Early maternal deprivation in rats: a proposed animal model for the study of developmental neuroimmunoendocrine interactions.

abstract：:Moderated by Lisa Miller from Newsweek, evolutionary biologist Kenneth Miller (Brown University) and theologians John Haught (Georgetown University) and Nancey Murphy (Fuller Theological Seminary) discuss the questions Are we immortal? Do our souls exist beyond our bodies? and What scientific evidence is there for mys...

journal_title：Annals of the New York Academy of Sciences

authors： Miller L,Miller K,Haught J,Murphy N

更新日期：2011-10-01 00:00:00

abstract：:A remarkable "steroid sparing" effect of Saiboku-to was noted within 6 to 12 months of treatment in steroid-dependent asthmatic patients. Saiboku-to spared the downregulation of glucocorticoid receptor of human lymphocytes, plasma ACTH, and cortisol levels. It also spared downregulation of beta 2 receptor by beta 2 ag...

journal_title：Annals of the New York Academy of Sciences

authors： Nakajima S,Tohda Y,Ohkawa K,Chihara J,Nagasaka Y

更新日期：1993-06-23 00:00:00

abstract：:This review will focus on the free radical signaling mechanism of preconditioning. The results from our laboratory as well as studies from other laboratories suggest that reactive oxygen species function as second messenger during myocardial adaptation to ischemia. This review provides evidence for the first time that...

journal_title：Annals of the New York Academy of Sciences

authors： Das DK,Engelman RM,Maulik N

更新日期：1999-06-30 00:00:00

abstract：:Women are four to eight times more likely to be affected by fibromyalgia syndrome (FMS). A lack of cortisol, potentially due to an adrenocortical deficit is postulated in FMS. The cause of such adrenal insufficiency is unknown. It could be assumed that stress exposure during critical periods contributes to vulnerabili...

journal_title：Annals of the New York Academy of Sciences

authors： Klingmann PO,Kugler I,Steffke TS,Bellingrath S,Kudielka BM,Hellhammer DH

更新日期：2008-12-01 00:00:00

abstract：:The primary objective of this review is to suggest a major role of cytogenetic pathology in the genesis of both the neoplastic phenotype and the senescent phenotype of aging mammalian organisms. It is hypothesized that allelic variation at a number of genetic loci that have the potential to modulate various types of c...

journal_title：Annals of the New York Academy of Sciences

authors： Martin GM

更新日期：1991-01-01 00:00:00

abstract：:Liver cirrhosis is a condition in which overnutrition, edema, and undernutrition can coexist simultaneously, or successively, over a period of time, giving rise to alterations in body composition, as well as systemic and multiorgan manifestations. We undertook a cross-sectional study of body composition in 198 adult p...

journal_title：Annals of the New York Academy of Sciences

authors： Strauss BJ,Gibson PR,Stroud DB,Borovnicar DJ,Xiong DW,Keogh J

更新日期：2000-05-01 00:00:00

abstract：:The counterregulatory response to hypoglycemia is a complex and well-coordinated process. As blood glucose concentration declines, peripheral and central glucose sensors relay this information to central integrative centers to coordinate neuroendocrine, autonomic, and behavioral responses and avert the progression of ...

journal_title：Annals of the New York Academy of Sciences

authors： Tesfaye N,Seaquist ER

更新日期：2010-11-01 00:00:00

abstract：:It is known that red wines have antioxidant properties owing to the presence of polyphenols and hydroxycinnamates. It has been reported that these compounds are efficient scavengers of peroxynitrite (ONOO(-)). We assayed the ONOO(-)-scavenging activity of plant polyphenols, hydroxycinnamates, and red wines using a flu...

journal_title：Annals of the New York Academy of Sciences

authors： Valdez LB,Actis-Goretta L,Boveris A

更新日期：2002-05-01 00:00:00

abstract：:It is hypothesized that a phonemic processing deficit is a primary causal factor in the reading problems of many children with developmental dyslexia. An instructional model which emphasizes phonics instruction as a key in the treatment of children with reading disorders is presented. Procedures for the application of...

journal_title：Annals of the New York Academy of Sciences

authors： Richardson E

更新日期：1984-01-01 00:00:00

abstract：:The beta cell fate following immune-mediated damage depends on an intricate pattern of dozens of genes up- or downregulated in parallel and/or sequentially. We are utilizing microarray analysis to clarify the pattern of gene expression in primary rat beta cells exposed to the proapoptotic cytokines, IL-1beta and/or IF...

