Ovulation inhibition by a new low-dose progestagen.

abstract：:The importance of a simple, rapid and highly sensitive test for the diagnosis of early pregnancy cannot be overemphasized. In the present times when newer delivery systems of contraceptive agents and menstrual regulation procedures are increasingly used for fertility regulation, it is inevitable that confirmation of e...

journal_title：Contraception

authors： Shahani SM,Kulkarni PP,Patel KL

更新日期：1978-11-01 00:00:00

abstract：:The exact role of apoptosis that occurs in human placenta during the early stage of pregnancy remains unknown because of the difficulty in obtaining the intact implantation site. In this study, we used rhesus monkey as an animal model to examine apoptosis occurring in the implantation site at various stages of early p...

journal_title：Contraception

authors： Fei G,Peng W,Xin-Lei C,Zhao-Yuan H,Yi-Xun L

更新日期：2001-09-01 00:00:00

abstract：:A method based on HPLC was devised for the estimation of RU 486 in blood and utilised to study the pharmacokinetics of a single dose of 50 mg RU 486 administered orally to 12 women on day 7 of the cycle. The dose was rapidly absorbed with peak plasma concentration between 1 and 2 hours. Distribution was also rapid (me...

journal_title：Contraception

authors： He CH,Shi YE,Ye ZH,Zhang GG,Jiang NX,Van Look PF,Fotherby K

更新日期：1989-10-01 00:00:00

abstract：:Plasma concentrations of levonorgestrel, progesterone, estradiol, FSH and LH were measured in seven volunteers who had a levonorgestrel-releasing IUD inserted postmenstrually. Blood samples were collected twice weekly during a mean of 93 days immediately postmenstrually and during a mean of 41 days over the twelfth to...

journal_title：Contraception

authors： Nilsson CG,Lähteenmäki P,Luukkainen T

更新日期：1980-03-01 00:00:00

abstract：INTRODUCTION:The relationship between the source of sexual information and adolescent sexual behavior is not well understood. MATERIALS AND METHODS:As part of a larger study, 892 sexually active female adolescents between 15 and 18 years of age completed a paper-and-pencil survey which assessed discussions about sexua...

journal_title：Contraception

authors： Berenson AB,Wu ZH,Breitkopf CR,Newman J

更新日期：2006-03-01 00:00:00

abstract：:Written guidelines for the preclinical testing of contraceptive steroids have not been revised since 1968 despite the fact that many important changes have been implemented by the FDA's Division of Metabolism and Endocrine Drug Products. This paper describes the new preclinical testing requirements and the rationale f...

journal_title：Contraception

authors： Jordan A

更新日期：1992-12-01 00:00:00

abstract：:Increased menstrual blood loss (MBL) associated with intrauterine device (IUD) use may precipitate or aggravate iron deficiency anaemia, adversely affecting the health of women particularly those from developing countries. Studies were conducted to define the association of MBL and iron status in South American women;...

journal_title：Contraception

authors： Andrade AT,Pizarro E,Shaw ST Jr,Souza JP,Belsey EM,Rowe PJ

更新日期：1988-07-01 00:00:00

abstract：:Detailed information was collected from 666 cohorts of pill, injectable-DMPA and IUD acceptors at 14 Bangkok Metropolis Health Clinics (MHCs). The contraceptive status at 12-month follow-up home interview shows that 47% of pill acceptors, 39% of DMPA acceptors and 55% of IUD acceptors were still using the same contrac...

journal_title：Contraception

authors： Chumnijarakij T,Sunyavivat S,Onthuam Y,Udomprasertgul V

更新日期：1984-03-01 00:00:00

abstract：:As research has shown that knowledge concerning the health risks and benefits of oral contraceptive (OC) use is a contributor to OC compliance, the following study examined an educated sample of young women to determine the level of knowledge concerning the risks and benefits of OC use. A 28-item questionnaire was dev...

journal_title：Contraception

authors： Bryden PJ,Fletcher P

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Transdermal delivery of steroids is gaining popularity for contraception and hormone replacement therapy. This study aimed to test metered spray delivery of a precise dosage of Nestorone (NES) progestogen as a possible transdermal progestogen-only contraceptive. STUDY DESIGN:Six healthy postmenopausal volun...

