Apoptotic effects of Tian-Long compound on endometrial adenocarcinoma cells in vitro.

abstract：:Renal cell carcinoma (RCC) represents over 80% of kidney cancer, and about 30% of the patients with RCC develop metastasis after the surgery. Invasion of basement membrane (BM) and extracellular matrix (ECM) is an essential event in tumor invasion and metastasis. Matrix metalloproteinases (MMPs), which digest the main...

journal_title：Medical molecular morphology

authors： Mikami S,Oya M,Mizuno R,Kosaka T,Katsube K,Okada Y

更新日期：2014-06-01 00:00:00

abstract：:IgG4-related disease has been recently described. This disease occurs in various anatomic locations including pancreas, biliary tract, liver, retroperitoneum, kidney, breast, lung, thyroid gland, prostate, salivary gland, lacrimal gland, and lymph node. In this article, we report the first case of IgG4-related disease...

journal_title：Medical molecular morphology

authors： Kuroda N,Nakamura S,Miyazaki K,Inoue K,Ohara M,Mizuno K,Sato Y,Yoshino T

更新日期：2009-12-01 00:00:00

abstract：:ArgBP2 is a member of the SoHo (sorbin-homology) family of adaptor proteins believed to play roles in cell adhesion, cytoskeletal organization, and signaling. We show here a novel splicing isoform of ArgBP2, i.e., ArgBP2™, composed of only three SH3 (src-homology 3) domains and structurally similar to vinexinß. We the...

journal_title：Medical molecular morphology

authors： Murase K,Ito H,Kanoh H,Sudo K,Iwamoto I,Morishita R,Soubeyran P,Seishima M,Nagata K

更新日期：2012-12-01 00:00:00

abstract：:Helicobacter pylori possesses intrabacterial nanotransportation system (ibNoTS) for transporting CagA, VacA, and urease within the bacterial cytoplasm, which is controlled by the extrabacterial environment. The route of ibNoTS for CagA is reported to be associated with the MreB filament, whereas the route of ibNoTS fo...

journal_title：Medical molecular morphology

authors： Wu H,Iwai N,Suzuki Y,Nakano T

更新日期：2019-12-01 00:00:00

abstract：:Dusp22 (dual-specificity phosphatase 22) is considered to regulate various cellular processes through the regulation of protein dephosphorylation. In this study, we prepared a specific antibody against Dusp22, anti-Dusp22, and carried out expression analyses with mouse tissues and cultured cell lines. Western blotting...

journal_title：Medical molecular morphology

authors： Hamada N,Mizuno M,Tomita H,Iwamoto I,Hara A,Nagata KI

更新日期：2018-06-01 00:00:00

abstract：:Generating mesenchymal stem-like cells (MSLCs) from induced pluripotent stem cells (iPSCs) can be a practical method for obtaining the sufficient cells for autologous tissue engineering. Single-cell culturing in specific medium and non-feeder cells is an alternative and promising strategy to overcome problems of embry...

journal_title：Medical molecular morphology

authors： Ueda M,Hashimoto Y,Honda Y,Baba S,Morita S

更新日期：2019-09-01 00:00:00

abstract：:Hirschsprung's disease is a congenital aganglionic neural disorder of the segmental distal intestine characterized by unsettled pathogenesis. The relationship between Hirschsprung's disease and pacemaker cells (PMC), which almost corresponds to that of the interstitial cells of Cajal (ICC), was morphologically observe...

journal_title：Medical molecular morphology

authors： Taniguchi K,Matsuura K,Matsuoka T,Nakatani H,Nakano T,Furuya Y,Sugimoto T,Kobayashi M,Araki K

更新日期：2005-06-01 00:00:00

abstract：:Lymphocyte enhancer factor 1 (LEF1), a member of the LEF/T-cell-specific factor (TCF) family of the high mobility group domain transcription factors, acts downstream in canonical Wnt signaling. Aberrant transactivation of LEF1 contributes to the tumorigenesis of colonic neoplasms, sebaceous skin tumors, and lymphoblas...

journal_title：Medical molecular morphology

authors： Shimomura A,Takasaki A,Nomura R,Hayashi N,Senda T

更新日期：2013-03-01 00:00:00

abstract：:Burow's solution has been shown to be effective against chronic suppurative otitis media and otitis externa. We demonstrated that Burow's solution had antibacterial effects against Staphylococcus aureus and Pseudomonas aeruginosa, inducing ultrastructural changes in these bacteria in vitro. S. aureus strain 209P and P...

journal_title：Medical molecular morphology

authors： Hyo Y,Yamada S,Ishimatsu M,Fukutsuji K,Harada T

更新日期：2012-06-01 00:00:00

abstract：:A 73-year-old woman showed marked exophytic growth of a tumor (25 × 23 × 14 mm) of the nipple over a period of 2 months. Histologically, numerous tumor nodules with no apparent keratinization were observed in the exophytic lesion. The tumor cells also showed little invasion to the dermis and no metastasis to the axill...

