Disorders of the perceptual-motor system.

Abstract:

:The study of patients with movement disorders provides insight into both the functional organization and the neural substrates of the perceptual-motor system. By and large, we feel this source of information has been underutilized within the basic science of motor control. To begin to address this shortcoming, this chapter reviews three disorders of the perceptual-motor system (disorders of the body schema, optic ataxia, and ideomotor apraxia) and illustrates how the study of these disorders can inform central issues within the field of motor control. These issues include (1) the need for the perceptual-motor system to maintain a representation of the body's current configuration in order to produce movements, (2) the use of visual information in movement production, (3) the coordinate frame in which movements are controlled, (4) the distinction between movement planning and online correction, and (5) the role of the parietal cortex in action. In the conclusion, we discuss several limitations of studying patients with movement disorders as well as suggest that greater communication is needed between researchers in the basic science of motor control and clinicians developing treatments for movement disorders.

journal_name

Adv Exp Med Biol

authors

Jax SA,Coslett HB

doi

10.1007/978-0-387-77064-2_19

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

377-91

eissn

0065-2598

issn

2214-8019

journal_volume

629

pub_type

杂志文章,评审
  • Tumor oxygen dynamics: comparison of 19F MR EPI and frequency domain NIR spectroscopy.

    abstract::Oxygen plays a key role in tumor therapy and may be related to tumor development: e.g., angiogenesis and metastasis. Using noninvasive techniques to accurately measure tumor oxygenation could assist in developing novel therapies. Here, we have used the FREDOM (Fluorocarbon Relaxometry using Echo planar imaging for Dyn...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-0075-9_22

    authors: Song Y,Worden KL,Jiang X,Zhao D,Constantinescu A,Liu H,Mason RP

    更新日期:2003-01-01 00:00:00

  • Heterogeneity of Stem Cells in the Thyroid.

    abstract::Identification of thyroid stem cells in the past few years has made important contributions to our understanding of the cellular and molecular mechanisms that induce tissue regeneration and repair. Embryonic stem (ES) cells and induced-pluripotent stem cells have been used to establish reliable protocols to obtain mat...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-24108-7_5

    authors: Zito G,Coppola A,Pizzolanti G,Giordano C

    更新日期:2019-01-01 00:00:00

  • Some reflections on intermittent hypoxia. Does it constitute the translational niche for carotid body chemoreceptor researchers?

    abstract::The views presented in this article are the fruit of reflections and discussion with my colleagues at Valladolid and with the members of the Sleep Apnea Hypopnea Syndrome Group of the CIBERES (Spain). We have assembled the article in three sections. In the first one we provide a mechanistic description of obstructive ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-94-007-4584-1_45

    authors: Gonzalez C,Yubero S,Gomez-Niño MA,Agapito T,Rocher A,Rigual R,Obeso A,Montserrat JM

    更新日期:2012-01-01 00:00:00

  • Thiolation and disulphide cross-linking of insulin to form macromolecules of potential therapeutic value.

    abstract::Macromolecules have been prepared containing native insulin carried by a modified insulin skeleton made by partially thiolating the insulin hexamer and forming intermolecular cross-links through disulphide bridges. Oxidation of partially thiolated insulin (0.5-0.7 SH group/mole), formed by reacting insulin with AHTL, ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-3282-4_15

    authors: Mahbouba M,Smith HJ

    更新日期:1977-01-01 00:00:00

  • Neonicotinoid insecticides: historical evolution and resistance mechanisms.

    abstract::The use ofneonicotinoid insecticides has grown considerably since their introduction in 1990s. They are used extensively for the control of agriculturally important crop pests and also in the control of cat and dog fleas. Imidacloprid exploited through an elaborated structural and substituent optimization of nithiazin...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:

    authors: Thany SH

    更新日期:2010-01-01 00:00:00

  • The ovalbumin gene: transcriptional regulation by estrogen.