journal_title：Contraception

authors： Fraser IS,Weisberg E,Kumar N,Kumar S,Humberstone AJ,McCrossin L,Shaw D,Tsong YY,Sitruk-Ware R

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Including support staff in practice change initiatives is a promising strategy to successfully implement new reproductive health services. The Resident Training Initiative in Miscarriage Management (RTI-MM) is an intervention designed to facilitate implementation of manual vacuum aspiration (MVA) for managem...

journal_title：Contraception

authors： Darney BG,VanDerhei D,Weaver MR,Stevens NG,Prager SW

更新日期：2013-08-01 00:00:00

abstract：:The study reported herein is the primary efficacy and safety study conducted to support U.S. registration of an oral contraceptive containing 150 micrograms desogestrel and 30 micrograms ethinyl estradiol. A large multicenter study enrolled 1,221 women at 50 centers in the United Kingdom. A total of 11,656 cycles of e...

journal_title：Contraception

authors： Walling M

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:To measure the 24-month impact on continuation, unintended pregnancy and satisfaction of trying long-acting reversible contraception (LARC) in a population seeking short-acting reversible contraception (SARC). STUDY DESIGN:We enrolled 916 women aged 18-29 who were seeking pills or injectables in a partially...

journal_title：Contraception

authors： Hubacher D,Spector H,Monteith C,Chen PL

更新日期：2018-06-01 00:00:00

abstract：:Test agents were selected because of previous evidence of contragestationaal activity when administered systemically or because of known local effects which would be likely to cause endometrial changes having an adverse effect on pregnancy. A group of virgin female Sprague-Dawley rats were treated on Day 3 of pregnan...

journal_title：Contraception

authors： Conner EA,Blake DA,Parmley TH,Burnett LS,King TM

更新日期：1976-05-01 00:00:00

abstract：OBJECTIVE:To assess the cost-effectiveness of self-injected subcutaneous depot medroxyprogesterone acetate (DMPA-SC) compared to health-worker-administered intramuscular DMPA (DMPA-IM) in Uganda. STUDY DESIGN:We developed a decision-tree model with a 12-month time horizon for a hypothetical cohort of approximately 1 m...

journal_title：Contraception

authors： Di Giorgio L,Mvundura M,Tumusiime J,Morozoff C,Cover J,Drake JK

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The gold standard for measuring oral contraceptive (OC) pharmacokinetics is the 24-h steady-state area under the curve (AUC). We conducted this study to assess whether limited sampling at steady state or measurements following use of one or two OCs could provide an adequate proxy in epidemiological studies fo...

journal_title：Contraception

authors： Basaraba CN,Westhoff CL,Pike MC,Nandakumar R,Cremers S

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:To assess factors associated with routine pregnancy intention screening by primary care physicians and their support for such an initiative. STUDY DESIGN:We conducted a cross-sectional survey study of 443 primary care physicians in New York State. We performed multivariable logistic regression analyses of p...

journal_title：Contraception

authors： Manze MG,Calixte C,Romero DR,Roberts L,Perlman M,Langston A,Jones HE

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:We sought to assess fulfillment of sterilization requests while accounting for the complex interplay between insurance, clinical and social factors in a contemporary context that included both inpatient and outpatient postpartum sterilization procedures. STUDY DESIGN:This is a retrospective single-center coh...

journal_title：Contraception

authors： Arora KS,Wilkinson B,Verbus E,Montague M,Morris J,Ascha M,Mercer BM

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of a scholarly concentration for medical students, which aims to develop students' research, clinical and advocacy skills to promote women's reproductive health. STUDY DESIGN:Scholarly concentration programs provide opportunities to engage in scholarship beyond the traditional medical...

journal_title：Contraception

authors： Nothnagle M,Radlinski H,Magee SR,Allen RH

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To determine if laparoscopic sterilization using the Filshie clip causes less postoperative pain as compared to the Falope ring during the first 24 h after surgery. STUDY DESIGN:Forty subjects were enrolled. Five milliliters of 0.5% bupivicaine was injected at each of the two incision sites and 5 mL was drip...