journal_title：Medical molecular morphology

authors： Hosaka N,Uesaka K,Takaki T,Zhang Y,Takasu K,Ikehara S

更新日期：2011-09-01 00:00:00

abstract：:In a case of metanephric adenoma of the kidney, many apical cytoplasmic blebs were found on the luminal surface of tumor cells. The tumor, measuring 15 mm in diameter, was found incidentally in the right kidney of a 40-year-old woman. It consisted of a dense proliferation of cuboidal cells forming small tubules of rou...

journal_title：Medical molecular morphology

authors： Shintaku M,Maeno K

更新日期：2016-03-01 00:00:00

abstract：:Brush cells (BCs) are relatively rare cells that are sparsely distributed throughout the mammalian digestive and respiratory systems. BCs have been identified in the rodent large intestine, but these cells have not been characterized by immunocytochemistry or electron microscopy. We previously demonstrated that rat bi...

journal_title：Medical molecular morphology

authors： Okamoto K,Hanazaki K,Akimori T,Okabayashi T,Okada T,Kobayashi M,Ogata T

更新日期：2008-09-01 00:00:00

abstract：:A 59-year-old Japanese man presented with a giant submucosal tumor with ulceration during follow-up of duodenal ulcer. Pancreaticoduodenectomy was undertaken, and subsequent histological examination of the tumor disclosed anaplastic carcinoma of the pancreas head. The carcinoma components contained adenocarcinoma and ...

journal_title：Medical molecular morphology

authors： Kuroda N,Iwamura S,Fujishima N,Ohara M,Hirouchi T,Mizuno K,Hayashi Y,Lee GH

更新日期：2007-09-01 00:00:00

abstract：:Our study was designed to clarify the role of antioxidant enzymes in the rat von Ebner gland during acute nickel toxicity. After treatment with nickel acetate, we monitored ultrastructural alterations in acinar and ductal cells, immunohistochemical staining for glutathione peroxidase (GPx) and glutathione S-transferas...

journal_title：Medical molecular morphology

authors： Shiraishi M,Doi Y,Kayashima K,Fujimoto S

更新日期：2008-03-01 00:00:00

abstract：:Extra-gastrointestinal stromal tumors (E-GISTs) not associated with the alimentary tract in the pelvic cavity are extremely rare. We treated a 49-year-old Japanese man with such an E-GIST in the pelvic cavity who underwent an intrapelvic tumorectomy with a total prostatectomy and partial rectum resection. Gross examin...

journal_title：Medical molecular morphology

authors： Hirano H,Yoshida T,Yoshimura H,Fukuoka M,Ohmura N,Nishizawa Y,Tachibana S,Hirota S,Zozumi M,Nishigami T

更新日期：2012-06-01 00:00:00

abstract：:Cancer cells surviving in ascites exhibit cancer stem cell (CSC)-like features. This study analyzed the expression of the CSC marker CD133 in the ascites-derived exosomes obtained from patients with unresectable pancreatic cancer. In addition, inverse correlation of CD133 expression with prognosis was examined. Of the...

journal_title：Medical molecular morphology

authors： Sakaue T,Koga H,Iwamoto H,Nakamura T,Ikezono Y,Abe M,Wada F,Masuda A,Tanaka T,Fukahori M,Ushijima T,Mihara Y,Naitou Y,Okabe Y,Kakuma T,Ohta K,Nakamura KI,Torimura T

更新日期：2019-12-01 00:00:00

abstract：:Aquaporins (AQPs) are key regulators of water channels across the cell cytoplasm. Little is known about AQP localization and changes in the hepatic microvascular system. This study aimed to clarify the localization of AQP-1 in the microvessels in normal and cirrhotic rat liver. To establish a rat cirrhosis model, thio...

journal_title：Medical molecular morphology

authors： Yokomori H,Oda M,Yoshimura K,Watanabe S,Hibi T

更新日期：2010-03-01 00:00:00

abstract：:In the human placenta, embryo-derived trophoblasts aggressively invade maternal spiral arteries and transform the arteries to low-resistance large-caliber vessels. This process, which ensures adequate placental perfusion, is called maternal vascular remodeling. Histological examination showed deposition of maternal pl...

journal_title：Medical molecular morphology

authors： Sato Y,Fujiwara H,Konishi I

更新日期：2010-09-01 00:00:00

abstract：:The normal mammary gland can be roughly divided into the large duct close to the nipple and the terminal duct located within the lobulus. Both the large duct and the terminal duct are composed of epithelial cells and myoepithelial cells. The epithelial cells can be divided into light and dark cells using electron dens...

journal_title：Medical molecular morphology

authors： Tsuchiya S,Li F

更新日期：2005-12-01 00:00:00

abstract：:The present study was conducted to address the molecular pathogenesis underlying the progression of basal cell carcinoma (BCC) in a nevoid basal cell carcinoma syndrome (NBCCS) patient. We analyzed infiltrative BCCs that invaded the subcutaneous tissue of the scalp and penetrated the skull in a 61-year-old Japanese fe...

journal_title：Medical molecular morphology

authors： Tate G,Kishimoto K,Mitsuya T

更新日期：2015-09-01 00:00:00

abstract：:Carcinoma follows a course of multiple changes that are affected by several important factors, with epigenetic silencing of the promoter gene being one of them. A series of studies have suggested that epigenetic changes in the anti-aging gene Klotho may be one of the emerging areas of concern in the study of carcinoge...