    abstract::De novo synthesis of RNA sequences corresponding to intervening as well as to structural sequences of the ovalbumin gene have been detected in isolated oviduct nuclei. Their presence in the nuclear transcripts and their time course of induction support the hypothesis that transcription of structural and intervening se...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-6589-2_25

    authors: Swaneck GE,Tsai SY,Tsai MJ,Nordstrom JL,Roop DR,O'Malley BW

    更新日期:1979-01-01 00:00:00

  • The role of ion channels in hypoxic pulmonary vasoconstriction.

    abstract::Hypoxic pulmonary vasoconstriction (HPV) is an important mechanism by which localized flow of blood in small resistance pulmonary arteries is matched to alveolar ventilation. This chapter discusses the role of several potassium and calcium channels in HPV, both in enhancing calcium influx into smooth muscle cells (SMC...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-60761-500-2_1

    authors: Weir EK,Cabrera JA,Mahapatra S,Peterson DA,Hong Z

    更新日期:2010-01-01 00:00:00

  • Molecular events in the assembly of retrovirus particles.

    abstract::Retrovirus assembly results from the ability of a single gene product, the gag polyprotein precursor, to coalesce into a spherical particle capable of release from the cell. In conjunction with this primary process of capsid formation additional viral gene products such as the replicative enzymes and envelope glycopro...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-5331-1_43

    authors: Sakalian M,Hunter E

    更新日期:1998-01-01 00:00:00

  • Comparative genome analyses of the pathogenic Yersiniae based on the genome sequence of Yersinia enterocolitica strain 8081.

    abstract::This chapter represents a summary of the findings from the Yersinia enterocolitica strain 8081 whole genome sequence and the associated microarray analysis. Section 1 & 2 provide an introduction to the species and an overview of the general features of the genome. Section 3 identifies important regions within the geno...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-0-387-72124-8_1

    authors: Thomson NR,Howard S,Wren BW,Prentice MB

    更新日期:2007-01-01 00:00:00

  • EPR spectroscopy and imaging of oxygen: applications to the gastrointestinal tract.

    abstract::EPR imaging has emerged as an important tool for noninvasive three-dimensional (3D) spatial mapping of free radicals in biological tissues. Spectral-spatial EPR imaging enables mapping of the spectral information at each spatial position, and, from the observed linewidth, the localized tissue oxygenation can be mapped...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-0075-9_12

    authors: Zweier JL,He G,Samouilov A,Kuppusamy P

    更新日期:2003-01-01 00:00:00

  • B cell receptor and antigens in CLL.

    abstract::Nowadays, chronic lymphocytic leukemia (CLL) is considered as a prototypic antigen-driven lymphoma, with antigenic stimuli from the microenvironment promoting tumor outgrowth. Antigen recognition is a function of both the clonotypic B cell receptor immunoglobulin (BcR IG) and various other immune sensors, e.g., the To...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-8051-8_1

    authors: Agathangelidis A,Ntoufa S,Stamatopoulos K

    更新日期:2013-01-01 00:00:00

  • Iron in the Tumor Microenvironment.

    abstract::Cancer metabolism is a well-known target of cancer therapeutics. Classically, cancer metabolism has been studied in terms of the dependence of cancer cells on crucial metabolites, such as glucose and glutamine. But, the accumulating data show that iron metabolism in tumor microenvironment is also an important factor i...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-43093-1_3

    authors: Vela D

    更新日期:2020-01-01 00:00:00

  • The importance of case reports in advancing scientific knowledge of rare diseases.

    abstract::Case reports are defined as the scientific documentation of a single clinical observation and have a time-honored and rich tradition in medicine and scientific publication. Case reports represent a relevant, timely, and important study design in advancing medical scientific knowledge especially of rare diseases. While...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-90-481-9485-8_5

    authors: Carey JC

    更新日期:2010-01-01 00:00:00

  • Lectin receptors and lectin resistance in chinese hamster ovary cells.

    abstract::Chinese hamster ovary (CHO) cells previously selected in a single-step for resistance to one or two different lectins and assigned to individual phenotypic groups on the basis of their unique patterns of lectin resistance, have been examined for their lectin-binding abilites. The lectin-binding parameters of CHO cells...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-3279-4_13

    authors: Stanley P,Carver JP

    更新日期:1977-01-01 00:00:00

  • Erythrocytes as carriers of new anti-opioid prodrugs: in vitro studies.