journal_title：Contraception

authors： Pymar HC,Creinin MD,Vallejo MC

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Determining medical abortion outcome commonly includes a costly evaluation such as ultrasonography or serial serum hCG testing. Urine pregnancy testing may represent a less costly alternative. METHODS:This prospective diagnostic test evaluation study was part of a multisite randomized trial of 1080 women un...

journal_title：Contraception

authors： Godfrey EM,Anderson A,Fielding SL,Meyn L,Creinin MD

更新日期：2007-05-01 00:00:00

abstract：:This paper presents a secondary analysis of 3419 Norplant users from 11 countries throughout Asia, Africa and Latin America. The main objective was to identify the menstrual problems associated with a high risk of early discontinuation of Norplant use. Eligible participants were divided into two groups: those who cont...

journal_title：Contraception

authors： Rivera R,Rountree W

更新日期：2003-05-01 00:00:00

abstract：:The clinical performance of two levonorgestrel-releasing intrauterine devices (IUDs) with different release rates was studied and compared with a copper-releasing Nova-T device in a randomized partly double-blind multiclinical trial. Special attention was given to patterns of bleeding, hormonal side-effects, blood pre...

journal_title：Contraception

authors： Nilsson CG,Luukkainen T,Diaz J,Allonen H

更新日期：1982-04-01 00:00:00

abstract：:The use of mifepristone as an anti-implantation agent in the primate has been explored in the rhesus monkey with two specific aims: (i) to determine the contraceptive efficacy of very low-dose mifepristone administered on mated cycle days 16, 17, and 18; and (ii) to test the hypothesis that alteration in endometrial p...

journal_title：Contraception

authors： Nayak NR,Ghosh D,Lasley BL,Sengupta J

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Between 2006 and 2008, Iowa increased access to family planning services through a Medicaid expansion and a privately funded initiative. During this same time, Iowa expanded access to abortion through telemedicine provision of medical abortion. Despite increased access to abortion services, abortions in Iowa...

journal_title：Contraception

authors： Biggs MA,Rocca CH,Brindis CD,Hirsch H,Grossman D

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Determine if erythromycin is an effective agent for achieving occlusion of the Fallopian tube for nonsurgical female sterilization. METHODS:Two studies of 100 healthy volunteers requesting sterilization were planned, one in Julpia Andhermanik and the other in Kolkata (Calcutta). A readily available marketed ...

journal_title：Contraception

authors： Bairagy NR,Mullick BC

更新日期：2004-01-01 00:00:00

abstract：:There is considerable variation in opinion about the importance of drug interactions between the combined oral contraceptive pill (COCP) and broad-spectrum antibiotics. Clinical practice varies widely, especially between doctors in Europe and those in the US. Rifampicin and griseofulvin induce hepatic enzymes and do a...

journal_title：Contraception

authors： Weaver K,Glasier A

更新日期：1999-02-01 00:00:00

abstract：:Intramuscular injection of 200 mg norethisterone enanthate (NET-EN) was given to five women on the day of first trimester abortion. The injection was repeated twice at eight-week intervals, and thereafter at twelve-week intervals for one year. Plasma samples were collected for FSH, LH/hCG, estradiol, progesterone and ...

journal_title：Contraception

authors： Lähteenmäki P,Toivonen J,Lähteenmäki PL

更新日期：1983-06-01 00:00:00

abstract：:Research has established the principle of hormonal male contraception based on suppression of gonadotropins and spermatogenesis. All hormonal male contraceptives use testosterone, but only in East Asian men can testosterone alone suppress spermatogenesis to a level compatible with contraceptive protection. In Caucasia...

journal_title：Contraception

authors： Nieschlag E

更新日期：2010-11-01 00:00:00

abstract：:A 28-year-old woman presented with a malpositioned intrauterine device (IUD) that was fragmented and significantly entrenched within the cervical canal and myometrium. IUD malposition with concomitant device fragmentation and embedded segments, albeit rare, should be a consideration given the device's prevalence. ...

journal_title：Contraception

authors： Korber PE,Goldstein BH

更新日期：2019-01-01 00:00:00