journal_title：Annals of the New York Academy of Sciences

authors： Eizirik DL,Kutlu B,Rasschaert J,Darville M,Cardozo AK

更新日期：2003-11-01 00:00:00

abstract：:We have demonstrated a far more widespread and selective ischemic cell damage than previously thought. In area CA3, a distinct subpopulation of interneurons, characterized by their spiny dendrites and their calretinin content, was selectively vulnerable in the absence of any other CA3 involvement. In the dentate hilus...

journal_title：Annals of the New York Academy of Sciences

authors： Hsu M,Sik A,Gallyas F,Horváth Z,Buzsáki G

更新日期：1994-11-14 00:00:00

abstract：:Proopiomelanocortin (POMC) and proenkephalin (PE) are synthesized at the endoplasmic reticulum and transported to the trans-Golgi network (TGN) where they are sorted and packaged into dense-core granules of the regulated secretory pathway (RSP). The mechanism of sorting POMC and PE to the RSP in neuroendocrine cells w...

journal_title：Annals of the New York Academy of Sciences

authors： Loh YP,Maldonado A,Zhang C,Tam WH,Cawley N

更新日期：2002-10-01 00:00:00

abstract：:This paper examines the frequency of CIND, the profile of early cognitive deficits in stroke patients, the differences in the profile of cognitive impairment in people with CIND and those with vascular dementia, and the MRI associations of CIND in older stroke patients. ...

journal_title：Annals of the New York Academy of Sciences

authors： Ballard C,Stephens S,McLaren A,Wesnes K,Kenny RA,Burton E,O'Brien J,Kalaria R

更新日期：2002-11-01 00:00:00

abstract：:Insulin-dependent diabetes mellitus (IDDM) is one of the most common chronic diseases. It is an autoimmune, polygenic disease, associated with several genes on different chromosomes. The most important gene is human leukocyte antigen (HLA), also known as major histocompatibility complex (MHC), which is located on chro...

journal_title：Annals of the New York Academy of Sciences

authors： Shtauvere-Brameus A,Ghaderi M,Rumba I,Sanjeevi CB

更新日期：2002-04-01 00:00:00

abstract：:Tick-borne pathogens in the genus Ehrlichia cause emerging zoonoses. Although laboratory mice are susceptible to Ehrlichia infections, many isolates do not cause clinical illness. In contrast, the Ixodes ovatus Ehrlichia-like agent (IOE) causes disease and immune responses in mice comparable to the human illness cause...

journal_title：Annals of the New York Academy of Sciences

authors： Munderloh UG,Silverman DJ,MacNamara KC,Ahlstrand GG,Chatterjee M,Winslow GM

更新日期：2009-05-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) is a 28-amino acid peptide that has several functions, including the regulation of water and electrolyte secretion, hormone and cytokine release, bronchodilitation, and neurogenesis. VIP effects are mediated by specific G-protein coupled receptors. Three distinct receptor subtypes, ...

journal_title：Annals of the New York Academy of Sciences

authors： Karacay B,O'Dorisio MS,Summers M,Bruce J

更新日期：2000-01-01 00:00:00

abstract：:Homogenate of 30 sarcoid lymph nodes was injected into the footpads of mice and 42% of the mice showed epitheloid-cell granulomas in the sites. However, the control lymph-node homogenates obtained from nonsarcoid patients also provoked similar granulomatous changes, although the positive rate was somewhat lower. In th...

journal_title：Annals of the New York Academy of Sciences

authors： Iwai K,Takahashi S

更新日期：1976-01-01 00:00:00

abstract：:It is believed that HDL exerts its anti-atherogenic effects through the process of delivering cholesterol from peripheral tissues back to the liver for removal from the body (i.e., reverse cholesterol transport). The metabolic life cycle of HDL lipid and apolipoproteins during reverse cholesterol transport involves bo...

journal_title：Annals of the New York Academy of Sciences

authors： Silver DL,Jiang XC,Arai T,Bruce C,Tall AR

更新日期：2000-05-01 00:00:00

abstract：:Neuropsychiatric disorders (i.e., mood disorders and schizophrenia) and inflammation are closely intertwined, and possibly powering each other in a bidirectional loop. Depression facilitates inflammatory reactions and inflammation promotes depression and other neuropsychiatric disorders. Patients with neuropsychiatric...

journal_title：Annals of the New York Academy of Sciences

authors： Bauer ME,Teixeira AL

更新日期：2019-02-01 00:00:00

abstract：:Estrogen synthesized in situ plays a more important role in breast cancer cell proliferation than does circulating estrogen. Aromatase is the enzyme that converts androgen to estrogen and is expressed at a higher level in breast cancer tissue than in surrounding noncancer tissue. A promising route of chemoprevention a...