    abstract::In using a reversed hypoosmotic lysis and resealing process, internalization of Naloxone or Naltrexone prodrugs as new opioid antagonists into red blood cells (RBC) can be obtained. We describe the entrapment method and haematological parameters of such RBC carriers. Percentages of internalization range between 35% an...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-3030-5_27

    authors: Noël-Hocquet S,Jabbouri S,Lazar S,Maunier JC,Guillaumet G,Ropars C

    更新日期:1992-01-01 00:00:00

  • Converting enzyme, kininase and angiotensinase of renal and intestinal brush border.

    abstract::Kinins and angiotensins affect renal and intestinal function and are rapidly converted and/or inactivated in the renal proximal tubule and intestinal tract by converting enzyme, kininases and angiotensinases of the brush border. Converting enzyme accounts for only 40% of intestinal kininases activity. Thus inhibition ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:

    authors: Ward PE,Sheridan MS

    更新日期:1983-01-01 00:00:00

  • Effect of age on kidney hyperplasia in the rat after unilateral nephrectomy.

    abstract::The absolute weight of the rat's kidney increases from 3 weeks to 3 months and from 3 months to 12 months. The relative weight decreases. The number of cells freed from the kidney by trypsinization increases. (2) After nephrectomy, the kidney weight increases in all age groups. The increase is mery high in the younges...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-0731-1_24

    authors: Soukupová M,Hnĕvkovský P,Najbrt J

    更新日期:1975-01-01 00:00:00

  • Computational Modeling of Collective Cell Migration: Mechanical and Biochemical Aspects.

    abstract::Collective cell migration plays key roles in various physiological and pathological processes in multicellular organisms, including embryonic development, wound healing, and formation of cancer metastases. Such collective migration involves complex crosstalk among cells and their environment at both biochemical and me...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-17593-1_1

    authors: Yang Y,Jolly MK,Levine H

    更新日期:2019-01-01 00:00:00

  • Herb Hultgren in Peru: what causes high altitude pulmonary edema?

    abstract::Herbert Hultgren, a cardiologist who kept a careful diary all his career, arrived in Peru at the beginning of 1959 to study the occurrence of pulmonary hypertension in children at high altitude with patent ductus arteriosus. There, he was told about a strange condition, high altitude pulmonary edema (HAPE), and found ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/978-1-4615-4711-2_1

    authors: Rennie D

    更新日期:1999-01-01 00:00:00

  • Systemic Treatments in Pregnancy-Associated Breast Cancer.

    abstract::Available data on systemic treatments in pregnancy-associated breast cancer (PABC) is reviewed in this section. These treatments include chemotherapy, endocrine therapy (ET), small molecule inhibitors, monoclonal antibodies against human epidermal growth factor receptor 2 (EGFR-2) also known as HER2; and human epiderm...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-41596-9_15

    authors: Tehrani OS

    更新日期:2020-01-01 00:00:00

  • Fructose Consumption and Lipid Metabolism in Obese Children and Adolescents.

    abstract::Inappropriate dietary habits influence the development of excessive body weight. The role of added sugars, including fructose, notably is significant in this process. It is estimated that fructose intake has increased many times over the past two centuries. The aim of the study was to define the effect of fructose con...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2018_330

    authors: Czerwonogrodzka-Senczyna A,Rumińska M,Majcher A,Credo D,Jeznach-Steinhagen A,Pyrżak B

    更新日期:2019-01-01 00:00:00

  • Syndromic Gastric Polyps: At the Crossroads of Genetic and Environmental Cancer Predisposition.

    abstract::Gastric polyps occur in 1-4 % of patients undergoing gastroscopy. Although most are sporadic, some gastric polyps are part of an underlying hereditary syndrome. Gastric polyps can be seen in each of the well-known gastrointestinal polyposis syndromes, but also in Lynch syndrome and in several rare not primarily gastro...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-41388-4_17

    authors: Brosens LA,Giardiello FM,Offerhaus GJ,Montgomery EA

    更新日期:2016-01-01 00:00:00

  • Normative Retinal Thicknesses in Common Animal Models of Eye Disease Using Spectral Domain Optical Coherence Tomography.