journal_title：Medical molecular morphology

authors： Adhikari BR,Uehara O,Matsuoka H,Takai R,Harada F,Utsunomiya M,Chujo T,Morikawa T,Shakya M,Yoshida K,Sato J,Arakawa T,Nishimura M,Nagayasu H,Chiba I,Abiko Y

更新日期：2017-09-01 00:00:00

abstract：:In the process of ovary sexual maturation, most immature ovarian follicles degrade into atretic follicles accompanied by apoptosis in granulosa cells. Macrophages can recognize apoptotic cells through specific binding with phosphatidylserine (PS), exposed on the surface of apoptotic cells, which is mediated by milk-fa...

journal_title：Medical molecular morphology

authors： Naka M,Kusakabe K,Takeshita A,Nakagawa H,Ito Y,Shibata MA,Otsuki Y

更新日期：2009-09-01 00:00:00

abstract：:Uterine leiomyoma is the most common tumor in the female genital tract, although its pathogenesis remains unclear. Molecular analyses have demonstrated that each leiomyoma nodule is monoclonal and harbors various DNA abnormalities, suggesting that DNA damage in normal smooth muscle cells plays an important role in the...

journal_title：Medical molecular morphology

authors： Suzuki A,Kariya M,Matsumura N,Baba T,Yagi H,Mandai M,Konishi I,Fujii S

更新日期：2012-12-01 00:00:00

abstract：:The establishment of consistent and reliable methods for the analysis of atherosclerosis molecular pathways and for testing the efficiency of new therapeutics is of utmost importance. Here, we fed ApoE-knockout (KO) mice with high-fat diet to for 16 weeks to induce atherosclerosis. Atherosclerotic lesions in mice were...

journal_title：Medical molecular morphology

authors： Shibata MA,Shibata E,Maemura K,Kondo Y,Harada-Shiba M

更新日期：2017-09-01 00:00:00

abstract：:It is well accepted that cell cycle regulators are strongly implicated in the progression of cancer development. p16 and p27 are potent cyclin-dependent kinase (CDK) inhibitors involved in G1 phase progression, and are regarded as adverse prognostic biomarkers for various types of cancers. It has been reported that th...

journal_title：Medical molecular morphology

authors： Matsuda Y,Wakai T,Kubota M,Takamura M,Yamagiwa S,Aoyagi Y,Osawa M,Fujimaki S,Sanpei A,Genda T,Ichida T

更新日期：2013-12-01 00:00:00

abstract：:We studied the distribution of myofibroblasts in the stroma of normal seminal vesicles. Twelve normal seminal vesicles obtained by surgery on the diagnosis of some diseases were selected, and we evaluated the distribution of myofibroblasts in the seminal vesicles using immunohistochemical and electron and immunoelectr...

journal_title：Medical molecular morphology

authors： Shimasaki N,Kuroda N,Miyazaki E,Hayashi Y,Toi M,Hiroi M,Enzan H,Shuin T

更新日期：2007-12-01 00:00:00

abstract：:In the present study, we investigated the changes in the localization of the glucose transporter GLUT2 and the fructose transporter GLUT5 in small intestinal absorptive cells during postnatal development, especially during the weaning period, using immunohistochemistry and confocal laser scanning microscopy. In the je...

journal_title：Medical molecular morphology

authors： Baba R,Yamami M,Sakuma Y,Fujita M,Fujimoto S

更新日期：2005-03-01 00:00:00

abstract：:We examined the effects of low protein intake on the development of the remaining kidney in subtotally (5/6) nephrectomized immature rats. Three-week-old rats were kept on a diet containing either 12% protein (Lp rats) or 18% protein (Np rats) for 4 or 8 weeks after subtotal nephrectomy (SUNx). In Western blot analysi...

journal_title：Medical molecular morphology

authors： Mino M,Ihara H,Kozaki S,Kondo T,Takeshita A,Kusakabe KT,Okada T

更新日期：2010-06-01 00:00:00

abstract：:Non-invasive predictors for the development of cirrhosis-related conditions are needed for patients with primary biliary cholangitis (PBC). We investigated the association between cytokeratin-18 fragments (M30 and M65) and liver histology, treatment response and the development of cirrhosis-related conditions in patie...

journal_title：Medical molecular morphology

authors： Hayashi M,Abe K,Fujita M,Okai K,Takahashi A,Nozawa Y,Ohira H

更新日期：2018-09-01 00:00:00

abstract：:Wilson disease (WD) is a major type of primary copper toxicosis associated with hypoceruloplasminemia, while idiopathic copper toxicosis (ICT) is a minor type characterized by normoceruloplasminemia. Because ceruloplasmin is the major circulating ferroxidase, iron metabolism may be affected in patients with WD. Biopsi...

journal_title：Medical molecular morphology

authors： Hayashi H,Hattori A,Tatsumi Y,Hayashi K,Katano Y,Ueyama J,Wakusawa S,Yano M,Goto H

更新日期：2013-09-01 00:00:00