journal_title：Annals of the New York Academy of Sciences

authors： Eng ET,Williams D,Mandava U,Kirma N,Tekmal RR,Chen S

更新日期：2002-06-01 00:00:00

abstract：:Corticosteroids have potent immunosuppressive and anti-inflammatory effects. Although corticosteroids are an important weapon in the clinical arsenal for treating inflammatory episodes, the mechanisms underlying the actions and regulation of endogenous corticosteroids remain obscure. In the late 1980s and early 1990s,...

journal_title：Annals of the New York Academy of Sciences

authors： Harbuz MS,Chover-Gonzalez AJ,Jessop DS

更新日期：2003-05-01 00:00:00

abstract：:Carboxyfullerenes, including two regioisomers C3 and D3, were investigated as antioxidants against iron-induced oxidative stress in vivo and in vitro. Both C3 and D3 dose-dependently inhibited autoxidation and iron-elevated lipid peroxidation in cortical homogenates. The antioxidative property of C3 was compared to Tr...

journal_title：Annals of the New York Academy of Sciences

authors： Lin AM,Luh TY,Chou CK,Ho LT

更新日期：1999-01-01 00:00:00

abstract：:Experimental data together with clinical studies have generated information about the association between sympathetic nervous system activity and immunity as measured by in vitro correlates of cellular immune function. In addition, studies on the in vivo role of central CRF in coordinating sympathetic outflow and modu...

journal_title：Annals of the New York Academy of Sciences

authors： Irwin M

更新日期：1993-10-29 00:00:00

abstract：:1. There are several endogenous ligands that bind to I-receptors of both the I1 and I2 subclass. These include: (a) classic CDS, a partially purified entity isolated by the criteria that it displaces binding ligands to alpha 2- and I-receptors; (b) immunoreactive (ir)-CDS, a moiety that binds to antibodies raised agai...

journal_title：Annals of the New York Academy of Sciences

authors： Reis DJ,Li G,Regunathan S

更新日期：1995-07-12 00:00:00

abstract：:The human endometrium is an extremely sensitive target for steroid hormones. During the menstrual cycle, this tissue undergoes dynamic changes that are reflected on the surface morphology of the epithelium and that can be followed by scanning electron microscopy. The morphologic changes peak at the midsecretory phase,...

journal_title：Annals of the New York Academy of Sciences

authors： Nikas G,Makrigiannakis A,Hovatta O,Jones HW Jr

更新日期：2000-01-01 00:00:00

abstract：:The acquisition of both speech and music uses general principles: learners extract statistical regularities present in the environment. Yet, individuals who suffer from congenital amusia (commonly called tone-deafness) have experienced lifelong difficulties in acquiring basic musical skills, while their language abili...

journal_title：Annals of the New York Academy of Sciences

authors： Peretz I,Saffran J,Schön D,Gosselin N

更新日期：2012-04-01 00:00:00

abstract：:Recent perceptual experiments with normal adult listeners show that phonetic information can readily be conveyed by sinewave replicas of speech signals. These tonal patterns are made of three sinusoids set equal in frequency and amplitude to the respective peaks of the first three formants of natural-speech utterances...

journal_title：Annals of the New York Academy of Sciences

authors： Remez RE,Rubin PE,Pisoni DB

更新日期：1983-01-01 00:00:00

abstract：:Decreased postural stability is observed in most astronauts immediately following spaceflight. Because ataxia may present postflight operational hazards, it is important to determine the incidence of postural instability immediately following landing and the dynamics of recovery of normal postural equilibrium control....

journal_title：Annals of the New York Academy of Sciences

authors： Paloski WH,Reschke MF,Black FO,Doxey DD,Harm DL

更新日期：1992-05-22 00:00:00

abstract：:Thymic pathology occurs in 80-90% of myasthenia gravis patients. Significant associations between different thymic alterations and clinical findings are discussed. To highlight peculiarities in thymoma-associated myasthenia gravis, we briefly review myasthenia gravis associated with thymic lymphofollicular hyperplasia...

journal_title：Annals of the New York Academy of Sciences

authors： Marx A,Müller-Hermelink HK,Ströbel P

更新日期：2003-09-01 00:00:00

abstract：:Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). SRC occurs during the first 4 years of disease evolution in more than 75% of the cases, almost exclusively in patients with diffuse SSc. Other risk factors, including preceding corticosteroid therapy, have been associated...

journal_title：Annals of the New York Academy of Sciences

authors： Teixeira L,Mahr A,Berezné A,Noël LH,Guillevin L,Mouthon L

更新日期：2007-06-01 00:00:00