    abstract::Purpose This study demonstrates a standardized approach to measuring retinal thickness (RT) using spectral domain optical coherence tomography (SD-OCT) in commonly used animal models of disease and reports a normative data set for future use. Materials and Methods Twenty normal eyes of 4 adult animal models (5 rats, 5...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-75402-4_20

    authors: Carpenter CL,Kim AY,Kashani AH

    更新日期:2018-01-01 00:00:00

  • A method to study induction of autoimmunity in vitro: co-culture of lacrimal cells and autologous immune system cells.

    abstract::Co-culturing autologous lacrimal gland cells and immune system cells can lead to spleen cell proliferation with a time course similar to that for proliferation in a typical heterologous MLR. Although these results are consistent with the hypothesis that lacrimal acinar cells are a source of antigen, and may or may not...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-5359-5_82

    authors: Kaslow HR,Guo Z,Warren DW,Wood RL,Mircheff AK

    更新日期:1998-01-01 00:00:00

  • Exosomes for immunotherapy of cancer.

    abstract::Exosomes are 60 to 90 nm membrane vesicles originating from late endosomes and secreted from most hematopoietic and epithelial cells in vitro. B cell derived-exosome antigenicity was first reported in 1996 in MHC class II restricted CD4+ T lymphocytes. In 1998, we reported that dendritic cell derived-exosomes are immu...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-0081-0_17

    authors: Chaput N,Schartz NE,Andre F,Zitvogel L

    更新日期:2003-01-01 00:00:00

  • Clinical Evidence of Exercise Benefits for Stroke.

    abstract::Even though stroke is the third, not the first, most common cause of disability-adjusted life years in developed countries, it is one of the most expensive to treat. Part of the expense is due to secondary problems in the post-stroke period including: cognition, memory, attention span, pain, sensation loss, psychologi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-981-10-4304-8_9

    authors: Han P,Zhang W,Kang L,Ma Y,Fu L,Jia L,Yu H,Chen X,Hou L,Wang L,Yu X,Kohzuki M,Guo Q

    更新日期:2017-01-01 00:00:00

  • Constituents of Cannabis Sativa.

    abstract::The Cannabis sativa plant has been used medicinally and recreationally for thousands of years, but recently only relatively some of its constituents have been identified. There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including Δ9-tetrahydrocannabinol (TH...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-57369-0_1

    authors: Rock EM,Parker LA

    更新日期:2021-01-01 00:00:00

  • Oviducal pars recta as factor in fertilization properties and hormonal regulation in the toad Bufo arenarum.

    abstract::In this communication I have attempted to present an overview of some contributions to the understanding of the oviduct-egg interaction in amphibians. According to data from other authors, the vitelline envelope of the newly ovulated egg constitutes a barrier for the passage of spermatozoa. Our results demonstrated th...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4613-2255-9_11

    authors: Miceli DC

    更新日期:1986-01-01 00:00:00

  • Usher syndrome protein network functions in the retina and their relation to other retinal ciliopathies.

    abstract::The human Usher syndrome (USH) is the most frequent cause of combined hereditary deaf-blindness. USH is genetically and clinically heterogeneous: 15 chromosomal loci assigned to 3 clinical types, USH1-3. All USH1 and 2 proteins are organized into protein networks by the scaffold proteins harmonin (USH1C), whirlin (USH...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-3209-8_67

    authors: Sorusch N,Wunderlich K,Bauss K,Nagel-Wolfrum K,Wolfrum U

    更新日期:2014-01-01 00:00:00

  • Ontogeny of the mucosal immune response in children.

    abstract::The development of secretory IgA was followed in saliva of 263 children from birth to age 5, and in cross sectional studies of Australian school children and Papua New Guinea highland children from birth to age 5. Salivary IgA first appeared after the first week of life, peaking at 6 weeks, and falling again at 12 wee...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-3838-7_9

    authors: Cripps AW,Gleeson M,Clancy RL

    更新日期:1991-01-01 00:00:00