of CACS is feasible using VNC images generated from spectral data obtained on a dual-layer spectral detector CT. When multiplied by a correction factor, results were in good agreement with the standard technique. This could enable radiation dose reductions by obviating the need for native scans typically used for CACS. KEY POINTS:• Calcium scoring is feasible from contrast-enhanced CT images using a dual-layer spectral detector CT scanner. • When multiplied by a correction factor, calcium scoring from virtual non-contrast images shows good agreement with the standard technique. • Omitting native scans for calcium scoring could enable radiation dose reduction.
journal_name
Eur Radioljournal_title
European radiologyauthors
Gassert FG,Schacky CE,Müller-Leisse C,Gassert FT,Pahn G,Laugwitz KL,Makowski MR,Nadjiri Jdoi
10.1007/s00330-020-07677-wsubject
Has Abstractpub_date
2021-01-20 00:00:00eissn
0938-7994issn
1432-1084pii
10.1007/s00330-020-07677-wpub_type
杂志文章abstract::The majority of abnormal findings or lesions on T2-weighted fast spin-echo (FSE) magnetic resonance imaging (MRI) are hyperintense due to increased perfusion or fluid content, such as infections, tumours or synovitis. Hypointense lesions on T2-weighted images (both fat-suppressed and non-fat-suppressed) are less commo...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-015-4027-2
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:To establish the role of unenhanced CT in predicting the outcome of liver hydatid cysts. We sought to determine whether the presence of laminated membrane detachment (LMD) or pericyst degenerative changes (PDCs) detected on CT were reliable signs for predicting a favorable outcome of liver hydatids. METHODS...
journal_title:European radiology
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abstract::The goal of this study was 3-month clinical outcome in nonanticoagulated patients with clinically suspected acute pulmonary embolism (PE) following a negative spiral CT. During a 6-month period 305 patients underwent spiral CT, of whom only 8 also had a lung scintigraphy. In patients with a final CT report read as not...
journal_title:European radiology
pub_type: 杂志文章
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abstract:OBJECTIVES:To develop a non-invasive MRI method for evaluation of liver fibrosis, with histological analysis as the reference standard. METHODS:The study protocol was approved by the Institutional Review Board for Human Studies of our hospital, and written informed consent was obtained from all subjects. Seventy-nine ...
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doi:10.1007/s00330-005-2778-x
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2020-09-21 00:00:00
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journal_title:European radiology
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journal_title:European radiology
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